Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephen, Riffle"'
Autor:
Guillaume Butler-Laporte, Gundula Povysil, Jack A Kosmicki, Elizabeth T Cirulli, Theodore Drivas, Simone Furini, Chadi Saad, Axel Schmidt, Pawel Olszewski, Urszula Korotko, Mathieu Quinodoz, Elifnaz Çelik, Kousik Kundu, Klaudia Walter, Junghyun Jung, Amy D Stockwell, Laura G Sloofman, Daniel M Jordan, Ryan C Thompson, Diane Del Valle, Nicole Simons, Esther Cheng, Robert Sebra, Eric E Schadt, Seunghee Kim-Schulze, Sacha Gnjatic, Miriam Merad, Joseph D Buxbaum, Noam D Beckmann, Alexander W Charney, Bartlomiej Przychodzen, Timothy Chang, Tess D Pottinger, Ning Shang, Fabian Brand, Francesca Fava, Francesca Mari, Karolina Chwialkowska, Magdalena Niemira, Szymon Pula, J Kenneth Baillie, Alex Stuckey, Antonio Salas, Xabier Bello, Jacobo Pardo-Seco, Alberto Gómez-Carballa, Irene Rivero-Calle, Federico Martinón-Torres, Andrea Ganna, Konrad J Karczewski, Kumar Veerapen, Mathieu Bourgey, Guillaume Bourque, Robert Jm Eveleigh, Vincenzo Forgetta, David Morrison, David Langlais, Mark Lathrop, Vincent Mooser, Tomoko Nakanishi, Robert Frithiof, Michael Hultström, Miklos Lipcsey, Yanara Marincevic-Zuniga, Jessica Nordlund, Kelly M Schiabor Barrett, William Lee, Alexandre Bolze, Simon White, Stephen Riffle, Francisco Tanudjaja, Efren Sandoval, Iva Neveux, Shaun Dabe, Nicolas Casadei, Susanne Motameny, Manal Alaamery, Salam Massadeh, Nora Aljawini, Mansour S Almutairi, Yaseen M Arabi, Saleh A Alqahtani, Fawz S Al Harthi, Amal Almutairi, Fatima Alqubaishi, Sarah Alotaibi, Albandari Binowayn, Ebtehal A Alsolm, Hadeel El Bardisy, Mohammad Fawzy, Fang Cai, Nicole Soranzo, Adam Butterworth, COVID-19 Host Genetics Initiative, DeCOI Host Genetics Group, GEN-COVID Multicenter Study (Italy), Mount Sinai Clinical Intelligence Center, GEN-COVID consortium (Spain), GenOMICC Consortium, Japan COVID-19 Task Force, Regeneron Genetics Center, Daniel H Geschwind, Stephanie Arteaga, Alexis Stephens, Manish J Butte, Paul C Boutros, Takafumi N Yamaguchi, Shu Tao, Stefan Eng, Timothy Sanders, Paul J Tung, Michael E Broudy, Yu Pan, Alfredo Gonzalez, Nikhil Chavan, Ruth Johnson, Bogdan Pasaniuc, Brian Yaspan, Sandra Smieszek, Carlo Rivolta, Stephanie Bibert, Pierre-Yves Bochud, Maciej Dabrowski, Pawel Zawadzki, Mateusz Sypniewski, Elżbieta Kaja, Pajaree Chariyavilaskul, Voraphoj Nilaratanakul, Nattiya Hirankarn, Vorasuk Shotelersuk, Monnat Pongpanich, Chureerat Phokaew, Wanna Chetruengchai, Katsushi Tokunaga, Masaya Sugiyama, Yosuke Kawai, Takanori Hasegawa, Tatsuhiko Naito, Ho Namkoong, Ryuya Edahiro, Akinori Kimura, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada, Seiya Imoto, Satoru Miyano, Serghei Mangul, Malak S Abedalthagafi, Hugo Zeberg, Joseph J Grzymski, Nicole L Washington, Stephan Ossowski, Kerstin U Ludwig, Eva C Schulte, Olaf Riess, Marcin Moniuszko, Miroslaw Kwasniewski, Hamdi Mbarek, Said I Ismail, Anurag Verma, David B Goldstein, Krzysztof Kiryluk, Alessandra Renieri, Manuel A R Ferreira, J Brent Richards
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010367 (2022)
Host genetics is a key determinant of COVID-19 outcomes. Previously, the COVID-19 Host Genetics Initiative genome-wide association study used common variants to identify multiple loci associated with COVID-19 outcomes. However, variants with the larg
Externí odkaz:
