Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Stephen A. Richardson"'
Autor:
Zhijia Tan, Peikai Chen, Xiaonan Dong, Shuang Guo, Victor Y.L. Leung, Jason P.Y. Cheung, Danny Chan, Stephen M. Richardson, Judith A. Hoyland, Michael K.T. To, Kathryn S.E. Cheah
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114342- (2024)
Summary: The nucleus pulposus (NP) in the intervertebral disc (IVD) arises from embryonic notochord. Loss of notochordal-like cells in humans correlates with onset of IVD degeneration, suggesting that they are critical for healthy NP homeostasis and
Externí odkaz:
https://doaj.org/article/4189f7cad7104b8e98f2847ca14bb149
Autor:
Hamish T. J. Gilbert, Francis E. J. Wignall, Leo Zeef, Judith A. Hoyland, Stephen M. Richardson
Publikováno v:
JOR Spine, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background Stem cell‐based therapies show promise as a means of repairing the degenerate intervertebral disc, with growth factors often used alongside cells to help direct differentiation toward a nucleus pulposus (NP)‐like phenotype. We
Externí odkaz:
https://doaj.org/article/f8b692db93254d40900f6b8607d1f59b
Autor:
Rebecca J. Williams, Lisanne T. Laagland, Frances C. Bach, Lizzy Ward, Wilson Chan, Vivian Tam, Adel Medzikovic, Shaghayegh Basatvat, Lily Paillat, Nicolas Vedrenne, Joseph W. Snuggs, Deepani W. Poramba‐Liyanage, Judith A. Hoyland, Danny Chan, Anne Camus, Stephen M. Richardson, Marianna A. Tryfonidou, Christine L. Le Maitre
Publikováno v:
JOR Spine, Vol 6, Iss 3, Pp n/a-n/a (2023)
Abstract Background Lineage‐tracing experiments have established that the central region of the mature intervertebral disc, the nucleus pulposus (NP), develops from the embryonic structure called “the notochord”. However, changes in the cells d
Externí odkaz:
https://doaj.org/article/dfa01fb81efe46eab3be07a579ca5024
Autor:
Shaghayegh Basatvat, Frances C. Bach, Marcos N. Barcellona, Abbie L. Binch, Conor T. Buckley, Brian Bueno, Nadeen O. Chahine, Ana Chee, Laura B. Creemers, Stefan Dudli, Bailey Fearing, Stephen J. Ferguson, Jennifer Gansau, Benjamin Gantenbein, Rahul Gawri, Juliane D. Glaeser, Sibylle Grad, Julien Guerrero, Lisbet Haglund, Paula A. Hernandez, Judith A. Hoyland, Charles Huang, James C. Iatridis, Svenja Illien‐Junger, Liufang Jing, Petra Kraus, Lisanne T. Laagland, Gernot Lang, Victor Leung, Zhen Li, Thomas Lufkin, Josette C. vanMaanen, Emily E. McDonnell, Chris J. Panebianco, Steven M. Presciutti, Sanjna Rao, Stephen M. Richardson, Sarah Romereim, Tara C. Schmitz, Jordy Schol, Lori Setton, Dmitriy Sheyn, Joseph W. Snuggs, Y. Sun, Xiaohong Tan, Marianna A. Tryfonidou, Nam Vo, Dong Wang, Brandon Williams, Rebecca Williams, S. Tim Yoon, Christine L. Le Maitre
Publikováno v:
JOR Spine, Vol 6, Iss 1, Pp n/a-n/a (2023)
Abstract Background In vitro studies using nucleus pulposus (NP) cells are commonly used to investigate disc cell biology and pathogenesis, or to aid in the development of new therapies. However, lab‐to‐lab variability jeopardizes the much‐need
Externí odkaz:
https://doaj.org/article/4cf7143b0ac5450a9e437e4c96e1d1cf
Autor:
Maria C. Arno, Maria Inam, Andrew C. Weems, Zehua Li, Abbie L. A. Binch, Christopher I. Platt, Stephen M. Richardson, Judith A. Hoyland, Andrew P. Dove, Rachel K. O’Reilly
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The ability to control nanostructure shape and dimensions presents opportunities to design materials in which their macroscopic properties are dependent upon the nature of the nanoparticle. Here the authors show nanoparticle shape is a critical consi
Externí odkaz:
https://doaj.org/article/44fdf95efe6e410eab9134e1f95f3977
Publikováno v:
Marine Drugs, Vol 21, Iss 2, p 59 (2023)
Collagen is the most ubiquitous biomacromolecule found in the animal kingdom and is commonly used as a biomaterial in regenerative medicine therapies and biomedical research. The collagens used in these applications are typically derived from mammali
Externí odkaz:
https://doaj.org/article/e57d7cd7f0814dcfa17c0f0d50380819
Autor:
Hamish T. J. Gilbert, Venkatesh Mallikarjun, Oana Dobre, Mark R. Jackson, Robert Pedley, Andrew P. Gilmore, Stephen M. Richardson, Joe Swift
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Cells must be robust to the mechanical demands of their environments. Here, Gilbert et al. expose cells to high-intensity strain cycling and use proteomics to identify a protein, SUN2, that behaves as a strain-induced breakpoint that can decouple the
Externí odkaz:
https://doaj.org/article/f8f759b44d8640cea035f511934e57db
Publikováno v:
Groundwater Monitoring & Remediation. 43:90-97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::118dfb10a531ff74c0e95c7276719009
https://doi.org/10.1111/gwmr.12572
https://doi.org/10.1111/gwmr.12572
Autor:
Mattia Vitale, Cosimo Ligorio, Ian P. Smith, Stephen M. Richardson, Judith A. Hoyland, Jordi Bella
Publikováno v:
Gels, Vol 8, Iss 5, p 254 (2022)
Hydrogel biomaterials mimic the natural extracellular matrix through their nanofibrous ultrastructure and composition and provide an appropriate environment for cell–matrix and cell–cell interactions within their polymeric network. Hydrogels can
Externí odkaz:
https://doaj.org/article/b70fff686a1743f8a2151b3168257373
Autor:
Geoffrey H. Howarth, Beth Kahle, Philip E. Janney, Richard Kahle, Anton Du Plessis, Stephen H. Richardson, John J. Gurney
Publikováno v:
Geology. 51:532-536
Diamonds can form within eclogite (remnants of ancient subducted oceanic crust) in the subcontinental lithospheric mantle (SCLM), pieces of which may then be transported to the surface as xenoliths in kimberlites. These diamond-bearing xenoliths offe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::638c7aa79c8594b9e403853f019e9a0e
https://doi.org/10.1130/g51013.1
https://doi.org/10.1130/g51013.1