Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Stephen A, Hopkins"'
Autor:
Margaret E. Hoadley, James Galea, Navneet Singh, Sharon Hulme, David O. Ajao, Nancy Rothwell, Andrew King, Pippa Tyrrell, Stephen J. Hopkins
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-12 (2023)
Abstract Background We sought to determine the extent to which cortisol suppressed innate and T cell-mediated cytokine production and whether it could be involved in reducing peripheral cytokine production following subarachnoid haemorrhage (SAH). Me
Externí odkaz:
https://doaj.org/article/662161bb7a9b41a3a4fbca781712922f
Autor:
W. Lee McVey, Stephen R. Hopkins
Publikováno v:
IEEE Solid-State Circuits Magazine. 11:28-31
Two of Larry Nagel's friends from his junior and high school days, Steve Hopkins and Lee McVey, share their memories of his early days in ham radio.
Publikováno v:
Accounts of Chemical Research. 51:2169-2178
Acoustic cavitation (the growth, oscillation, and rapid collapse of bubbles in a liquid) occurs in all liquids irradiated with sufficient intensity of sound or ultrasound. The collapse of such bubbles creates local heating and provides a unique sourc
Autor:
Nancy J. Rothwell, Calvin Heal, Craig J. Smith, Stephen J. Hopkins, Karen Hopkins, Andy Vail, Pippa J. Tyrrell, Adrian R Parry-Jones, Stuart M. Allan, Sylvia Scarth, Sharon Hulme, Margaret E. Hoadley
Publikováno v:
Smith, C J, Hulme, S, Vail, A, Heal, C, Parry-Jones, A R, Scarth, S, Hopkins, K, Hoadley, M, Allan, S M, Rothwell, N J, Hopkins, S J & Tyrrell, P J 2018, ' SCIL-STROKE (Subcutaneous Interleukin-1 Receptor Antagonist in Ischemic Stroke) : A Randomized Controlled Phase 2 Trial ', Stroke, vol. 49, no. 5, pp. 1210-1216 . https://doi.org/10.1161/STROKEAHA.118.020750
Background and Purpose— The proinflammatory cytokine IL-1 (interleukin-1) has a deleterious role in cerebral ischemia, which is attenuated by IL-1 receptor antagonist (IL-1Ra). IL-1 induces peripheral inflammatory mediators, such as interleukin-6,
Autor:
Nancy J. Rothwell, Stephen J. Hopkins, Sharon Hulme, Kayode Ogungbenro, Pippa J. Tyrrell, James Galea
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 43:1-12
Interleukin-1 receptor antagonist, a naturally-occurring antagonist to the pro-inflammatory cytokine Interleukin-1, is already in clinical use. In experimental models of stroke, Interleukin-1 receptor antagonist in cerebrospinal fluid has been associ
Autor:
Pippa J. Tyrrell, Mark Woodhead, Diederik van de Beek, Stephen J. Hopkins, Mario Di Napoli, Lalit Kalra, Javier Garau, Craig J. Smith, Amit Kishore, Joan Montaner, Andy Vail, Anthony Rudd, Peter Langhorne, Christine Roffe, Andreas Meisel, Ángel Chamorro
Publikováno v:
Stroke; a journal of cerebral circulation. 46(5):1202-1209
Background and Purpose— Diagnosis of pneumonia complicating stroke is challenging, and there are currently no consensus diagnostic criteria. As a first step in developing such consensus-based diagnostic criteria, we undertook a systematic review to
Autor:
Rainer Hinz, G. Holland, Zhangjie Su, Alexander Gerhard, H.J.A. Hunter, Cem Griffiths, Stephen J. Hopkins, Peter S. Talbot, C.E. Kleyn
Publikováno v:
British Journal of Dermatology. 175:1082-1084
Psoriasis is a chronic, immune-mediated inflammatory skin disease affecting approximately 2% of the population.1 It is associated with multiple comorbidities including arthritis, cardiovascular disease and the metabolic syndrome and as such is widely
Autor:
Sharon Hulme, Andy Vail, Hiren C. Patel, Karen J. Illingworth, Nikolaos Tzerakis, Kayode Ogungbenro, James Galea, Andrew T. King, Pippa J. Tyrrell, Stephen J. Hopkins, Margaret E. Hoadley, Catherine McMahon, Sylvia Scarth, Nancy J. Rothwell
Publikováno v:
Galea, J, Ogungbenro, K, Hulme, S, Patel, H, Scarth, S, Hoadley, M, Illingworth, K, McMahon, C J, Tzerakis, N, King, A T, Vail, A, Hopkins, S J, Rothwell, N & Tyrrell, P 2017, ' Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage : results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study ', Journal of neurosurgery, vol. 128, no. 2, pp. 515-523 . https://doi.org/10.3171/2016.9.JNS16615
OBJECTIVEAneurysmal subarachnoid hemorrhage (aSAH) is a devastating cerebrovascular event with long-term morbidity and mortality. Patients who survive the initial bleeding are likely to suffer further early brain injury arising from a plethora of pat
Publikováno v:
Physiological Measurement. 35:N21-N28
Microdialysis of macromolecules within the brain provides a unique insight into physiological and pathological processes occurring within an otherwise inaccessible cranial cavity. The physically restricted nature of the intracranial compartment may p
Publikováno v:
Journal of Immunological Methods. 396:157-162
Failure to match assay matrices with samples in immunoassays can result in incorrect sample values being reported. For multiplex assays this presents particular problems, due to the need to find a matrix suitable for all the analytes. Here, we descri