Zobrazeno 1 - 10
of 481
pro vyhledávání: '"Stephen A. Wise"'
Autor:
Alana D. Carpenter, Keirstyn M. Empfield, Sarah A. Petrus, Oluseyi O. Fatanmi, Stephen Y. Wise, John B. Tyburski, Amrita K. Cheema, Vijay K. Singh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Exposure to ionizing radiation induces cellular and molecular damage leading to a cascade of events resulting in tissue and organ injury. Our study strives to characterize and validate metabolomic changes in preterminal stage (immediately pr
Externí odkaz:
https://doaj.org/article/d4401c716e9e4266ab0d2bd292060434
Autor:
Alana D. Carpenter, Oluseyi O. Fatanmi, Stephen Y. Wise, John B. Tyburski, Amrita K. Cheema, Vijay K. Singh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The identification and validation of radiation biomarkers is critical for assessing the radiation dose received in exposed individuals and for developing radiation medical countermeasures that can be used to treat acute radiation syndrome (A
Externí odkaz:
https://doaj.org/article/2f344ce7dbcf4ad594ec6e0c5dfd951e
Autor:
Vijay K. Singh, Stephen Y. Wise, Oluseyi O. Fatanmi, Sarah A. Petrus, Alana D. Carpenter, Luis A. Lugo-Roman, Sang-Ho Lee, Martin Hauer-Jensen, Thomas M. Seed
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Exposure to high, marginally lethal doses or higher of ionizing radiation, either intentional or accidental, results in injury to various organs. Currently, there is only a limited number of safe and effective radiation countermeasures appro
Externí odkaz:
https://doaj.org/article/7999739a1f334afbb30bb3fc9099f192
Autor:
Vijay K. Singh, Stephen Y. Wise, Oluseyi O. Fatanmi, Sarah A. Petrus, Alana D. Carpenter, Sang-Ho Lee, Martin Hauer-Jensen, Thomas M. Seed
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Despite remarkable scientific progress over the past six decades within the medical arts and in radiobiology in general, limited radiation medical countermeasures (MCMs) have been approved by the United States Food and Drug Administration fo
Externí odkaz:
https://doaj.org/article/223d81ad7fec4cca8af5b9fc9fd4910e
Autor:
Eric Russ, Oluseyi O. Fatanmi, Stephen Y. Wise, Alana D. Carpenter, Manoj Maniar, Sergey Iordanskiy, Vijay K. Singh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Exposure to ionizing radiation (IR) presents a formidable clinical challenge. Total-body or significant partial-body exposure at a high dose and dose rate leads to acute radiation syndrome (ARS), the complex pathologic effects that arise fol
Externí odkaz:
https://doaj.org/article/f8b341f1621c4f83a95e9eda4d72246c
Autor:
Nabarun Chakraborty, George Dimitrov, Swapna Kanan, Alexander Lawrence, Candance Moyler, Aarti Gautam, Oluseyi O Fatanmi, Stephen Y Wise, Alana D Carpenter, Rasha Hammamieh, Vijay K Singh
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0311379 (2024)
Multiple accidents in nuclear power plants and the growing concerns about the misuse of radiation exposure in warfare have called for the rapid determination of absorbed radiation doses (RDs). The latest findings about circulating microRNA (miRNAs) u
Externí odkaz:
https://doaj.org/article/b3572931517d4e53aede2a1b9c530b5a
Autor:
Neetha Nanoth Vellichirammal, Sahil Sethi, Nagavardhini Avuthu, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Chittibabu Guda, Vijay K. Singh
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract The risk of exposure of the general public or military personnel to high levels of ionizing radiation from nuclear weapons or radiological accidents is a dire national security matter. The development of advanced molecular biodosimetry metho
Externí odkaz:
https://doaj.org/article/99c4a7b85d414c0bbcf85c39bfb8bbfe
Autor:
Neetha Nanoth Vellichirammal, Sahil Sethi, Sanjit Pandey, Jatinder Singh, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Chittibabu Guda, Vijay K. Singh
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 584-598 (2022)
The focus of radiation biodosimetry has changed recently, and a paradigm shift for using molecular technologies of omic platforms in addition to cytogenetic techniques has been observed. In our study, we have used a nonhuman primate model to investig
Externí odkaz:
https://doaj.org/article/dbd5bc15b1e7407598bea42cda0e0d55
Autor:
Alana D. Carpenter, Oluseyi O. Fatanmi, Stephen Y. Wise, Sarah A. Petrus, John B. Tyburski, Amrita K. Cheema, Vijay K. Singh
Publikováno v:
Metabolites, Vol 14, Iss 1, p 18 (2023)
Ionizing radiation exposure is known to induce molecular and cellular injury, inflicting a cascade of potentially catastrophic events leading to tissue and organ damage. Metabolomic analysis allows for the identification and quantification of small m
Externí odkaz:
https://doaj.org/article/a497c6d777884b7683fb9bf3e28ab283
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Radiological incidents or terrorist attacks would likely expose civilians and military personnel to high doses of ionizing radiation, leading to the development of acute radiation syndrome. We examined the effectiveness of prophylactic admin
Externí odkaz:
https://doaj.org/article/3b3a541504f14eab834bc32124712a7e