Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Stephen, Spellman"'
Autor:
Jing Dong, Shahram Arsang-Jang, Tao Zhang, Zhongyuan Chen, Yung-Tsi Bolon, Stephen Spellman, Raul Urrutia, Paul Auer, Wael Saber
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract Mitochondrial DNA (mtDNA) variants in patients with myelodysplastic neoplasms (MDS) are shown to be prognostic of outcomes after allogeneic hematopoietic cell transplantation (allo-HCT). However, the prognostic impact of donor mtDNA variants
Externí odkaz:
https://doaj.org/article/a115d334e5ad453fb607ef4a9bba13e5
Autor:
Guru Subramanian Guru Murthy, Tao Zhang, Yung-Tsi Bolon, Stephen Spellman, Jing Dong, Paul Auer, Wael Saber
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-4 (2024)
Abstract Disease relapse remains a major barrier to success after allogeneic hematopoietic cell transplantation (allo-HCT) in myelodysplastic neoplasms (MDS). While certain high risk genomic alterations are associated with increased risk of relapse,
Externí odkaz:
https://doaj.org/article/4237d40728e34d7aa04b78365928ddf2
Autor:
Tao Zhang, Paul Auer, Jing Dong, Corey Cutler, Amy E. Dezern, Shahinaz M. Gadalla, H. Joachim Deeg, Aziz Nazha, Karen-Sue Carlson, Stephen Spellman, Yung-Tsi Bolon, Wael Saber
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Recurrent mutations in TP53, RAS pathway and JAK2 genes were shown to be highly prognostic of allogeneic hematopoietic cell transplant (alloHCT) outcomes in myelodysplastic syndromes (MDS). However, a significant proportion of MDS patients h
Externí odkaz:
https://doaj.org/article/070e43d5f7fa42d6b57cf3d32d7704b7
Autor:
Jing Dong, Christopher Staffi Buradagunta, Tao Zhang, Stephen Spellman, Yung-Tsi Bolon, Amy E. DeZern, Shahinaz M. Gadalla, H. Joachim Deeg, Aziz Nazha, Corey Cutler, Chao Cheng, Raul Urrutia, Paul Auer, Wael Saber
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Despite mitochondrial DNA (mtDNA) mutations are common events in cancer, their global frequency and clinical impact have not been comprehensively characterized in patients with myelodysplastic neoplasia (also known as myelodysplastic syndrom
Externí odkaz:
https://doaj.org/article/895c2192249f43b6861d6c677d997fa6
Autor:
Johannes Schetelig, Henning Baldauf, Linda Koster, Michelle Kuxhausen, Falk Heidenreich, Liesbeth C. de Wreede, Stephen Spellman, Michel van Gelder, Benedetto Bruno, Francesco Onida, Vinzenz Lange, Carolin Massalski, Victoria Potter, Per Ljungman, Nicolaas Schaap, Patrick Hayden, Stephanie J. Lee, Nicolaus Kröger, Kathy Hsu, Alexander H. Schmidt, Ibrahim Yakoub-Agha, Marie Robin
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/98cab44b6dfb4751a6cc5d0063c00727
Autor:
Junke Wang, Alyssa I. Clay-Gilmour, Ezgi Karaesmen, Abbas Rizvi, Qianqian Zhu, Li Yan, Leah Preus, Song Liu, Yiwen Wang, Elizabeth Griffiths, Daniel O. Stram, Loreall Pooler, Xin Sheng, Christopher Haiman, David Van Den Berg, Amy Webb, Guy Brock, Stephen Spellman, Marcelo Pasquini, Philip McCarthy, James Allan, Friedrich Stölzel, Kenan Onel, Theresa Hahn, Lara E. Sucheston-Campbell
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The role of common genetic variation in susceptibility to acute myeloid leukemia (AML), and myelodysplastic syndrome (MDS), a group of rare clonal hematologic disorders characterized by dysplastic hematopoiesis and high mortality, remains unclear. We
