Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Stephen A. Hoang"'
Autor:
Devin G. Roller, Stephen A. Hoang, Kristopher D. Rawls, Katherine A. Owen, Michael B. Simmers, Robert A. Figler, Julia D. Wulfkuhle, Emanuel F. Petricoin, Brian R. Wamhoff, Daniel Gioeli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Lung cancer rates are rising globally and non-small cell lung cancer (NSCLC) has a five year survival rate of only 24%. Unfortunately, the development of drugs to treat cancer is severely hampered by the inefficiency of translating pre-clini
Externí odkaz:
https://doaj.org/article/8c42edff85c244b88abc08fd238c4aa8
Autor:
Emma L. Shepherd, Raquel Saborano, Ellie Northall, Kae Matsuda, Hitomi Ogino, Hiroaki Yashiro, Jason Pickens, Ryan E. Feaver, Banumathi K. Cole, Stephen A. Hoang, Mark J. Lawson, Matthew Olson, Robert A. Figler, John E. Reardon, Nobuhiro Nishigaki, Brian R. Wamhoff, Ulrich L. Günther, Gideon Hirschfield, Derek M. Erion, Patricia F. Lalor
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100217- (2021)
Background & Aims: Increasing evidence highlights dietary fructose as a major driver of non-alcoholic fatty liver disease (NAFLD) pathogenesis, the majority of which is cleared on first pass through the hepatic circulation by enzymatic phosphorylatio
Externí odkaz:
https://doaj.org/article/4340ddc01197436fbd613f61ff255144
Autor:
Marty W. Mayo, Stefan Bekiranov, David R. Jones, Christopher A. Moskaluk, Xiaojiang Xu, Stephen A. Hoang, Szymon J. Szymura, Caitlyn M. Holzknecht, Sheena H. Clift, David F. Allison, Manish Kumar, J. Jacob Wamsley
Soluble growth factors and cytokines within the tumor microenvironment aid in the induction of the epithelial-to-mesenchymal transition (EMT). Although EMT promotes the development of cancer-initiating cells (CIC), cellular mechanisms by which cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267489785277719de60f9e138d406cd9
https://doi.org/10.1158/0008-5472.c.6505958
https://doi.org/10.1158/0008-5472.c.6505958
Autor:
Marty W. Mayo, Stefan Bekiranov, David R. Jones, Christopher A. Moskaluk, Xiaojiang Xu, Stephen A. Hoang, Szymon J. Szymura, Caitlyn M. Holzknecht, Sheena H. Clift, David F. Allison, Manish Kumar, J. Jacob Wamsley
Supplemental Table 1 and 2 and Supplemental Figure 1-5. Supplemental Table 1: Oligonucleotide sequences of shRNA molecules targeting INHBA/Activin and the targeted sequences. Supplemental Table 2: Oligonucleotide sequences used for amplification in Q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0543e0fa7d723617f81ee210cca2f259
https://doi.org/10.1158/0008-5472.22401968
https://doi.org/10.1158/0008-5472.22401968
Autor:
Brian A. Johns, Christin A. Hamilton, Allison J. Armstrong, Robert A. Figler, Maria Sol Collado, Taylor D. Pourtaheri, Brad R. Henke, Marshall M. Summar, Stephen A. Hoang, Kimberly A. Chapman, John E. Reardon, Brian R. Wamhoff, Matthew W. Olson
Publikováno v:
Mol Genet Metab
Propionic Acidemia (PA) and Methylmalonic Acidemia (MMA) are inborn errors of metabolism affecting the catabolism of valine, isoleucine, methionine, threonine and odd-chain fatty acids. These are multi-organ disorders caused by the enzymatic deficien
Autor:
Brian R. Wamhoff, Daniel Gioeli, Devin G. Roller, Kristopher D. Rawls, Katherine A. Owen, Emanuel F. Petricoin, Julia Wulfkuhle, Stephen A. Hoang, Robert A. Figler, Michael B. Simmers
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Lung cancer rates are rising globally and non-small cell lung cancer (NSCLC) has a five year survival rate of only 24%. Unfortunately, the development of drugs to treat cancer is severely hampered by the inefficiency of translating pre-clinical studi
Autor:
Nathan Day, Brian R. Wamhoff, Matthew Olson, Marshall L. Summar, Allison J. Armstrong, Stephen A. Hoang, Robert A. Figler, M. Sol Collado, John E. Reardon, Kimberly A. Chapman
Publikováno v:
Mol Genet Metab
Propionic acidemia (PA) and methylmalonic acidemia (MMA) are autosomal recessive disorders of propionyl-CoA (P-CoA) catabolism, which are caused by a deficiency in the enzyme propionyl-CoA carboxylase or the enzyme methylmalonyl-CoA (MM-CoA) mutase,
Autor:
John E Dillberger, Thomas D Roper, Allison J. Armstrong, Brian R. Wamhoff, Stephen A. Hoang, Matthew W. Olson, Justin M. Taylor, Brad R. Henke, John E. Reardon, Maria Sol Collado, Brian A. Johns, Robert A. Figler, Taylor D. Pourtaheri
Publikováno v:
Journal of medicinal chemistry. 64(8)
Propionic acidemia (PA) and methylmalonic acidemia (MMA) are rare autosomal recessive disorders of propionyl-CoA (P-CoA) catabolism, caused by a deficiency in the enzymes P-CoA carboxylase and methylmalonyl-CoA (M-CoA) mutase, respectively. PA and MM
Autor:
Ellie Northall, Banumathi K. Cole, John E. Reardon, Brian R. Wamhoff, Matthew W. Olson, Stephen A. Hoang, Kae Matsuda, Ulrich L. Günther, Mark J. Lawson, Ryan E. Feaver, Jason Pickens, Patricia F. Lalor, Raquel Saborano, Robert A. Figler, Hiroaki Yashiro, Derek M. Erion, Hitomi Ogino, Emma L. Shepherd, Gideon M. Hirschfield, Nobuhiro Nishigaki
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100217-(2021)
JHEP Reports
JHEP Reports
Background & Aims Increasing evidence highlights dietary fructose as a major driver of non-alcoholic fatty liver disease (NAFLD) pathogenesis, the majority of which is cleared on first pass through the hepatic circulation by enzymatic phosphorylation
Autor:
Stephen A Hoang, Stefan Bekiranov
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81972 (2013)
We propose a network-based approach for surmising the spatial organization of genomes from high-throughput interaction data. Our strategy is based on methods for inferring architectural features of networks. Specifically, we employ a community detect
Externí odkaz:
https://doaj.org/article/3bb6544a354348ddb5410c5b4176d392