Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Stephen A Schworer"'
Race-specific spirometry equations may overestimate asthma control in Black children and adolescents
Autor:
Allison J. Burbank, Claire E. Atkinson, Andre E. Espaillat, Stephen A. Schworer, Katherine Mills, Jennifer Rooney, Ceila E. Loughlin, Wanda Phipatanakul, Michelle L. Hernandez
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-5 (2023)
Abstract Background A growing body of evidence suggests that use of race terms in spirometry reference equations underestimates disease burden in Black populations, which may lead to disparities in pulmonary disease outcomes. Data on asthma-specific
Externí odkaz:
https://doaj.org/article/5c8603b6f84641c6876e10118a4fcb8b
ANCA vasculitis expands the spectrum of autoimmune manifestations of activated PI3 kinase δ syndrome
Autor:
Amika K. Sood, Olivia Francis, Stephen A. Schworer, Steven M. Johnson, Benjamin D. Smith, Paul B. Googe, Eveline Y. Wu
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Activated phosphoinositide 3-kinase δ syndrome (APDS) is a combined immunodeficiency with a broad clinical phenotype, including not only an increased propensity for sinopulmonary and herpesviruses infections but also immune dysregulation, such as be
Externí odkaz:
https://doaj.org/article/2ba2c8a666004f18bcd4953da2fd21c4
Autor:
Allison J. Burbank, Stephen A. Schworer, Amika Sood, Martha Almond, Kelly Chason, Nathan Bean, Haibo Zhou, Michelle L. Hernandez
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-4 (2021)
Abstract Background Preclinical studies implicate interleukin (IL)-1β as a key mediator of asthma and have shown the efficacy of IL-1 antagonism for treatment of allergic airway inflammation; human studies in this area are lacking. Objectives Our ai
Externí odkaz:
https://doaj.org/article/bee16752aea946cb9db280a2de106cc2
Autor:
Xiaomei Kong, William C. Bennett, Corey M. Jania, Kelly D. Chason, Zachary German, Jennifer Adouli, Samuel D. Budney, Brandon T. Oby, Catharina van Heusden, Eduardo R. Lazarowski, Ilona Jaspers, Scott H. Randell, Barry A. Hedgespeth, Glenn Cruse, Xiaoyang Hua, Stephen A. Schworer, Gregory J. Smith, Samir N.P. Kelada, Stephen L. Tilley
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Ozone is a highly reactive environmental pollutant with well-recognized adverse effects on lung health. Bronchial hyperresponsiveness (BHR) is one consequence of ozone exposure, particularly for individuals with underlying lung disease. Our data demo
Externí odkaz:
https://doaj.org/article/226737900b334c5cb82e39193a8ffaf5
Autor:
Hayley I. Muendlein, Joseph Sarhan, Beiyun C. Liu, Wilson M. Connolly, Stephen A. Schworer, Irina Smirnova, Amy Y. Tang, Vladimir Ilyukha, Jodie Pietruska, Soroush Tahmasebi, Nahum Sonenberg, Alexei Degterev, Alexander Poltorak
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 699-713.e4 (2020)
Summary: Receptor-interacting protein kinase 1 (RIPK1) and 3 (RIPK3) are well known for their capacity to drive necroptosis via mixed-lineage kinase-like domain (MLKL). Recently, RIPK1/3 kinase activity has been shown to drive inflammation via activa
Externí odkaz:
https://doaj.org/article/b14db846e8cc4f8c8f65d98ff6c63481
Autor:
Stephen A. Schworer, Kelly D. Chason, Gang Chen, Jie Chen, Haibo Zhou, Allison J. Burbank, Matthew J. Kesic, Michelle L. Hernandez
Publikováno v:
Journal of Allergy and Clinical Immunology.
Autor:
Roy A. Pleasants, Amy HY. Chan, Giselle Mosnaim, Richard W. Costello, Rajiv Dhand, Stephen A. Schworer, Rajan Merchant, Stephen L. Tilley
Publikováno v:
Respiratory medicine. 205
Modernizing inhaled medications through digital technology can help address persistent problems of non-adherence and poor inhaler technique in patients with obstructive lung diseases. With a growing body of supportive clinical studies, advances in di
Publikováno v:
Clinical Reviews in Allergy & Immunology. 62:413-431
Biologic medications are an expanding field of therapeutics for various medical conditions including cancer and inflammatory diseases. Due to their targeted approach to therapy, biologics can be less toxic than traditional systemic medications. Howev
Autor:
Claire E. Atkinson, Stephen A. Schworer, Kate Matthews, Katherine Mills, Katherine Neighbors, Allison J. Burbank, Michelle L. Hernandez
Publikováno v:
The journal of allergy and clinical immunology. In practice. 10(10)
Autor:
Vladimir Ilyukha, Alexei Degterev, Wilson M. Connolly, Hayley I. Muendlein, Beiyun C. Liu, Nahum Sonenberg, Jodie R. Pietruska, Alexander Poltorak, Stephen A Schworer, Amy Y. Tang, Irina Smirnova, Joseph Sarhan, Soroush Tahmasebi
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 699-713.e4 (2020)
Cell reports
Cell reports
SUMMARY Receptor-interacting protein kinase 1 (RIPK1) and 3 (RIPK3) are well known for their capacity to drive necroptosis via mixed-lineage kinase-like domain (MLKL). Recently, RIPK1/3 kinase activity has been shown to drive inflammation via activat