Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Stephen A Goldstein"'
Autor:
Sarah M Fixsen, Kelsey R Cone, Stephen A Goldstein, Thomas A Sasani, Aaron R Quinlan, Stefan Rothenburg, Nels C Elde
Publikováno v:
eLife, Vol 11 (2022)
Horizontal gene transfer (HGT) provides a major source of genetic variation. Many viruses, including poxviruses, encode genes with crucial functions directly gained by gene transfer from hosts. The mechanism of transfer to poxvirus genomes is unknown
Externí odkaz:
https://doaj.org/article/aadc30f9671040cdbafe9e15f415e1f5
Autor:
Yize Li, Shuvojit Banerjee, Stephen A Goldstein, Beihua Dong, Christina Gaughan, Sneha Rath, Jesse Donovan, Alexei Korennykh, Robert H Silverman, Susan R Weiss
Publikováno v:
eLife, Vol 6 (2017)
ADAR1 isoforms are adenosine deaminases that edit and destabilize double-stranded RNA reducing its immunostimulatory activities. Mutation of ADAR1 leads to a severe neurodevelopmental and inflammatory disease of children, Aicardi-Goutiéres syndrome.
Externí odkaz:
https://doaj.org/article/10892b8d0012417b8d9719dca9a847cd
Autor:
Stephen A. Goldstein, Nels C. Elde
Phosphodiesterases (PDEs) encoded by nidoviruses and rotaviruses (RVs) promote viral replication and pathogenesis. Putatively acquired by horizontal transfer of cellular PDE ancestor genes, viral PDEs inhibit the OAS-RNase L antiviral pathway, a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afd872827a317741ac86befb2bfeead1
https://doi.org/10.1101/2023.05.12.540623
https://doi.org/10.1101/2023.05.12.540623
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in 2012 as a novel etiological agent of severe respiratory disease in humans. As during infection by other viruses, host sensing of viral double-stranded RNA (dsRNA
Externí odkaz:
https://doaj.org/article/0a97ea3667ad408cb830e467533a9db1
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
The ongoing SARS-CoV-2 pandemic is the third zoonotic coronavirus identified in the last twenty years. Previously, four other known coronaviruses moved from animal reservoirs into humans and now cause primarily mild-to-moderate respiratory disease. T
Autor:
Michael Worobey, Joshua I. Levy, Lorena Malpica Serrano, Alexander Crits-Christoph, Jonathan E. Pekar, Stephen A. Goldstein, Angela L. Rasmussen, Moritz U. G. Kraemer, Chris Newman, Marion P. G. Koopmans, Marc A. Suchard, Joel O. Wertheim, Philippe Lemey, David L. Robertson, Robert F. Garry, Edward C. Holmes, Andrew Rambaut, Kristian G. Andersen
Publikováno v:
Science, 377(6609), 951-959. American Association for the Advancement of Science
Science (New York, N.Y.), vol 377, iss 6609
Worobey, M, Levy, J I, Malpica Serrano, L, Crits-Christoph, A, Pekar, J E, Goldstein, S A, Rasmussen, A L, Kraemer, M U G, Newman, C, Koopmans, M P G, Suchard, M A, Wertheim, J O, Lemey, P, Robertson, D L, Garry, R F, Holmes, E C, Rambaut, A & Andersen, K G 2022, ' The Huanan seafood wholesale market in Wuhan was the early epicenter of the COVID-19 pandemic ', Science, vol. 377, no. 6609, pp. 951-959 . https://doi.org/10.1126/science.abp8715
Science (New York, N.Y.), vol 377, iss 6609
Worobey, M, Levy, J I, Malpica Serrano, L, Crits-Christoph, A, Pekar, J E, Goldstein, S A, Rasmussen, A L, Kraemer, M U G, Newman, C, Koopmans, M P G, Suchard, M A, Wertheim, J O, Lemey, P, Robertson, D L, Garry, R F, Holmes, E C, Rambaut, A & Andersen, K G 2022, ' The Huanan seafood wholesale market in Wuhan was the early epicenter of the COVID-19 pandemic ', Science, vol. 377, no. 6609, pp. 951-959 . https://doi.org/10.1126/science.abp8715
Understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in 2019 is critical to preventing future zoonotic outbreaks before they become the next pandemic. The Huanan Seafood Wholesale Market in Wuhan, China, was identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51645080386d894af5e84ed5f116e518
https://pure.eur.nl/en/publications/5c94d416-934c-4d7f-825d-dea3e38c9099
https://pure.eur.nl/en/publications/5c94d416-934c-4d7f-825d-dea3e38c9099
Autor:
Elizabeth J. Fay, Keir M. Balla, Shanley N. Roach, Frances K. Shepherd, Dira S. Putri, Talia D. Wiggen, Stephen A. Goldstein, Mark J. Pierson, Martin T. Ferris, Claire E. Thefaine, Andrew Tucker, Mark Salnikov, Valerie Cortez, Susan R. Compton, Sergei V. Kotenko, Ryan C. Hunter, David Masopust, Nels C. Elde, Ryan A. Langlois
Publikováno v:
The Journal of experimental medicine, vol 219, iss 2
Emerging viruses threaten global health, but few experimental models can characterize the virus and host factors necessary for within- and cross-species transmission. Here, we leverage a model whereby pet store mice or rats—which harbor natural rod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90035b8476ecd46c6b00c7c9729ffc5
https://escholarship.org/uc/item/5t8270hs
https://escholarship.org/uc/item/5t8270hs
Autor:
Joshua M. Thornbrough, Babal K. Jha, Boyd Yount, Stephen A. Goldstein, Yize Li, Ruth Elliott, Amy C. Sims, Ralph S. Baric, Robert H. Silverman, Susan R. Weiss
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) is the first highly pathogenic human coronavirus to emerge since severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002. Like many coronaviruses, MERS-CoV carries genes that e
Externí odkaz:
https://doaj.org/article/bc4737fc08994557a29b4ee680bbd0de
Autor:
Kristian G. Andersen, Andrew Rambaut, Jeremy Farrar, Angela L. Rasmussen, Tim Skern, Susan R. Weiss, Jemma L. Geoghegan, Alexander Crits-Christoph, Michael Worobey, Xiaowei Jiang, David Robertson, Robert F. Garry, Wendy S. Barclay, Stuart J. D. Neil, Stephen A. Goldstein, Edward C. Holmes, Peter C. Doherty, Maciej F. Boni, Joel O. Wertheim, Julian L. Leibowitz, Simon J. Anthony
Publikováno v:
Cell
Holmes, E C, Goldstein, S A, Rasmussen, A L, Robertson, D L, Crits-Christoph, A, Wertheim, J O, Anthony, S J, Barclay, W S, Boni, M F, Doherty, P C, Farrar, J, Geoghegan, J L, Jiang, X, Leibowitz, J L, Neil, S J D, Skern, T, Weiss, S R, Worobey, M, Andersen, K G, Garry, R F & Rambaut, A 2021, ' The origins of SARS-CoV-2 : A critical review ', Cell, vol. 184, no. 19, pp. 4848-4856 . https://doi.org/10.1016/j.cell.2021.08.017
Cell, vol 184, iss 19
Holmes, E C, Goldstein, S A, Rasmussen, A L, Robertson, D L, Crits-Christoph, A, Wertheim, J O, Anthony, S J, Barclay, W S, Boni, M F, Doherty, P C, Farrar, J, Geoghegan, J L, Jiang, X, Leibowitz, J L, Neil, S J D, Skern, T, Weiss, S R, Worobey, M, Andersen, K G, Garry, R F & Rambaut, A 2021, ' The origins of SARS-CoV-2 : A critical review ', Cell, vol. 184, no. 19, pp. 4848-4856 . https://doi.org/10.1016/j.cell.2021.08.017
Cell, vol 184, iss 19
The Origins of SARS-CoV-2: A Critical Review Holmes et al. Published online: 18-Aug-2021, Cell, https://doi.org/10.1016/j.cell.2021.08.017 Since the first reports of a novel SARS-like coronavirus in December 2019 in Wuhan, China, there has been inten