Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen A. Klautky"'
Publikováno v:
Journal of Biological Chemistry. 272:23606-23615
Glucagon, acting via cAMP, inhibits transcription of the malic enzyme gene in chick embryo hepatocytes. In transiently transfected hepatocytes, fragments from the 5'-flanking DNA of the malic enzyme gene confer cAMP responsiveness to linked reporter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7908c861414f2fabcd254e538347dc09
https://doi.org/10.1074/jbc.272.38.23606
https://doi.org/10.1074/jbc.272.38.23606
Publikováno v:
The Journal of Nutritional Biochemistry. 4:431-439
Nutritional state regulates the expression of many genes via alterations in the plasma levels of hormones or metabolic fuels. In many cases, transcription has been identified as the regulated step. The next objective in the experimental analysis of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db4cf27beb01ec6908f9949fbbb4ed44
https://doi.org/10.1016/0955-2863(93)90074-7
https://doi.org/10.1016/0955-2863(93)90074-7
Autor:
Alan G. Goodridge, Lisa M. Salati, David A. Mitchell, David S. Reinhold, Susan R. Stapleton, Stephen A. Klautky, Julian Swierczynski, Ann E. Struve
Publikováno v:
Journal of Biological Chemistry. 266:17459-17466
Addition of triiodothyronine (T3) to chick-embryo hepatocytes in culture causes increased accumulations of malic enzyme, fatty acid synthase, acetyl-CoA carboxylase and their mRNAs. H-8 and other protein kinase inhibitors inhibited the T3-induced acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::053147b4cb217a58017c24524700e569
https://doi.org/10.1016/s0021-9258(19)47395-x
https://doi.org/10.1016/s0021-9258(19)47395-x
Autor:
Stephen A. Klautky, S. E. Ash, David A. Mitchell, Xiao-Jun Ma, Dominic A. Fantozzi, Lisa M. Salati, Alan G. Goodridge
Publikováno v:
Journal of Biological Chemistry. 265:18435-18441
Refeeding starved chicks causes a 25- to 50-fold increase in the level of malic enzyme mRNA in liver. To define the regulated steps, we measured transcriptional activity of the malic enzyme gene using the nuclear run-on assay and a variety of DNA pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb23b5e3b96f5ad0cf8f02f6248acee7
https://doi.org/10.1016/s0021-9258(17)44771-5
https://doi.org/10.1016/s0021-9258(17)44771-5
Autor:
Stephen A. Klautky, Dominic Alexander Fantozzi, Alan G. Goodridge, Kathleen G. MacPhee, Gang Xu, Debbie C. Thurmond, Shawn T. Estrem, Dean W. Hodnett
Publikováno v:
Archives of biochemistry and biophysics. 334(2)
In vivo, feeding stimulates and starvation inhibits transcription of the malic enzyme gene. In chick-embryo hepatocytes in culture, triiodothyronine (T3) stimulates and glucagon inhibits transcription of this gene. As a first step in the characteriza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021dd93b4017495eb653e602548fb584
https://pubmed.ncbi.nlm.nih.gov/8900406
https://pubmed.ncbi.nlm.nih.gov/8900406
Publikováno v:
Archives of biochemistry and biophysics. 332(2)
The activity of glucose-6-phosphate dehydrogenase (G6PD) is inhibited by the addition of polyunsaturated fat (PUFA) to a high carbohydrate diet. To define the regulated step, we measured enzyme activity, accumulation of G6PD mRNA, and transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e406ae5d3516502e390286453042940
https://pubmed.ncbi.nlm.nih.gov/8806735
https://pubmed.ncbi.nlm.nih.gov/8806735
Autor:
Dean W. Hodnett, Stephen A. Klautky, Gang Xu, Alan G. Goodridge, Debbie C. Thurmond, Dominic A. Fantozzi, Rebecca Baillie, Weizu Chen, Cesar Roncero
Publisher Summary This chapter focuses on two lipogenic enzymes: malic enzyme and fatty-acid synthase. Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate, simultaneously generating NADPH from NADP + . Fatty-acid synthase is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae278329bb4e8b153c4a942183460828
https://doi.org/10.1016/s0079-6603(08)60965-4
https://doi.org/10.1016/s0079-6603(08)60965-4
Autor:
Stephen A. Klautky, Alan G. Goodridge, Cesareo Roncero, Lisa M. Salati, Xiao-Jun Ma, Dominic A. Fantozzi
Publikováno v:
The Proceedings of the Nutrition Society. 50(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43669a605d2aa19ac982aed4208ac805
https://pubmed.ncbi.nlm.nih.gov/1749785
https://pubmed.ncbi.nlm.nih.gov/1749785