Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Stephen B Bocckino"'
Autor:
Stephen B Bocckino, Brian J. Day, Michael P. Trova, Livia Gregor-Boros, Polivina Jolicia F Gauuan, James D. Crapo
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:3013-3021
Carboxylic ester and amide-substituted analogues of [5,10,15,20-tetrakis(4-carboxyphenyl)-porphyrinato]manganese(III) chloride (MnTBAP) were synthesized and assayed as potential superoxide dismutase (SOD) mimetics. The tetraester analogues 4a and 4b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3055c38a4fe72833315ab59c97bd5b4e
https://doi.org/10.1016/s0968-0896(02)00153-0
https://doi.org/10.1016/s0968-0896(02)00153-0
Publikováno v:
Carcinogenesis. 13:1113-1120
The levels of protein kinase C (PKC) activity, PKC isozymes, as well as the level of endogenous diacylglycerols (DAG) were examined in early emergence mouse skin papillomas and compared to the levels in the epidermis. The papillomas were derived from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cfc72a15a2ea73a9da5763b3efde09
https://doi.org/10.1093/carcin/13.7.1113
https://doi.org/10.1093/carcin/13.7.1113
Autor:
G R Cunningham, Stanford J. Stewart, Stephen B. Bocckino, Linda L. Kelley, Frances S. House, J A Strupp, John H. Exton, G S Henderson
Publikováno v:
Cell Regulation. 2:841-850
A number of cellular signaling systems are called into play by interaction of the T lymphocyte antigen receptor/CD3 complex with its cognate antigen. Well-described signaling systems include phosphoinositide turnover, tyrosine phosphorylation, protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c376ef7e2c2512efcbef636bb9c6333
https://doi.org/10.1091/mbc.2.10.841
https://doi.org/10.1091/mbc.2.10.841
Publikováno v:
Proceedings of the National Academy of Sciences. 88:6210-6213
Phosphatidate-dependent protein phosphorylation was observed in soluble extracts from rat liver, brain, lung, and testis. The phosphorylation was stimulated by free Ca2+ in the range of 360-800 nM. Incubation mixtures containing phosphatidate provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dae9b59bcef8a7849be5037c4271f84
https://doi.org/10.1073/pnas.88.14.6210
https://doi.org/10.1073/pnas.88.14.6210
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1055:69-74
A vasopressin receptor was purified, using a novel affinity column, from rat liver plasma membranes treated with guanosine 5′-(3-O-thio)triphosphate and solubilized with 0.8% cholate. Incubation of the membranes with the GTP analogue resulted in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7faf542d958e1fbe812117ba962ba66
https://doi.org/10.1016/0167-4889(90)90092-r
https://doi.org/10.1016/0167-4889(90)90092-r
Publikováno v:
Ciba Foundation Symposium 164-Interactions Among Cell Signalling Systems
Two G proteins that regulate phosphoinositide phospholipase C in liver plasma membranes have been purified to homogeneity in both the heterotrimeric and dissociated forms. The heterotrimers contain a 42 kDa or 43 kDa alpha subunit and a 35 kDa beta s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5418acf699357c7aa0d3abc47262a05a
https://doi.org/10.1002/9780470514207.ch4
https://doi.org/10.1002/9780470514207.ch4
Autor:
Brian J. Day, Polivina Jolicia F Gauuan, Stephen M Bubb, Michael P. Trova, Stephen B Bocckino, Anthony D. Pechulis, James D. Crapo
Publikováno v:
Bioorganicmedicinal chemistry. 11(13)
Novel glyoxylate- and glyoxamide-derived metalloporphyrins 26-58 were synthesized and evaluated as potential superoxide dismutase (SOD) mimetics. Relative to previously studied MnTBAP analogues, the glyoxylate-derived metalloporphyrins 32, 39, and 54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd65726cd83d879ec7254a261b7be850
https://pubmed.ncbi.nlm.nih.gov/12788343
https://pubmed.ncbi.nlm.nih.gov/12788343
Autor:
Stephen B. Bocckino, John H. Exton
Publikováno v:
Lipid Second Messengers ISBN: 9781489913630
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63c7c522d70b577d0d06b75e4bd98dd3
https://doi.org/10.1007/978-1-4899-1361-6_3
https://doi.org/10.1007/978-1-4899-1361-6_3
Autor:
John H. Exton, Stephen B. Bocckino
Publisher Summary This chapter provides an overview of phosphatidylcholine metabolism in signal transduction. Although the hepatocyte is not an inflammatory cell, there is reason to believe that many of the signaling pathways found in the hepatocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a193514be4502a89f7e90417dd4f432
https://doi.org/10.1016/b978-0-12-150403-8.50007-5
https://doi.org/10.1016/b978-0-12-150403-8.50007-5
Publikováno v:
Molecular and Cellular Biochemistry. 104
There is much evidence that G-proteins transduce the signal from receptors for Ca(2+)-mobilizing agonists to the phospholipase C that catalyzes the hydrolysis of phosphoinositides. However, the specific G-proteins involved have not been identified. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6eb570a8dadf7b68993d5d2638a96c1
https://doi.org/10.1007/bf00229807
https://doi.org/10.1007/bf00229807