Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Stephen Albert Johnston"'
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Purpose To evaluate a new class of blood-based biomarkers, anti-frameshift peptide antibodies, for predicting both tumor responses and adverse immune events to immune checkpoint inhibitor (ICI) therapies in advanced lung cancer patients. Exp
Externí odkaz:
https://doaj.org/article/93e22905aa9e4ceaa5ae5045789ad2b5
Autor:
Milene Peterson, Sierra Nicole Murphy, John Lainson, Jian Zhang, Luhui Shen, Chris W. Diehnelt, Stephen Albert Johnston
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background It is widely hoped that personal cancer vaccines will extend the number of patients benefiting from checkpoint and other immunotherapies. However, it is clear creating such vaccines will be challenging. It requires obtaining and s
Externí odkaz:
https://doaj.org/article/f77f6689e82640a88f053e42321002b6
Autor:
Phillip Stafford, Stephen Albert Johnston, Orhun H Kantarci, Ameneh Zare-Shahabadi, Arthur Warrington, Moses Rodriguez
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229080 (2020)
Therapeutic monoclonal antibodies have the potential to work as biological therapeutics. OKT3, Herceptin, Keytruda and others have positively impacted healthcare. Antibodies evolved naturally to provide high specificity and high affinity once mature.
Externí odkaz:
https://doaj.org/article/bfbc224862bf4fd68945028b4bd55d8c
Autor:
Denicar Lina Nascimento Fabris Maeda, Milene Tavares Batista, Lennon Ramos Pereira, Mariana de Jesus Cintra, Jaime Henrique Amorim, Camila Mathias-Santos, Sara Araújo Pereira, Silvia Beatriz Boscardin, Sandriana dos Ramos Silva, Eliana L. Faquim-Mauro, Vanessa Barbosa Silveira, Danielle Bruna Leal Oliveira, Stephen Albert Johnston, Luís Carlos de Souza Ferreira, Juliana Falcão Rodrigues
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The heat-labile toxins (LT) produced by enterotoxigenic Escherichia coli display adjuvant effects to coadministered antigens, leading to enhanced production of serum antibodies. Despite extensive knowledge of the adjuvant properties of LT derivatives
Externí odkaz:
https://doaj.org/article/7c7786f8ad52411e9d16990e3f04ab1c
Autor:
Janine Mansi, Franklin I. Aigbirhio, Vijay Vaja, Robert Punjani, Rathi Ramakrishnan, Stephen Albert Johnston, Laura M. Kenny, S. Hope McDevitt, Gary Cook, Eric O. Aboagye, Gosala S. Gopalakrishnan, Duncan Hiscock, Fiona J. Gilbert, Naina Patel, Tara Barwick, Neva Patel
Publikováno v:
Cancer Research. 81:PD6-09
Background 20% of breast cancers have over-expression of the human epidermal growth factor receptor-2 (HER2), which is an adverse prognostic factor and used to guide therapy selection. At present HER2 expression can only be determined using biopsy ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cfca53432a11cd11c896ab5a830053a
https://doi.org/10.1158/1538-7445.sabcs20-pd6-09
https://doi.org/10.1158/1538-7445.sabcs20-pd6-09
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157462 (2016)
Antigen-antibody complexes are central players in an effective immune response. However, finding those interactions relevant to a particular disease state can be arduous. Nonetheless many paths to discovery have been explored since deciphering these
Externí odkaz:
https://doaj.org/article/2117021cecb34ed7bbca7a312d120e6a
Autor:
Jaishri O. Blakeley, Cynthia Hawkins, Fausto J. Rodriguez, Stefan M. Pfister, Uri Tabori, Brian R. Rood, Antonio Iavarone, Roger J. Packer, Eric Bouffet, Tobey J. MacDonald, Stephen Albert Johnston, David T.W. Jones, Lindsay Kilburn, David H. Gutmann, Michael Fisher, Eugene Hwang, Yuan Zhu, Vijay Ramaswamy, Jason Fangusaro
Publikováno v:
Neuro-Oncology
Gliomas are the most common primary central nervous system tumors occurring in children and adults with neurofibromatosis type 1 (NF1). Over the past decade, discoveries of the molecular basis of low-grade gliomas (LGGs) have led to new approaches fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1334821d9e709090420ee5bb72681b0d
http://europepmc.org/articles/PMC7283027
http://europepmc.org/articles/PMC7283027
Autor:
Stephen Albert Johnston, John C. Lainson, Zhan Gong Zhao, Kathryn Sykes, Chris W. Diehnelt, Luhui Shen, Justin R. Brown
Publikováno v:
RSC Advances. 10:29675-29681
Parallel measurement of large numbers of antigen–antibody interactions are increasingly enabled by peptide microarray technologies. Our group has developed an in situ synthesized peptide microarray of >400 000 frameshift neoantigens using mask-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bf86667492fb4c241f7a488a8aa612
https://doi.org/10.1039/d0ra05267a
https://doi.org/10.1039/d0ra05267a
Autor:
V. Drozd, J. Shoikhet, Kristina E. Abramova, A. Gordeeva, E. A. Kolosova, Andrei I. Chapoval, Stephen Albert Johnston, A. F. Lazarev
Publikováno v:
BIOTECHNOLOGY: STATE OF THE ART AND PERSPECTIVES. :167-169
In this work, the results of work on the assessment of the repertoire of circulating antibodies using a technological platform - peptide microarray. In the course of the work, peptides were identified that interact with circulating antibodies in bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e609934fe3e7f3e4edb5a3d04f2f68
https://doi.org/10.37747/2312-640x-2020-18-167-169
https://doi.org/10.37747/2312-640x-2020-18-167-169
Publikováno v:
BioTechniques, Vol 34, Iss 2, Pp 244-250 (2003)
Externí odkaz:
https://doaj.org/article/33219ea969b042508241c49da3f76a4e