Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Stephen B, Heitner"'
Autor:
Supriya Shore, Michael Butzner, Claire Ervin, Katherine Kosa, Sheri Fehnel, Lisa Salberg, Stephen B Heitner, Daniel Jacoby, Sara Saberi
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Objective Hypertrophic cardiomyopathy (HCM), including obstructive HCM (oHCM), is the most common inherited cardiomyopathy causing lifestyle-limiting symptoms. Data are lacking about patients’ perspectives on the daily impact of their symptoms. Thi
Externí odkaz:
https://doaj.org/article/128c07b1af784bd68c5953c9e6312a65
Autor:
Caroline J. Coats, Ahmad Masri, Michael E. Nassif, Roberto Barriales‐Villa, Michael Arad, Nuno Cardim, Lubna Choudhury, Brian Claggett, Hans‐Dirk Düngen, Pablo Garcia‐Pavia, Albert A. Hagège, James L. Januzzi, Matthew M. Y. Lee, Gregory D. Lewis, Chang‐Sheng Ma, Martin S. Maron, Zi Michael Miao, Michelle Michels, Iacopo Olivotto, Artur Oreziak, Anjali T. Owens, John A. Spertus, Scott D. Solomon, Jacob Tfelt‐Hansen, Marion van Sinttruije, Josef Veselka, Hugh Watkins, Daniel L. Jacoby, Polina German, Stephen B. Heitner, Stuart Kupfer, Justin D. Lutz, Fady I. Malik, Lisa Meng, Amy Wohltman, Theodore P. Abraham
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Aficamten, a novel cardiac myosin inhibitor, reversibly reduces cardiac hypercontractility in obstructive hypertrophic cardiomyopathy. We present a prespecified analysis of the pharmacokinetics, pharmacodynamics, and safety of aficamten in
Externí odkaz:
https://doaj.org/article/ecd7f5b3949f4a8ca276c42cd7292a3f
Autor:
Dan Liang, Aleksei Mikhalchenko, Hong Ma, Nuria Marti Gutierrez, Tailai Chen, Yeonmi Lee, Sang-Wook Park, Rebecca Tippner-Hedges, Amy Koski, Hayley Darby, Ying Li, Crystal Van Dyken, Han Zhao, Keliang Wu, Jingye Zhang, Zhenzhen Hou, Seongjun So, Jongsuk Han, Jumi Park, Chong-Jai Kim, Kai Zong, Jianhui Gong, Yilin Yuan, Ying Gu, Yue Shen, Susan B. Olson, Hui Yang, David Battaglia, Thomas O’Leary, Sacha A. Krieg, David M. Lee, Diana H. Wu, P. Barton Duell, Sanjiv Kaul, Jin-Soo Kim, Stephen B. Heitner, Eunju Kang, Zi-Jiang Chen, Paula Amato, Shoukhrat Mitalipov
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
DNA repair in response to DSBs in the preimplantation embryo is hard to analyze. Here the authors show that over 25% of pre-existing heterozygous loci in control single blastomere samples appeared as homozygous after whole genome amplification, there
Externí odkaz:
https://doaj.org/article/ba06b7898e994b68a92e8beb9b442fb5
Autor:
Paola Roldan, Sriram Ravi, James Hodovan, J. Todd Belcik, Stephen B. Heitner, Ahmad Masri, Jonathan R. Lindner
Publikováno v:
Cardiovascular Ultrasound, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Perfusion defects during stress can occur in hypertrophic cardiomyopathy (HCM) from either structural or functional abnormalities of the coronary microcirculation. In this study, vasodilator stress myocardial contrast echocardiogr
Externí odkaz:
https://doaj.org/article/265c4ae388d24679884be3b5cc6eef65
Autor:
Josephine Harrington, Jie‐Lena Sun, Gregg C. Fonarow, Stephen B. Heitner, Punag H. Divanji, Gary Binder, Larry A. Allen, Brooke Alhanti, Clyde W. Yancy, Nancy M. Albert, Adam D. DeVore, G. Michael Felker, Stephen J. Greene
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 10 (2023)
