Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephen A, Hare"'
Publikováno v:
Microbial Cell, Vol 9, Iss 4, Pp 84-102 (2022)
Not all treasure is silver and gold; for pathogenic bacteria, iron is the most precious and the most pillaged of metallic elements. Iron is essential for the survival and growth of all life; however free iron is scarce for bacteria inside human hosts
Externí odkaz:
https://doaj.org/article/3daf4531e78049b8a1f413c7261c3306
Autor:
Julian A. Rycroft, Bridget Gollan, Grzegorz J. Grabe, Alexander Hall, Angela M. Cheverton, Gerald Larrouy-Maumus, Stephen A. Hare, Sophie Helaine
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The recalcitrance of many infections to antibiotic treatment may be due to the presence of ‘persisters’, or non-growing, antibiotic-tolerant bacteria. Here, the authors study the structures and functions of aminoacyl-tRNA acetyltransferase toxins
Externí odkaz:
https://doaj.org/article/3bed1ef83f1d4e429b13f75bbb4a9545
Autor:
Laurent Dubois, Sophie Helaine, Stephen A Hare, Alexander M J Hall, Rhodri M. L. Morgan, Tyler A Sisley, Rachel T. Giorgio, Grzegorz J Grabe, Julian A Rycroft
Publikováno v:
Nature Chemical Biology. 17:1296-1304
Toxin-antitoxin (TA) systems are a large family of genes implicated in the regulation of bacterial growth and its arrest in response to attacks. These systems encode nonsecreted toxins and antitoxins that specifically pair, even when present in sever
Publikováno v:
Microbial cell (Graz, Austria). 9(4)
Not all treasure is silver and gold; for pathogenic bacteria, iron is the most precious and the most pillaged of metallic elements. Iron is essential for the survival and growth of all life; however free iron is scarce for bacteria inside human hosts
Autor:
Stephen A, Hare
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1865(4)
The critical need for iron presents a challenge for pathogenic bacteria that must survive in an environment bereft of accessible iron due to a natural low bioavailability and their host's nutritional immunity. Appropriating haem, either direct from h
Autor:
Angela M, Cheverton, Bridget, Gollan, Michal, Przydacz, Chi T, Wong, Anastasia, Mylona, Stephen A, Hare, Sophie, Helaine
Publikováno v:
Molecular cell. 63(1)
The recalcitrance of many bacterial infections to antibiotic treatment is thought to be due to the presence of persisters that are non-growing, antibiotic-insensitive cells. Eventually, persisters resume growth, accounting for relapses of infection.