Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Stephen B Melville"'
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133217 (2015)
Among many other virulence factors, Clostridium perfringens produces three sialidases NanH, NanI and NanJ. NanH lacks a secretion signal peptide and is predicted to be an intracellular enzyme, while NanI and NanJ are secreted. Previously, we had iden
Externí odkaz:
https://doaj.org/article/63f7cad996ff4a179a521ee9a89e00c4
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95781 (2014)
Bacterial endospores exhibit extreme resistance to most conditions that rapidly kill other life forms, remaining viable in this dormant state for centuries or longer. While the majority of Bacillus subtilis dormant spores germinate rapidly in respons
Externí odkaz:
https://doaj.org/article/3e5a87de8e8040ae83fada24b46c4e76
Autor:
Samantha R. Soncini, Andrea H. Hartman, Tara M. Gallagher, Gary J. Camper, Roderick V. Jensen, Stephen B. Melville
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-24 (2020)
Abstract Background Clostridium perfringens is a Gram-positive anaerobic pathogen that causes multiple diseases in humans and animals. C. perfringens lack flagella but have type IV pili (TFP) and can glide on agar surfaces. When C. perfringens bacter
Externí odkaz:
https://doaj.org/article/bfbb7df663fb41fb8da570898656b105
Autor:
Ann M. Stevens, Ann C. Smith, Gili Marbach-Ad, Sarah A. Balcom, John Buchner, Sandra L. Daniel, Jeffrey J. DeStefano, Najib M. El-Sayed, Kenneth Frauwirth, Vincent T. Lee, Kevin S. McIver, Stephen B. Melville, David M. Mosser, David L. Popham, Birgit E. Scharf, Florian D. Schubot, Richard W. Seyler, Patricia Ann Shields, Wenxia Song, Daniel C. Stein, Richard C. Stewart, Katerina V. Thompson, Zhaomin Yang, Stephanie A. Yarwood
Publikováno v:
Journal of Microbiology & Biology Education, Vol 18, Iss 1 (2017)
Misconceptions, also known as alternate conceptions, about key concepts often hinder the ability of students to learn new knowledge. Concept inventories (CIs) are designed to assess students’ understanding of key concepts, especially those prone to
Externí odkaz:
https://doaj.org/article/6a3203f4342c4b76af586e7503688783
Publikováno v:
Biophys J
Contrasting most known bacterial motility mechanisms, a bacterial sliding motility discovered in at least two gram-positive bacterial families does not depend on designated motors. Instead, the cells maintain end-to-end connections following cell div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8027ba832c9d54bb75470e1f7d7b6194
https://europepmc.org/articles/PMC9279174/
https://europepmc.org/articles/PMC9279174/
Autor:
Hualan Liu, Stephen B. Melville, Ramnik J. Xavier, Chelsi D. Cassilly, Damian R. Plichta, Hera Vlamakis, David R Jackson, Jon Clardy
Publikováno v:
ACS Chemical Biology. 16:6-13
Plasmalogens are vinyl ether-containing lipids produced by mammals and bacteria. The aerobic biosynthetic pathway in eukaryotes and bacteria is known, but the anaerobic pathway has remained a mystery. Here, we describe a two-gene operon (plasmalogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c6fb9a88d06f7c14fd449d910d21d9
https://doi.org/10.1021/acschembio.0c00673
https://doi.org/10.1021/acschembio.0c00673
Autor:
Tara Gallagher, Gary J. Camper, Roderick V. Jensen, Stephen B. Melville, Samantha R. Soncini, Andrea H. Hartman
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-24 (2020)
BMC Genomics
BMC Genomics
Background Clostridium perfringens is a Gram-positive anaerobic pathogen that causes multiple diseases in humans and animals. C. perfringens lack flagella but have type IV pili (TFP) and can glide on agar surfaces. When C. perfringens bacteria are pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fde537b1a9e09c7109d58d83711e05
https://doaj.org/article/bfbb7df663fb41fb8da570898656b105
https://doaj.org/article/bfbb7df663fb41fb8da570898656b105
Publikováno v:
Journal of Microbiological Methods. 199:106519
Clostridium perfringens is a Gram-positive pathogen with low GC content. To identify genes that are transcribed at higher levels when the bacteria grow on a surface, we used RNA-seq in a previous study to measure global transcript levels of cells gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8f91aaafe5b4c7cf223c436e103f6f
https://doi.org/10.1016/j.mimet.2022.106519
https://doi.org/10.1016/j.mimet.2022.106519
Autor:
Angela Saadat, Stephen B. Melville
Publikováno v:
J Bacteriol
Large clostridial toxins (LCTs) are secreted virulence factors found in several species, including Clostridioides difficile, Clostridium perfringens, Paeniclostridium sordellii, and Clostridium novyi. LCTs are large toxins that lack a secretion signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d434235542278b1bf4b0c6436df92af
https://doi.org/10.1128/jb.00580-20
https://doi.org/10.1128/jb.00580-20
Autor:
David R, Jackson, Chelsi D, Cassilly, Damian R, Plichta, Hera, Vlamakis, Hualan, Liu, Stephen B, Melville, Ramnik J, Xavier, Jon, Clardy
Publikováno v:
ACS Chem Biol
[Image: see text] Plasmalogens are vinyl ether-containing lipids produced by mammals and bacteria. The aerobic biosynthetic pathway in eukaryotes and bacteria is known, but the anaerobic pathway has remained a mystery. Here, we describe a two-gene op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::952ca7d634e740ddb09310f0a9192065
https://pubmed.ncbi.nlm.nih.gov/33350306
https://pubmed.ncbi.nlm.nih.gov/33350306