Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Stephen A, Vella"'
Autor:
Zhu-Hong Li, Thayer P. King, Lawrence Ayong, Beejan Asady, Xinjiang Cai, Taufiq Rahman, Stephen A. Vella, Isabelle Coppens, Sandip Patel, Silvia N. J. Moreno
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Two-pore channels (TPCs) are cation channels that localize to acidic organelles to regulate Ca2+ dependent events. Here, Li et al. characterize a TPC from Toxoplasma gondii(TgTPC) that localizes to the apicoplast, is critical for maintaining its inte
Externí odkaz:
https://doaj.org/article/40af680df6674080819ee06c0c3a8c98
Autor:
Luis Peñarrubia, Maria Ruiz, Roberto Porco, Sonia N. Rao, Stephen A. Vella, Martí Juanola-Falgarona, Davide Manissero, Marta López-Fontanals, Josep Pareja
Publikováno v:
International Journal of Infectious Diseases, Vol 105, Iss , Pp 241-242 (2021)
Externí odkaz:
https://doaj.org/article/65320571787c46368877f342610068df
Autor:
Andrew J. Stasic, Nathan M. Chasen, Eric J. Dykes, Stephen A. Vella, Beejan Asady, Vincent J. Starai, Silvia N.J. Moreno
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2132-2146.e7 (2019)
Summary: Vacuolar-proton ATPases (V-ATPases) are conserved complexes that couple the hydrolysis of ATP to the pumping of protons across membranes. V-ATPases are known to play diverse roles in cellular physiology. We studied the Toxoplasma gondii V-AT
Externí odkaz:
https://doaj.org/article/b5f77327b6c845ab8d111eae24734201
Autor:
Ciro D. Cordeiro, Mojtaba Sedigh Fazli, Silvia N.J. Moreno, Shannon Quinn, Stephen A. Vella, Eric J. Dykes, Andrew J. Stasic, Roberto Docampo
Publikováno v:
Molecular Microbiology. 115:1054-1068
Ca2+ is a universal intracellular signal that regulates many cellular functions. In Toxoplasma gondii, the controlled influx of extracellular and intracellular Ca2+ into the cytosol initiates a signaling cascade that promotes pathogenic processes lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eabbd42a97d69ea6443ed6a9599644db
https://doi.org/10.1111/mmi.14722
https://doi.org/10.1111/mmi.14722
Autor:
Stephen A. Vella, Lawrence Ayong, Isabelle Coppens, Silvia N. J. Moreno, Xinjiang Cai, Thayer P. King, Beejan Asady, Taufiq Rahman, Zhu Hong Li, Sandip Patel
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Funder: U.S. Department of Health & Human Services | National Institutes of Health (NIH)
Funder: U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
Two-pore channels (TPCs) are a
Funder: U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
Two-pore channels (TPCs) are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f82e76fe7c08d541f46cdb6b1a1664
https://www.repository.cam.ac.uk/handle/1810/330398
https://www.repository.cam.ac.uk/handle/1810/330398
Autor:
Andrew J, Stasic, Eric J, Dykes, Ciro D, Cordeiro, Stephen A, Vella, Mojtaba S, Fazli, Shannon, Quinn, Roberto, Docampo, Silvia N J, Moreno
Publikováno v:
Mol Microbiol
Ca(2+) is a universal intracellular signal that regulates many cellular functions. In Toxoplasma gondii, the controlled influx of extracellular and intracellular Ca(2+) into the cytosol initiates a signaling cascade that promotes pathogenic processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75706161c8dc625a7f5a6745e62b8cce
https://pubmed.ncbi.nlm.nih.gov/33793004
https://pubmed.ncbi.nlm.nih.gov/33793004
Autor:
Phillip Dean, James A. Wohlschlegel, Silvia N.J. Moreno, Faris Almutairi, Menbere Wendimu, Mohammed Alqinyah, Shima Rayatpisheh, Roseanne Davila-Rivera, Stephen A. Vella, Shelley B. Hooks
Publikováno v:
Cell Signal
Chronic activation of microglia is a driving factor in the progression of neuroinflammatory diseases, and mechanisms that regulate microglial inflammatory signaling are potential targets for novel therapeutics. Regulator of G protein Signaling 10 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e1d5e2cc3764a6e709b9ff1aa2e9fb
https://pubmed.ncbi.nlm.nih.gov/33705894
https://pubmed.ncbi.nlm.nih.gov/33705894
Autor:
Miryam Andrea Hortua Triana, Stephen A. Vella, Christina A. Moore, Evgeniy Potapenko, Zhu-Hong Li, Silvia N.J. Moreno
Toxoplasma gondii , an obligate intracellular parasite, is capable of invading virtually any nucleated cell. Active invasion by the parasite is a precise process and intracellular parasites reside and replicate inside a parasitophorous vacuole (PV).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd9e7a11fec0001530db46e5355e118e
https://doi.org/10.1101/2020.03.06.980508
https://doi.org/10.1101/2020.03.06.980508
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1865:1846-1856
Toxoplasma gondii has a complex life cycle involving different hosts and is dependent on fast responses, as the parasite reacts to changing environmental conditions. T. gondii causes disease by lysing the host cells that it infects and it does this b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177d05f1ef966c16e908dcbd0cecf7e3
https://doi.org/10.1016/j.bbamcr.2018.08.004
https://doi.org/10.1016/j.bbamcr.2018.08.004
Autor:
Maria Ruiz, Josep Pareja, Marta López-Fontanals, Martí Juanola-Falgarona, Luis Peñarrubia, Sonia N. Rao, Stephen A Vella, Davide Manissero, Roberto Porco
Publikováno v:
International Journal of Infectious Diseases
International Journal of Infectious Diseases, Vol 105, Iss, Pp 241-242 (2021)
International Journal of Infectious Diseases, Vol 105, Iss, Pp 241-242 (2021)
In this study, five SARS-CoV-2 PCR assay panels were evaluated against the accumulated genetic variability of the virus to assess the effect on sensitivity of the individual assays.As of week 21, 2020, the complete set of available SARS-CoV-2 genomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0a9867960587b4c3d88ec824369d06
https://doi.org/10.1016/j.ijid.2021.01.049
https://doi.org/10.1016/j.ijid.2021.01.049