Zobrazeno 1 - 10
of 528
pro vyhledávání: '"Stephen A Black"'
Autor:
Maria J. Santiago, Srinivasan Chinnapaiyan, Kingshuk Panda, Md. Sohanur Rahman, Suvankar Ghorai, Joseph H. Lucas, Stephen M. Black, Irfan Rahman, Hoshang J. Unwalla
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Transforming Growth Factor Beta1 (TGF-β1) signaling is upregulated in Chronic Obstructive Pulmonary disease (COPD), smokers, and people living with HIV. Cigarette smoking and HIV are also independent risk factors for COPD. Chronic inflammat
Externí odkaz:
https://doaj.org/article/8235dbd4a8fe4dfc95490a03b9d3dd0e
Autor:
Anlin Feng, Yesenia Moreno Caro, Colin Gardner, Garrett Grischo, Ying Liang, Praveen D. Wickremasinghe, Michaela Polmann, Mrinalini Kala, Timothy Marlowe, Stephen M. Black, Kenneth S. Knox, Ting Wang
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with a poor prognosis. Current/available clinical prediction tools have limited sensitivity and accuracy when evaluating clinical outcomes of IPF. Research has shown
Externí odkaz:
https://doaj.org/article/1671331977914ca4954a1cf8a6886a76
Autor:
Marissa D. Pokharel, Alejandro Garcia-Flores, David Marciano, Maria C. Franco, Jeffrey R. Fineman, Saurabh Aggarwal, Ting Wang, Stephen M. Black
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103049- (2024)
Once thought of in terms of bioenergetics, mitochondria are now widely accepted as both the orchestrator of cellular health and the gatekeeper of cell death. The pulmonary disease field has performed extensive efforts to explore the role of mitochond
Externí odkaz:
https://doaj.org/article/ca0f8236e2604227a1b3d514218b84a6
Autor:
Maria J. Santiago, Srinivasan Chinnapaiyan, Kingshuk Panda, Md. Sohanur Rahman, Suvankar Ghorai, Irfan Rahman, Stephen M. Black, Yuan Liu, Hoshang J. Unwalla
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8809 (2024)
microRNAs have emerged as essential regulators of health and disease, attracting significant attention from researchers across diverse disciplines. Following their identification as noncoding oligonucleotides intricately involved in post-transcriptio
Externí odkaz:
https://doaj.org/article/488e88b0547f4f40b5ff06c01755af25
Autor:
Shuxin Liang, Changlei Bao, Zi Yang, Shiyun Liu, Yanan Sun, Weitao Cao, Ting Wang, Tae-Hwi Schwantes-An, John S. Choy, Samisubbu Naidu, Ang Luo, Wenguang Yin, Stephen M. Black, Jian Wang, Pixin Ran, Ankit A. Desai, Haiyang Tang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Cardiopulmonary complications are major drivers of mortality caused by the SARS-CoV-2 virus. Interleukin-18, an inflammasome-induced cytokine, has emerged as a novel mediator of cardiopulmonary pathologies but its regulation via SARS-CoV-2 s
Externí odkaz:
https://doaj.org/article/d445e26603ba40349d02e11cee010aa0
Autor:
Anlin Feng, Marissa D. Pokharel, Ying Liang, Wenli Ma, Saurabh Aggarwal, Stephen M. Black, Ting Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4574 (2024)
Sepsis continues to overwhelm hospital systems with its high mortality rate and prevalence. A strategy to reduce the strain of sepsis on hospital systems is to develop a diagnostic/prognostic measure that identifies patients who are more susceptible
Externí odkaz:
https://doaj.org/article/dac5af8353f048649a42c1efa5521945
Autor:
Marissa D. Pokharel, David P. Marciano, Panfeng Fu, Maria Clara Franco, Hoshang Unwalla, Kim Tieu, Jeffrey R. Fineman, Ting Wang, Stephen M. Black
Publikováno v:
Redox Biology, Vol 64, Iss , Pp 102797- (2023)
Mitochondria are highly dynamic organelles essential for cell metabolism, growth, and function. It is becoming increasingly clear that endothelial cell dysfunction significantly contributes to the pathogenesis and vascular remodeling of various lung
Externí odkaz:
https://doaj.org/article/5481895c4f834230aa1ddd24f67cf8a7
Autor:
Manivannan Yegambaram, Xutong Sun, Alejandro Garcia Flores, Qing Lu, Jamie Soto, Jaime Richards, Saurabh Aggarwal, Ting Wang, Haiwei Gu, Jeffrey R. Fineman, Stephen M. Black
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17533 (2023)
The disruption of mitochondrial dynamics has been identified in cardiovascular diseases, including pulmonary hypertension (PH), ischemia-reperfusion injury, heart failure, and cardiomyopathy. Mitofusin 2 (Mfn2) is abundantly expressed in heart and pu
Externí odkaz:
https://doaj.org/article/8d0df2ead0b24ccc867259c09b21339f
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract N6‐methyladenosine (m6A) is the most common methylation modification in mammalian messenger RNA (mRNA) and noncoding RNAs. m6A modification plays a role in the regulation of gene expression and deregulation of m6A methylation has been impl
Externí odkaz:
https://doaj.org/article/f13ee4fd670d4e47b4aec76eee07099e
Autor:
Jialin Wu, Ying Liang, Panfeng Fu, Anlin Feng, Qing Lu, Hoshang J. Unwalla, David P. Marciano, Stephen M. Black, Ting Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16083 (2023)
Mechanical ventilation (MV) is a life-supporting strategy employed in the Intensive Care Unit (ICU). However, MV-associated mechanical stress exacerbates existing lung inflammation in ICU patients, resulting in limited improvement in mortality and a
Externí odkaz:
https://doaj.org/article/a7707f9e3efa439cb3b6cc407ceeb02f