Zobrazeno 1 - 10
of 737
pro vyhledávání: '"Stephen A. Boppart"'
Autor:
Janet E. Sorrells, Jaena Park, Edita Aksamitiene, Marina Marjanovic, Elisabeth M. Martin, Eric J. Chaney, Anna M. Higham, Kimberly A. Cradock, Zheng G. Liu, Stephen A. Boppart
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Extracellular vesicles (EVs) have been implicated in metastasis and proposed as cancer biomarkers. However, heterogeneity and small size makes assessments of EVs challenging. Often, EVs are isolated from biofluids, losing spatial and tempora
Externí odkaz:
https://doaj.org/article/f992f4ae78044221a9dce8ad58282b4c
Autor:
Rishyashring R. Iyer, Lingxiao Yang, Janet E. Sorrells, Eric J. Chaney, Darold R. Spillman Jr., Stephen A. Boppart
Publikováno v:
APL Photonics, Vol 9, Iss 7, Pp 076114-076114-16 (2024)
The applications of ultrafast optics to biomedical microscopy have expanded rapidly in recent years, including interferometric techniques like optical coherence tomography and microscopy (OCT/OCM). The advances of ultra-high resolution OCT and the in
Externí odkaz:
https://doaj.org/article/6f3e61206c2a4f709e0efb15db0ccb58
Autor:
Kajari Bera, Renán A. Rojas-Gómez, Prabuddha Mukherjee, Corey E. Snyder, Edita Aksamitiene, Aneesh Alex, Darold R. Spillman, Marina Marjanovic, Ahmed Shabana, Russell Johnson, Steve R. Hood, Stephen A. Boppart
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The COVID-19 pandemic triggered the resurgence of synthetic RNA vaccine platforms allowing rapid, scalable, low-cost manufacturing, and safe administration of therapeutic vaccines. Self-amplifying mRNA (SAM), which self-replicates upon deliv
Externí odkaz:
https://doaj.org/article/9fc1328809a0480cb6006ae1bf4fb049
Autor:
Terrence T. Roh, Aneesh Alex, Prasanna M. Chandramouleeswaran, Janet E. Sorrells, Alexander Ho, Rishyashring R. Iyer, Darold R. Spillman, Jr., Marina Marjanovic, Jason E. Ekert, BanuPriya Sridharan, Balabhaskar Prabhakarpandian, Steve R. Hood, Stephen A. Boppart
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103280- (2024)
The DNA damage response (DDR) is a fundamental readout for evaluating efficacy of cancer therapeutics, many of which target DNA associated processes. Current techniques to evaluate DDR rely on immunostaining for phosphorylated histone H2AX (γH2AX),
Externí odkaz:
https://doaj.org/article/f2e4f48cd93a4b6196f8b2536ff8af15
Autor:
Jaena Park, Janet E. Sorrells, Eric J. Chaney, Amro M. Abdelrahman, Jennifer A. Yonkus, Jennifer L. Leiting, Heidi Nelson, Jonathan J. Harrington, Edita Aksamitiene, Marina Marjanovic, Peter D. Groves, Colleen Bushell, Mark J. Truty, Stephen A. Boppart
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Pancreatic cancer is a devastating disease often detected at later stages, necessitating swift and effective chemotherapy treatment. However, chemoresistance is common and its mechanisms are poorly understood. Here, label-free multi-modal no
Externí odkaz:
https://doaj.org/article/caa8ab88d08344c5ae72a4306c96e8da
Publikováno v:
Translational Biophotonics, Vol 5, Iss 3-4, Pp n/a-n/a (2023)
Abstract We analyzed ophthalmic retinal optical coherence tomography (OCT) images from patients with Alzheimer's disease (AD) to identify retinal layer thickness and ratio changes that may serve as image‐based biomarkers for the disease. One three
Externí odkaz:
https://doaj.org/article/1ac9910c9b9e44d5a678bad6d9e0f49b
Autor:
Weinan Zhou, Philip VanDuyne, Chi Zhang, Yushan Liu, Ryan Riessen, Maribel Barragan, Blair M. Rowitz, Margarita Teran-Garcia, Stephen A. Boppart, Sayeepriyadarshini Anakk
Publikováno v:
JHEP Reports, Vol 5, Iss 5, Pp 100714- (2023)
Background & Aims: Although fat loss is observed in patients with cholestasis, how chronically elevated bile acids (BAs) impact white and brown fat depots remains obscure. Methods: To determine the direct effect of pathological levels of BAs on lipid
Externí odkaz:
https://doaj.org/article/3d857a80725c4928a5fb0e56fedb1c98
Autor:
Rishyashring R. Iyer, Janet E. Sorrells, Lingxiao Yang, Eric J. Chaney, Darold R. Spillman, Brian E. Tibble, Carlos A. Renteria, Haohua Tu, Mantas Žurauskas, Marina Marjanovic, Stephen A. Boppart
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Label-free optical microscopy has matured as a noninvasive tool for biological imaging; yet, it is criticized for its lack of specificity, slow acquisition and processing times, and weak and noisy optical signals that lead to inaccuracies in
Externí odkaz:
https://doaj.org/article/b3bf0c28b91e4f818ade00ca9b92555c
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 16, Iss 01 (2023)
Nonlinear optical imaging is a versatile tool that has been proven to be exceptionally useful in various research fields. However, due to the use of photomultiplier tubes (PMTs), the wide application of nonlinear optical imaging is limited by the inc
Externí odkaz:
https://doaj.org/article/c70182bc009246afb504b1d72f065115
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-7 (2021)
Abstract Polarization-sensitive optical coherence tomography (PS-OCT) is a high-resolution label-free optical biomedical imaging modality that is sensitive to the microstructural architecture in tissue that gives rise to form birefringence, such as c
Externí odkaz:
https://doaj.org/article/a5bc8ef4638c4706a63612db7ea60cc4