Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stephen A. Alsdorf"'
Publikováno v:
Experimental Neurology. 167:196-204
Excitotoxic lesions of the striatum are mediated by the combined activity of N-methyl-d-aspartate (NMDA) receptors and metabotropic glutamate receptors (mGluRs). Intrastriatal injection of the NMDA receptor agonists NMDA or quinolinic acid creates la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e654e43aa1be0e950d07e84cc3de55
https://doi.org/10.1006/exnr.2000.7542
https://doi.org/10.1006/exnr.2000.7542
Autor:
John B. Penney, Jang-Ho J. Cha, Christoph M. Kosinski, Gillian P. Bates, Anne B. Young, J A Kerner, Stephen W. Davies, Laura Mangiarini, Stephen A. Alsdorf
Publikováno v:
Proceedings of the National Academy of Sciences. 95:6480-6485
Loss of neurotransmitter receptors, especially glutamate and dopamine receptors, is one of the pathologic hallmarks of brains of patients with Huntington disease (HD). Transgenic mice that express exon 1 of an abnormal human HD gene (line R6/2) devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e287c382f0a82bfc5fc51c3d012b2cb
https://doi.org/10.1073/pnas.95.11.6480
https://doi.org/10.1073/pnas.95.11.6480
Autor:
Anne B. Young, Christoph M. Kosinski, Gillian P. Bates, J A Kerner, Jang-Ho J. Cha, John B. Penney, Stephen A. Alsdorf, Ariel S. Frey, Stephen W. Davies, Laura Mangiarini
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 354(1386)
Alterations in neurotransmitter receptors are a pathological hallmark of the neurodegeneration seen in Huntington's disease (HD). However, the significance of these alterations has been uncertain, possibly reflecting simply the loss of brain cells. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cac06db322dc70f3084f89275b74f6
https://pubmed.ncbi.nlm.nih.gov/10434296
https://pubmed.ncbi.nlm.nih.gov/10434296