Externí odkaz:
https://doaj.org/article/fa262d77b31b4da591c8a81a451b985b
Autor:
Johannes Schetelig, Henning Baldauf, Linda Koster, Michelle Kuxhausen, Falk Heidenreich, Liesbeth C. de Wreede, Stephen Spellman, Michel van Gelder, Benedetto Bruno, Francesco Onida, Vinzenz Lange, Carolin Massalski, Victoria Potter, Per Ljungman, Nicolaas Schaap, Patrick Hayden, Stephanie J. Lee, Nicolaus Kröger, Kathy Hsu, Alexander H. Schmidt, Ibrahim Yakoub-Agha, Marie Robin
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Results from registry studies suggest that harnessing Natural Killer (NK) cell reactivity mediated through Killer cell Immunoglobulin-like Receptors (KIR) could reduce the risk of relapse after allogeneic Hematopoietic Cell Transplantation (HCT). Sev
Externí odkaz:
https://doaj.org/article/693c028224f942ae8e114564d060c6a0
Autor:
Simone Feurstein, Amy M. Trottier, Noel Estrada-Merly, Matthew Pozsgai, Kelsey McNeely, Michael W. Drazer, Brian Ruhle, Katharine Sadera, Ashwin L. Koppayi, Bart L. Scott, Betul Oran, Taiga Nishihori, Vaibhav Agrawal, Ayman Saad, R. Coleman Lindsley, Ryotaro Nakamura, Soyoung Kim, Zhenhuan Hu, Ronald Sobecks, Stephen Spellman, Wael Saber, Lucy A. Godley
Publikováno v:
Blood. 140:2533-2548
The frequency of pathogenic/likely pathogenic (P/LP) germ line variants in patients with myelodysplastic syndrome (MDS) diagnosed at age 40 years or less is 15% to 20%. However, there are no comprehensive studies assessing the frequency of such varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57f06b7ec8a79a8ae6c5e4a3fdadf65
https://doi.org/10.1182/blood.2022015790
https://doi.org/10.1182/blood.2022015790
Autor:
Alyssa I. Clay-Gilmour, Theresa Hahn, Leah M. Preus, Kenan Onel, Andrew Skol, Eric Hungate, Qianqian Zhu, Christopher A. Haiman, Daniel O. Stram, Loreall Pooler, Xin Sheng, Li Yan, Qian Liu, Qiang Hu, Song Liu, Sebastiano Battaglia, Xiaochun Zhu, AnneMarie W. Block, Sheila N.J. Sait, Ezgi Karaesmen, Abbas Rizvi, Daniel J. Weisdorf, Christine B. Ambrosone, David Tritchler, Eva Ellinghaus, David Ellinghaus, Martin Stanulla, Jacqueline Clavel, Laurent Orsi, Stephen Spellman, Marcelo C. Pasquini, Philip L. McCarthy, Lara E. Sucheston-Campbell
Publikováno v:
Blood Advances, Vol 1, Iss 20, Pp 1717-1728 (2017)
Abstract: The incidence and mortality rates of B-cell acute lymphoblastic leukemia (B-ALL) differ by age and sex. To determine if inherited genetic susceptibility contributes to these differences we performed 2 genome-wide association studies (GWAS)
Externí odkaz:
https://doaj.org/article/0de20af71b0145c2ae5ba542c99c7d9f
Autor:
Rupa Narayan, Abhishek Niroula, Tao Wang, Michelle Kuxhausen, Meilun He, Everett Meyer, Yi-Bin Chen, Vijaya Raj Bhatt, Amer Beitinjaneh, Taiga Nishihori, Akshay Sharma, Valerie I. Brown, Malek Kamoun, Miguel A. Diaz, Muhammad Bilal Abid, Medhat Askar, Christopher G. Kanakry, Loren Gragert, Yung-Tsi Bolon, Steven G.E. Marsh, Shahinaz M. Gadalla, Sophie Paczesny, Stephen Spellman, Stephanie J. Lee
Publikováno v:
Transplantation and Cellular Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f1c7f560c7bde4e3ce1d6ba6d2e1aed
https://doi.org/10.1016/j.jtct.2023.03.027
https://doi.org/10.1016/j.jtct.2023.03.027