Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Stephen A Buckley"'
Autor:
Michael E Habicht, Raffaella Bianucci, Stephen A Buckley, Joann Fletcher, Abigail S Bouwman, Lena M Öhrström, Roger Seiler, Francesco M Galassi, Irka Hajdas, Eleni Vassilika, Thomas Böni, Maciej Henneberg, Frank J Rühli
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166571 (2016)
Queen Nefertari, the favourite Royal Consort of Pharaoh Ramses II (Ancient Egypt, New Kingdom, 19th Dynasty c. 1250 BC) is famous for her beautifully decorated tomb in the Valley of the Queens. Her burial was plundered in ancient times yet still many
Externí odkaz:
https://doaj.org/article/8f832481dac14ae4b50124b3077602b1
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103608 (2014)
Traditional theories on ancient Egyptian mummification postulate that in the prehistoric period (i.e. the Neolithic and Chalcolithic periods, 5th and 4th millennia B.C.) bodies were naturally desiccated through the action of the hot, dry desert sand.
Externí odkaz:
https://doaj.org/article/072a3582d02a491d9638eecf6d733a2f
Autor:
Magdalena Kurtyka, Frank Wessely, Sarah Bau, Eseoghene Ifie, Liqun He, Nienke M. de Wit, Alberte Bay Villekjær Pedersen, Maximilian Keller, Caleb Webber, Helga E. de Vries, Olaf Ansorge, Christer Betsholtz, Marijke De Bock, Catarina Chaves, Birger Brodin, Morten S. Nielsen, Winfried Neuhaus, Robert D. Bell, Tamás Letoha, Axel H. Meyer, Germán Leparc, Martin Lenter, Dominique Lesuisse, Zameel M. Cader, Stephen T. Buckley, Irena Loryan, Claus U. Pietrzik
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151406- (2024)
Despite extensive research, targeted delivery of substances to the brain still poses a great challenge due to the selectivity of the blood-brain barrier (BBB). Most molecules require either carrier- or receptor-mediated transport systems to reach the
Externí odkaz:
https://doaj.org/article/24cf1f3bfe6c41b79a62e5eaa26fce38
Autor:
Burak Ozgür, Elena Puris, Andreas Brachner, Antje Appelt-Menzel, Sabrina Oerter, Viktor Balzer, Mikkel Roland Holst, Rasmus Folmann Christiansen, Kathrine Hyldig, Stephen T. Buckley, Mie Kristensen, Seppo Auriola, Allan Jensen, Gert Fricker, Morten Schallburg Nielsen, Winfried Neuhaus, Birger Brodin
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Blood-brain barrier (BBB) models based on primary murine, bovine, and porcine brain capillary endothelial cell cultures have long been regarded as robust models with appropriate properties to examine the functional transport of sm
Externí odkaz:
https://doaj.org/article/a725aae18819471b8862ddc5715b995e
Autor:
Christian T. Madsen, Jan C. Refsgaard, Felix G. Teufel, Sonny K. Kjærulff, Zhe Wang, Guangjun Meng, Carsten Jessen, Petteri Heljo, Qunfeng Jiang, Xin Zhao, Bo Wu, Xueping Zhou, Yang Tang, Jacob F. Jeppesen, Christian D. Kelstrup, Stephen T. Buckley, Søren Tullin, Jan Nygaard-Jensen, Xiaoli Chen, Fang Zhang, Jesper V. Olsen, Dan Han, Mads Grønborg, Ulrik de Lichtenberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Bioactive peptides regulate many physiological functions but progress in discovering them has been slow. Here, the authors use a machine learning framework to predict mammalian peptide candidates from the global and local structure of large-scale tis
Externí odkaz:
https://doaj.org/article/a22e4dc1d677467ea63d53214d5a93bc
Autor:
Irena Loryan, Andreas Reichel, Bo Feng, Christoffer Bundgaard, Christopher Shaffer, Cory Kalvass, Dallas Bednarczyk, Denise Morrison, Dominique Lesuisse, Edmund Hoppe, Georg C. Terstappen, Holger Fischer, Li Di, Nicola Colclough, Scott Summerfield, Stephen T. Buckley, Tristan S. Maurer, Markus Fridén
Publikováno v:
Pharmaceutical Research. 39:1321-1341
Purpose More than 15 years have passed since the first description of the unbound brain-to-plasma partition coefficient (Kp,uu,brain) by Prof. Margareta Hammarlund-Udenaes, which was enabled by advancements in experimental methodologies including cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450f3186fa63b212c77d3ed7977fbf35
https://doi.org/10.1007/s11095-022-03246-6
https://doi.org/10.1007/s11095-022-03246-6
Autor:
Andreas Vegge, Jacob Wainer, Joy Collins, Ellen Marie Straarup, Ley Mikkel Wennemoes Hvitfeld, Siddartha Tamang, Herskind Peter, Stephen T. Buckley, Rikke Kaae Kirk, Ulrik Lytt Rahbek, Keiko Ishida, Xiaoya Lu, Brian Mouridsen, Jespersen Mikkel Oliver, Mette Poulsen, Stefán B Gunnarsson, Frantisek Hubalek, Johannes Josef Fels, Jorrit Jeroen Water, Alison Hayward, Adam Bohr, Robert Langer, Giovanni Traverso, Abramson Alex G, Morten Revsgaard Frederiksen, Brian Jensen, Jesper Peter Windum, Niclas Roxhed
Publikováno v:
Nat Biotechnol
Oral administration provides a simple and non-invasive approach for drug delivery. However, due to poor absorption and swift enzymatic degradation in the gastrointestinal tract, a wide range of molecules must be parenterally injected to attain requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3bd9e6eb963ac954ee4719462cdd4e
https://doi.org/10.1038/s41587-021-01024-0
https://doi.org/10.1038/s41587-021-01024-0
Autor:
Kristina R. Rivera, Jenni Pessi, Vincent Andersson, Henning Gustafsson, Lise Lotte Gluud, Stephen T. Buckley
Publikováno v:
European Journal of Pharmaceutical Sciences. 185:106426
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1027db556bb902ff250aa4745bf024b3
https://doi.org/10.1016/j.ejps.2023.106426
https://doi.org/10.1016/j.ejps.2023.106426
Autor:
Kristina R. Rivera, Jenni Pessi, Vincent Andersson, Henning Gustafsson, Lise Lotte Gluud, Stephen T. Buckley
Publikováno v:
European Journal of Pharmaceutical Sciences. 183:106386
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3b46897f2f348be3ed64b240240fb4
https://doi.org/10.1016/j.ejps.2023.106386
https://doi.org/10.1016/j.ejps.2023.106386
Autor:
Aohua Wang, Yue Wu, Stephen T. Buckley, Mingshi Yang, Yong Gan, Weiwei Fan, Lars Hovgaard, Jorrit Jeroen Water
Publikováno v:
Journal of Pharmaceutical Sciences. 108:2128-2135
Absorption enhancers are often a major component of solid oral peptide formulations as compared to the active pharmaceutical ingredient and excipients. This commonly results in poor tabletability that is hard to mitigate in direct compaction by addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6869332d58b2a19399007da267ead5
https://doi.org/10.1016/j.xphs.2019.01.025
https://doi.org/10.1016/j.xphs.2019.01.025