Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Stephen A, Lesko"'
Autor:
David A. Van Echo, Nancy Tait, Ming Tan, Stephen A. Lesko, Faye Feldman, Paul O. P. Ts'o, Olga Goloubeva, Katherine Tkaczuk, Zhao-Ping Lum
Publikováno v:
Breast Cancer Research and Treatment. 111:355-364
Purpose: A negative selection method for the enumeration and characterization of circulating epithelial/cancer cells (CCC) in Breast Cancer (BC) patients is described. This manual procedure yields reproducible results of high sensitivity and selectiv
Autor:
G. Steven Bova, Alan W. Partin, Jürgen Pannek, Paul O. P. Ts'o, Zheng Pin Wang, Stephen A. Lesko
Publikováno v:
Urology. 49:881-885
Objectives. To develop a procedure to be used to find, identify, and characterize the living prostate cancer cells in the blood of patients with prostate cancer. Methods. The procedure is based on a negative selection approach that removes most of th
Publikováno v:
Cancer Chemotherapy and Pharmacology. 40:101-111
The rate of reaction of monochlorobimane with glutathione (GSH) was measured in native human mammary MCF-7 adenocarcinoma cells (MCF-7wt) and sublines displaying resistance to 4-hydroperoxycyclophosphamide (MCF-7hc) and adriamycin (MCF-7adr) prior to
Autor:
Katherine H Rak, Tkaczuk, Nancy S, Tait, Olga, Ioffe, Ming, Tan, Olga G, Goloubeva, Stephen A, Lesko, Scott F, Deamond, Daobiao, Zhou, Zheng P, Lum, Michael J, Sutula, David, Van Echo, Paul O P, Ts'o
Publikováno v:
Discovery medicine. 12(62)
Chemotherapy is frequently used in the treatment of advanced breast cancer. The identification of patient-specific tumor characteristics that can improve the ability to predict response to chemotherapy would help optimize advanced breast cancer treat
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 26:41-44
A rapid, quantitative in situ mRNA hybridization method was developed to study human β1-interferon gene expression through the application of biotinylated DNA probes and computer-assisted microscopy. The β1-interferon DNA probe was chemically bioti
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 26:35-40
This paper describes a rapid, nonradioactive in situ mRNA hybridization method through the use of a chemically biotinylated DNA probe for the detection of human β1-IFN mRNA. The chemically biotinylated DNA probe is characterized with respects to: (1
Publikováno v:
Experimental cell research. 219(2)
The simultaneous 3D arrangement of the interphase centromeres of chromosomes 7, 11, and 17 in unstimulated human T-lymphocytes is analyzed. Using triple in situ hybridization in combination with optical sectioning and image processing, the identifica
Autor:
Stephen A. Lesko, M. Tan, S. Deamond, Olga B. Ioffe, D. A. Vanecho, Saranya Chumsri, Nancy Tait, Paul O. P. Ts'o, K. Tkaczuk, M. Mohiuddin, M. J. Sutula
Publikováno v:
Journal of Clinical Oncology. 27:1119-1119
1119 Background: There are limited options for selecting an optimal treatment regimen for ABC patients (pts). DRIT is a platform technology that provides a profile of a patient's tumor's sensitivity or resistance to commonly used chemotherapeutic, ho
Autor:
Naimish Pandya, M. Tan, Stephen A. Lesko, Nancy Tait, Katherine R. Tkaczuk, D. A. Van Echo, M. J. Sutula, S. Deamond, Paul O. P. Ts'o, Olga B. Ioffe
Publikováno v:
Journal of Clinical Oncology. 27:e15079-e15079
e15079 Background: There are currently limited options for selecting an optimal treatment regimen for AGC patients. The Drug Response Indicator Test (DRIT) is a platform technology that provides a detailed profile of a patient's tumor response to com
Autor:
W Rogers, Paul O. P. Ts'o, D. A. Vanecho, KR Tkaczuk, Nancy Tait, Ming Tan, E Shan, Olga B. Ioffe, SF Deamond, Stephen A. Lesko, JR Daniel, Lum Zp
Publikováno v:
Cancer Research. 69:6075
Abstract #6075 We conducted a retrospective study of DRIT, an investigational diagnostic test to predict chemotherapy and endocrine therapy treatment outcomes in ABC. DRIT is a quantitative measurement of Drug Response Indicator (DRI) expression leve