Zobrazeno 1 - 10 of 42 pro vyhledávání: '"Stephen A Stimpson"'
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Akademický článek
Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility.
Autor: Shian-Huey Chiang, W Wallace Harrington, Guizhen Luo, Naphtali O Milliken, John C Ulrich, Jing Chen, Deepak K Rajpal, Ying Qian, Tiffany Carpenter, Rusty Murray, Robert S Geske, Stephen A Stimpson, Henning F Kramer, Curt D Haffner, J David Becherer, Frank Preugschat, Andrew N Billin
Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0134927 (2015)
Nicotinamide adenine dinucleotide (NAD+) is a key cofactor required for essential metabolic oxidation-reduction reactions. It also regulates various cellular activities, including gene expression, signaling, DNA repair and calcium homeostasis. Intrac
Externí odkaz: https://doaj.org/article/6c250288d3cf48f0b41fe25918c4ad63
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2
Total body skeletal muscle mass estimated by magnetic resonance imaging and creatine (methyl‐d3) dilution in athletes
Autor: Tessa Eleri Morris-Paterson, Michael S. Leonard, Owen Carmichael, Matthew E. Barton, Stephen D. R. Harridge, Ken A. van Someren, Ram R. Miller, Stephen A. Stimpson
Publikováno v: Morris-Paterson, T E, Stimpson, S A, Miller, R R, Barton, M E, Leonard, M S, Carmichael, O, van Someren, K A & Harridge, S D R 2019, ' Total body skeletal muscle mass estimated by Magnetic Resonance Imaging and creatine ( methyl-d3 ) dilution in athletes ', Scandinavian Journal of Medicine and Science in Sports . https://doi.org/10.1111/sms.13585
Creatine dilution (D 3-cr) is a technique for estimating total skeletal muscle mass (SMM) with practical utility, but has not been applied in athletic populations where body composition may differ to that in the normal population. This study aimed to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a00eb28d0688040645d8c14431c5883
https://doi.org/10.1111/sms.13585
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Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats
Autor: Stephen A. Stimpson, Todd W. Shearer, Fritz Kramer, Ying Shen, Marc K. Hellerstein, Chelsea King, Po-yin Anne Wong, Mahalakshmi Shankaran, Alan J. Russell, Philip Stewart Turnbull, William J. Evans, Lisa G. Clifton, Scott M. Turner
Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 310:E405-E417
Biomarkers of muscle protein synthesis rate could provide early data demonstrating anabolic efficacy for treating muscle-wasting conditions. Androgenic therapies have been shown to increase muscle mass primarily by increasing the rate of muscle prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e98cabc9523eeeb5b539e53992008e
https://doi.org/10.1152/ajpendo.00257.2015
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4
Small Molecule Mediated Intervention of NF-kB or TGF-β Signaling Reverses Age-Related Phenotypes in Satellite Cells and Enhances Muscle Repair
Autor: Lauren R. Sheckler, Irving L. Weissman, Stephen A. Stimpson, Massimiliano Cerletti, Joshua J. Schroeder, Amy J. Wagers, John T. Moore, Matthew A. Inlay, Tata Nageswara Rao, Dave J. Becherer, Derrick J. Rossi, Tsu T. Chuang, Deepti A. Cole
Publikováno v: SSRN Electronic Journal.
Skeletal muscle normally exhibits robust regenerative potential in youth; however, myogenic activity declines with age, resulting in defective muscle repair after injury. In this study, we identified signaling pathways in mouse muscle stem cells that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb09ee48d13552e4d63a0315a8951b12
https://doi.org/10.2139/ssrn.3244794
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Dramatic elevation in urinary amino terminal titin fragment excretion quantified by immunoassay in Duchenne muscular dystrophy patients and in dystrophin deficient rodents
Autor: Janet DiPiero, Glen B. Banks, Leslie K. Jacobsen, Nino Devidze, Denise Bounous, Linda J. Bristow, Stephen A. Stimpson, Sean C. Little, Michael K. Ahlijanian, Robert C. Gagnon, Courtney M. Smith, Mark J. Majchrzak, Alan S. Robertson, Fizal Nabbie
Publikováno v: Neuromuscular disorders : NMD. 27(7)
Enzyme-linked and electrochemiluminescence immunoassays were developed for quantification of amino (N-) terminal fragments of the skeletal muscle protein titin (N-ter titin) and qualified for use in detection of urinary N-ter titin excretion. Urine f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00dd2f31cd418e94fcc888a18148027a
https://pubmed.ncbi.nlm.nih.gov/28554556
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6
Total body skeletal muscle mass: estimation by creatine (methyl-d3) dilution in humans
Autor: Scott M. Turner, Richard V. Clark, Eric Ravussin, Stephen A. Stimpson, William T. Cefalu, William J. Evans, Ram Miller, Robin L. O'Connor-Semmes, Ann C. Walker, Marc K. Hellerstein, Michael S. Leonard
Publikováno v: Journal of Applied Physiology. 116:1605-1613
Current methods for clinical estimation of total body skeletal muscle mass have significant limitations. We tested the hypothesis that creatine ( methyl-d3) dilution (D3-creatine) measured by enrichment of urine D3-creatinine reveals total body creat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa181525b4ff8c5044210b7f22770448
https://doi.org/10.1152/japplphysiol.00045.2014
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7
Post-transcriptional regulation of ITGB6 protein levels in damaged skeletal muscle
Autor: Stephen A. Stimpson, Lisa G. Clifton, Andrew N. Billin, Melissa Ducceschi
Publikováno v: Journal of Molecular Histology
We have identified integrin beta 6 (Itgb6) as a transcript highly enriched in skeletal muscle. This finding is unexpected because Itgb6 is typically associated with epithelial expression domains in normal tissue. Further we find that ITGB6 protein ex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb033a055bb1e0793b57395b876fe970
http://europepmc.org/articles/PMC3983900
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8
Longitudinal changes in total body creatine pool size and skeletal muscle mass using the D3-creatine dilution method
Autor: Stephen A. Stimpson, Lisa G. Clifton, Richard V. Clark, Marc K. Hellerstein, Katja Remlinger, Todd W. Shearer, Scott M. Turner, Michael S. Leonard, James C. Poole, William J. Evans
Publikováno v: Journal of Cachexia, Sarcopenia and Muscle
Background We recently validated in cross-sectional studies a new method to determine total body creatine pool size and skeletal muscle mass based on D3-creatine dilution from an oral dose and detection of urinary creatinine enrichment by isotope rat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682ae04d10a4cc672c85a86881d715c5
https://doi.org/10.1007/s13539-013-0110-1
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9
Effectiveness of the PPARγ agonist, GW570, in liver fibrosis
Autor: Don C. Rockey, Liu Yang, Stephen A. Stimpson, Lihong Chen, W. Wallace Harrington
Publikováno v: Inflammation Research. 59:1061-1071
Introduction The peroxisome proliferator-activated receptors (PPARs) are well established to be important in modulating the fibrogenic response to liver injury. PPARγ plays a role in hepatic fibrosis, presumably by virtue of its expression in hepati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cad171352bfb6115d3c70f4938472a
https://doi.org/10.1007/s00011-010-0226-0
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