Background Many patients with heart failure (HF) have severely reduced ejection fraction but do not meet threshold for consideration of advanced therapies (ie, stage D HF). The clinical profile and health care costs associated with these patients in
Externí odkaz:
https://doaj.org/article/1562516935a04e21a697a6a639dfaab1
Autor:
Evan F. Shalen, Stephen B. Heitner, Lana Al‐Rashdan, Reyhaneh Akhavein, Miriam R. Elman, Katherine L. Fischer, Lucy Q. Lin, Meghan Mannello, Babak Nazer, Howard K. Song, Ahmad Masri
Publikováno v:
ESC Heart Failure, Vol 8, Iss 6, Pp 4791-4799 (2021)
Abstract Aims Amiodarone reduces the incidence of atrial fibrillation (AF) following coronary artery bypass surgery; however, the benefit of perioperative amiodarone in patients undergoing septal myectomy (SM) for obstructive hypertrophic cardiomyopa
Externí odkaz:
https://doaj.org/article/138fe5a52fc94df8bbc4ea8540a0f52b
Autor:
David E. Lanfear, Joyce N. Njoroge, Kirkwood F. Adams, Inder Anand, James C. Fang, Felix Ramires, Karen Sliwa-Hahnle, Aysha Badat, Lesley Burgess, Eiran Z. Gorodeski, Celeste Williams, Rafael Diaz, Gary M. Felker, John J.V. McMurray, Marco Metra, Scott Solomon, Zi Michael Miao, Brian L. Claggett, Stephen B. Heitner, Stuart Kupfer, Fady I. Malik, John R. Teerlink
Publikováno v:
JACC: Heart Failure. 11:569-579
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efc753d950073683c1fc7389273a42c3
https://doi.org/10.1016/j.jchf.2022.11.021
https://doi.org/10.1016/j.jchf.2022.11.021
Autor:
Rajshekhar Chakraborty, Rachael Sexton, Suzanne Lentzsch, Muneer H. Abidi, Peter M. Voorhees, Adam D Cohen, Eric Rohren, Stephen B. Heitner, Kevin R. Kelly, Niklas J Mackler, David M. Baer, Antje Hoering, Brian G.M. Durie, Sikander Ailawadhi, Robert Z. Orlowski
Publikováno v:
Blood. 140:4349-4351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f465707f503f9dfb5e81ea3003f916c
https://doi.org/10.1182/blood-2022-166609
https://doi.org/10.1182/blood-2022-166609
Autor:
Marco Metra, Matteo Pagnesi, Brian L Claggett, Rafael Díaz, G Michael Felker, John J V McMurray, Scott D Solomon, Diana Bonderman, James C Fang, Cândida Fonseca, Eva Goncalvesova, Jonathan G Howlett, Jing Li, Eileen O’Meara, Zi Michael Miao, Siddique A Abbasi, Stephen B Heitner, Stuart Kupfer, Fady I Malik, John R Teerlink
Publikováno v:
European Heart Journal. 43:5006-5016
Aim Patients with heart failure with reduced ejection fraction and low systolic blood pressure (SBP) have high mortality, hospitalizations, and poorly tolerate evidence-based medical treatment. Omecamtiv mecarbil may be particularly helpful in such p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4948dc65d3217fd0e4fab58ab3eb5d2c
https://doi.org/10.1093/eurheartj/ehac293
https://doi.org/10.1093/eurheartj/ehac293
Autor:
Ethan J, Rowin, Martin S, Maron, Arnon, Adler, Alfred J, Albano, Armanda M, Varnava, Danna, Spears, Dana, Marsy, Stephen B, Heitner, Emilie, Cohen, Kevin M W, Leong, Stephen L, Winters, Matthew W, Martinez, Benjamin C, Koethe, Harry, Rakowski, Barry J, Maron
Publikováno v:
Heart Rhythm. 19:782-789
The sudden death (SD) risk stratification algorithm in hypertrophic cardiomyopathy (HCM) has evolved, underscored recently by novel cardiac magnetic resonance (CMR)-based risk markers (left ventricular apical aneurysm, extensive late gadolinium enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780a6b3affe6352054d9e9ab0320ec8c
https://doi.org/10.1016/j.hrthm.2021.12.017
https://doi.org/10.1016/j.hrthm.2021.12.017