Zobrazeno 1 - 10
of 408
pro vyhledávání: '"Stephen A Goff"'
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115740 (2014)
Sequencing the transcriptome can answer various questions such as determining the transcripts expressed in a given species for a specific tissue or condition, evaluating differential expression, discovering variants, and evaluating allele-specific ex
Externí odkaz:
https://doaj.org/article/14dd912ea5774930b0d9c8fe41bf6326
Autor:
Stephen A Goff, Matthew eVaughn, Sheldon eMcKay, Eric eLyons, Ann E Stapleton, Damian eGessler, Naim eMatasci, Liya eWang, Matthew eHanlon, Andrew eLenards, Andy eMuir, Nirav eMerchant, Sonya eLowry, Stephen eMock, Matthew eHelmke, Adam eKubach, Martha eNarro, Nicole eHopkins, David eMicklos, Uwe eHilgert, Michael eGonzales, Chris eJordan, Edwin eSkidmore, Rion eDooley, John eCazes, Robert eMcLay, Zhenyuan eLu, Shiran ePasternak, Lars eKoesterke, William H Piel, Ruth eGrene, Christos eNoutsos, Karla eGendler, Xin eFeng, Chunlao eTang, Monica eLent, Seung-jin eKim, Kristian eKvilekval, B.S. eManjunath, Val eTannen, Alexandros eStamatakis, Michael eSanderson, Stephen M Welch, Karen eCranston, Pamela eSoltis, Douglas eSoltis, Brian eO'Meara, Cecile eAne, Tom eBrutnell, Daniel J Kleibenstein, Jeffrey W White, Jim eLeebens-Mack, Michael J Donoghue, Edgar P Spalding, Todd J Vision, Christopher R Myers, David eLowenthal, Brian J Enquist, Brad eBoyle, Ali eAkoglu, Greg eAndrews, Sudha eRam, Doreen eWare, Lincoln eStein, Dan eStanzione
Publikováno v:
Frontiers in Plant Science, Vol 2 (2011)
The iPlant Collaborative (iPlant) is a United States National Science Foundation (NSF) funded project that aims to create an innovative, comprehensive, and foundational cyberinfrastructure in support of plant biology research (PSCIC, 2006). iPlant is
Externí odkaz:
https://doaj.org/article/5e1ca1e1477b430c881127e01f2b4ef3
Publikováno v:
Viruses, Vol 15, Iss 2, p 474 (2023)
Host factor tRNAs facilitate the replication of retroviruses such as human immunodeficiency virus type 1 (HIV-1). HIV-1 uses human tRNALys3 as the primer for reverse transcription, and the assembly of HIV-1 structural protein Gag at the plasma membra
Externí odkaz:
https://doaj.org/article/b5891c381b9f4cb7a210349f98c6dc9b
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-5 (2020)
Abstract Transfection, the process of introducing purified nucleic acids into cells, and viral transduction, viral-mediated nucleic acid transfer, are two commonly utilized techniques for gene delivery in the research setting. Transfection allows pur
Externí odkaz:
https://doaj.org/article/e974ef82c36e482591496ba7f66c40de
Autor:
Shelby Winans, Stephen P Goff
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009147 (2020)
The central function of the retroviral integrase protein (IN) is to catalyze the integration of viral DNA into the host genome to form the provirus. The IN protein has also been reported to play a role in a number of other processes throughout the re
Externí odkaz:
https://doaj.org/article/683eff356c794c6d9be273fd5452deb0
Autor:
Huijuan Liu, Ping Li, Shaoyang Zhang, Jinnan Xiang, Ruichen Yang, Jiajia Liu, Md Shafiquzzaman, Soma Biswas, Zhanying Wei, Zhenlin Zhang, Xin Zhou, Feng Yin, Yangli Xie, Stephen P. Goff, Lin Chen, Baojie Li
Publikováno v:
Nature Genetics. 54:1946-1958
Specialized connective tissues, including bone and adipose tissues, control various physiological activities, including mineral and energy homeostasis. However, the identity of stem cells maintaining these tissues throughout adulthood remains elusive
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Conjugation of small ubiquitin-like modifiers (SUMOs) to substrate proteins is a posttranslational protein modification that affects a diverse range of physiological processes. Global inhibition of SUMO conjugation in mice results in embryon
Externí odkaz:
https://doaj.org/article/cce4db26578d48369ff50646e0205640
Autor:
Stephen P. Goff
Publikováno v:
Viruses, Vol 13, Iss 11, p 2248 (2021)
Retroviral infection delivers an RNA genome into the cytoplasm that serves as the template for the synthesis of a linear double-stranded DNA copy by the viral reverse transcriptase. Within the nucleus this linear DNA gives rise to extrachromosomal ci
Externí odkaz:
https://doaj.org/article/41726627a2224ac9b2b10b07daa22d79
Autor:
Oya Cingöz, Stephen P. Goff
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Effective host immune responses against viral infection rely on the detection of the virus, activation of downstream signaling pathways, and the secretion of interferons (IFNs) and other cytokines. Many viruses can potently stimulate these r
Externí odkaz:
https://doaj.org/article/f20d19c90cc44177b60f48cfb5900951
Autor:
Xuhua Tang, Yiping Zhu, Stacey L. Baker, Matthew W. Bowler, Benjamin Jieming Chen, Chen Chen, J. Robert Hogg, Stephen P. Goff, Haiwei Song
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Retroviral reverse transcriptase from Moloney Murine Leukemia Virus (MoMLV) requires interaction with peptidyl release factor 1. Here, the authors report the crystal structure of this complex, and provide insights into how MoMLV uses the host transla
Externí odkaz:
https://doaj.org/article/7f530fbe22d7490e8ba014489e46d784