Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen, Searles"'
Autor:
Valentina Ferrari, Alison Tarke, Hannah Fields, Tiffany N. Tanaka, Stephen Searles, Maurizio Zanetti
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The PD-1:PD-L1 axis is a binary interaction that delivers inhibitory signals to T cells, impeding both immune surveillance and response to immunotherapy. Here we analyzed a phenomenon whereby tumor-specific T cells induce PD-L1 upregulation in autolo
Externí odkaz:
https://doaj.org/article/e332476630c5488a88d3d7e592e6ceb5
Autor:
Jack Bui, Stephen Searles, Jarrod Yee, Preston Lee, Christine Caron, Calvin Lee, Irina Matei, David Lyden
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
Cellular and Molecular Life Sciences. 75:225-240
The purpose of this review is to explore immune-mediated mechanisms of stress surveillance in cancer, with particular emphasis on the idea that all cancers have classical hallmarks (Hanahan and Weinberg in Cell 100:57-70, 67; Cell 144:646-674, 68) th
Publikováno v:
The Journal of Immunology. 200:56.24-56.24
Cell-cell fusion is a common biological phenomenon involved in both healthy and disease conditions. Fusion occurs when two or more cells combine their plasma membranes and become a single hybrid cell that retains certain genetic information from each
Publikováno v:
The Journal of Immunology. 198:76.24-76.24
Exosomes mediate intercellular communication and regulation in many processes, including cancer-immune cell interactions. Exosomes are small (~100 nm) membrane vesicles that arise from the late endosomal pathway and contain bioactive molecules that a
Autor:
Meier, Angela, Gross, Emilie T. E., Schilling, Jan M., Seelige, Ruth, Yujin Jung, Endi Santosa, Stephen Searles, Tuo Lin, Tu, Xin M., Patel, Hemal H., Bui, Jack D.
Publikováno v:
Anesthesia & Analgesia; Jun2018, Vol. 126 Issue 6, p1910-1913, 4p
Publikováno v:
The Journal of Immunology. 188:70.8-70.8
Pneumocystis (PC) infection can range from asymptomatic colonization to fatal pneumonia in severely immunocompromised individuals. Type-I-IFNs are critical regulators of immune responses to PC. In mice lacking type-I-IFN signaling (IFNAR-/-), PC clea
Autor:
Daniel, Petras, Louis-Félix, Nothias, Robert A, Quinn, Theodore, Alexandrov, Nuno, Bandeira, Amina, Bouslimani, Gabriel, Castro-Falcón, Liangyu, Chen, Tam, Dang, Dimitrios J, Floros, Vivian, Hook, Neha, Garg, Nicole, Hoffner, Yike, Jiang, Clifford A, Kapono, Irina, Koester, Rob, Knight, Christopher A, Leber, Tie-Jun, Ling, Tal, Luzzatto-Knaan, Laura-Isobel, McCall, Aaron P, McGrath, Michael J, Meehan, Jonathan K, Merritt, Robert H, Mills, Jamie, Morton, Sonia, Podvin, Ivan, Protsyuk, Trevor, Purdy, Kendall, Satterfield, Stephen, Searles, Sahil, Shah, Sarah, Shires, Dana, Steffen, Margot, White, Jelena, Todoric, Robert, Tuttle, Aneta, Wojnicz, Valerie, Sapp, Fernando, Vargas, Jin, Yang, Chao, Zhang, Pieter C, Dorrestein
Publikováno v:
Analytical chemistry, vol 88, iss 22
Analytical Chemistry
Analytical Chemistry
The cars we drive, the homes we live in, the restaurants we visit, and the labs and offices we work in are all a part of the modern human habitat. Remarkably, little is known about the chemistry of such environments and how our own chemistries influe