Zobrazeno 1 - 10
of 1 061
pro vyhledávání: '"Stephen A. Johnson"'
Autor:
Alejandro Acien, Narghes Calcagno, Katherine M. Burke, Ijah Mondesire-Crump, Ashley A. Holmes, Sri Mruthik, Ben Goldy, Janina E. Syrotenko, Zoe Scheier, Amrita Iyer, Alison Clark, Mackenzie Keegan, Yoshiteru Ushirogawa, Atsushi Kato, Taku Yasuda, Amir Lahav, Satoshi Iwasaki, Mark Pascarella, Stephen A. Johnson, Teresa Arroyo-Gallego, James D. Berry
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative condition leading to progressive muscle weakness, atrophy, and ultimately death. Traditional ALS clinical evaluations often depend on subjective metrics, making accurate
Externí odkaz:
https://doaj.org/article/2498bc03479647a985a2b9a0dfe827ac
Autor:
Marta Karas, Julia Olsen, Marcin Straczkiewicz, Stephen A. Johnson, Katherine M. Burke, Satoshi Iwasaki, Amir Lahav, Zoe A. Scheier, Alison P. Clark, Amrita S. Iyer, Emily Huang, James D. Berry, Jukka‐Pekka Onnela
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 6, Pp 1380-1392 (2024)
Abstract Background Passively collected smartphone sensor data provide an opportunity to study physical activity and mobility unobtrusively over long periods of time and may enable disease monitoring in people with amyotrophic lateral sclerosis (PALS
Externí odkaz:
https://doaj.org/article/f72db7bc3351444789ad6d6fc4cde97e
Autor:
Marcin Straczkiewicz, Marta Karas, Stephen A. Johnson, Katherine M. Burke, Zoe Scheier, Tim B. Royse, Narghes Calcagno, Alison Clark, Amrita Iyer, James D. Berry, Jukka-Pekka Onnela
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105036- (2024)
Summary: Background: Objective evaluation of people with amyotrophic lateral sclerosis (PALS) in free-living settings is challenging. The introduction of portable digital devices, such as wearables and smartphones, may improve quantifying disease pro
Externí odkaz:
https://doaj.org/article/6d1dfa302d2f4761bdf2eabbe9a51d1f
Autor:
Stephen A. Johnson, Marta Karas, Katherine M. Burke, Marcin Straczkiewicz, Zoe A. Scheier, Alison P. Clark, Satoshi Iwasaki, Amir Lahav, Amrita S. Iyer, Jukka-Pekka Onnela, James D. Berry
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Amyotrophic lateral sclerosis (ALS) therapeutic development has largely relied on staff-administered functional rating scales to determine treatment efficacy. We sought to determine if mobile applications (apps) and wearable devices can be u
Externí odkaz:
https://doaj.org/article/02887f47e22d43be9f4f4f7017ac6466
Autor:
Katherine M. Burke, Amy S. Ellrodt, Benjamin C. Joslin, Pia P. Sanpitak, Claire MacAdam, Prabhav Deo, Kevin Ozment, Cristina Shea, Stephen A. Johnson, Doreen Ho, Samuel K. Chu, Ashwin N. Babu, Colin K. Franz, Sabrina Paganoni
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
IntroductionShoulder pain is a common secondary impairment for people living with ALS (PALS). Decreased range of motion (ROM) from weakness can lead to shoulder pathology, which can result in debilitating pain. Shoulder pain may limit PALS from parti
Externí odkaz:
https://doaj.org/article/9818e28e55384890807676e910ecc7dd
Ethanol causes and lithium prevents neuroapoptosis and suppression of pERK in the infant mouse brain
Publikováno v:
Neurobiology of Disease, Vol 31, Iss 3, Pp 355-360 (2008)
Transient exposure of immature animals during the brain growth spurt period to ethanol triggers neuroapoptosis in the developing brain. Here we report that lithium, when administered in a single, well-tolerated dose to infant mice, suppresses spontan
Externí odkaz:
https://doaj.org/article/fc103b4dfe374360866f5189ff34618e
Publikováno v:
Wind Energy, Vol 25, Iss 8, Pp 1313-1331 (2022)
Abstract Wind turbines have shown significant advancements in efficiency and power output in the last 20 years. However, during the same time period, parallel advances in the manufacturing of wind blades have not happened due to the reluctance of win
Externí odkaz:
https://doaj.org/article/8e2d496a2d0446429553164ae2eecd91
Autor:
Hyung Joo Lee, Yiran Hou, Yujie Chen, Zea Z. Dailey, Aiyana Riddihough, Hyo Sik Jang, Ting Wang, Stephen L. Johnson
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Zebrafish can faithfully regenerate injured fins through the formation of a blastema, a mass of proliferative cells that can grow and develop into the lost body part. After amputation, various cell types contribute to blastema for
Externí odkaz:
https://doaj.org/article/a438d34c3fa04731bcc8a4ba23b570bc
Autor:
Evgenii Belykh, Irakliy Abramov, Liudmila Bardonova, Ruchi Patel, Sarah McBryan, Lara Enriquez Bouza, Neil Majmundar, Xiaochun Zhao, Vadim A. Byvaltsev, Stephen A. Johnson, Amit Singla, Gaurav Gupta, Hai Sun, James K. Liu, Anil Nanda, Mark C. Preul, Michael T. Lawton
Publikováno v:
Journal of Neurosurgery. 138:732-739
OBJECTIVE Microsurgical training remains indispensable to master cerebrovascular bypass procedures, but simulation models for training that accurately replicate microanastomosis in narrow, deep-operating corridors are lacking. Seven simulation bypass
Publikováno v:
Journal of Evolutionary Biology. 36:550-562