https://doaj.org/article/5f79e367675d482a9faf89902afbc030
Autor:
Irene V. van Blokland, Pauline Lanting, Anil P. S. Ori, Judith M. Vonk, Robert C. A. Warmerdam, Johanna C. Herkert, Floranne Boulogne, Annique Claringbould, Esteban A. Lopera-Maya, Meike Bartels, Jouke-Jan Hottenga, Andrea Ganna, Juha Karjalainen, Lifelines COVID-19 cohort study, The COVID-19 Host Genetics Initiative, Caroline Hayward, Chloe Fawns-Ritchie, Archie Campbell, David Porteous, Elizabeth T. Cirulli, Kelly M. Schiabor Barrett, Stephen Riffle, Alexandre Bolze, Simon White, Francisco Tanudjaja, Xueqing Wang, Jimmy M. Ramirez, Yan Wei Lim, James T. Lu, Nicole L. Washington, Eco J. C. de Geus, Patrick Deelen, H. Marike Boezen, Lude H. Franke
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Epidemiological and genetic studies on COVID-19 are currently hindered by inconsistent and limited testing policies to confirm SARS-CoV-2 infection. Recently, it was shown that it is possible to predict COVID-19 cases using cross-sectional self-repor
Externí odkaz:
https://doaj.org/article/48e7e653327e48aabd22b8438d85070f
Autor:
Stephen Riffle, Rashmi S. Hegde
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-10 (2017)
Abstract Under hypoxic conditions, tumor cells undergo a series of adaptations that promote evolution of a more aggressive tumor phenotype including the activation of DNA damage repair proteins, altered metabolism, and decreased proliferation. Togeth
Externí odkaz:
https://doaj.org/article/2f778e9e87574c7da08612be8cccc492
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Multicellular Tumor Spheroids are frequently used to mimic the regionalization of proliferation and the hypoxic environment within avascular tumors. Here we exploit these features to study the activation of DNA damage repair pathw
Externí odkaz:
https://doaj.org/article/c9831c76c4dc476b9699c410ecc5e272
Autor:
Rashmi S. Hegde, Kathryn A. Wikenheiser-Brokamp, Hemabindu Chintala, Stephen Riffle, Ram Naresh Pandey, Yuhua Wang
Tamoxifen-induced loss of EYA3 protein in the tumor vasculature of Eya3VEC-KO mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a5ec5bec139d173b63932bb48bd4b2
https://doi.org/10.1158/1535-7163.22504920.v1
https://doi.org/10.1158/1535-7163.22504920.v1
Autor:
Rashmi S. Hegde, Kathryn A. Wikenheiser-Brokamp, Hemabindu Chintala, Stephen Riffle, Ram Naresh Pandey, Yuhua Wang
DNA damage repair capacity is required for cells to survive catastrophic DNA damage and proliferate under conditions of intratumoral stress. The ability of the minor histone protein H2AX to serve as a hub for the assembly of a productive DNA damage r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a09d758f664c7a2be66bcc527f5ebb5
https://doi.org/10.1158/1535-7163.c.6537897.v1
https://doi.org/10.1158/1535-7163.c.6537897.v1
Autor:
Caroline Hayward, Lude Franke, Francisco Tanudjaja, Meike Bartels, Chloe Fawns-Ritchie, Jimmy M. Ramirez, Kelly M. Schiabor Barrett, David J. Porteous, Patrick Deelen, Jouke-Jan Hottenga, Xueqing Wang, Simon D. M. White, Nicole L. Washington, Floranne Boulogne, Andrea Ganna, Esteban A. Lopera-Maya, Robert Warmerdam, Anil P.S. Ori, Alexandre Bolze, Elizabeth T. Cirulli, Stephen Riffle, Archie Campbell, Annique Claringbould, Eco J. C. de Geus, Johanna C. Herkert, Judith M. Vonk, H. Marike Boezen, Irene V. van Blokland, James T. Lu, Yan Wei Lim, Juha Karjalainen, Pauline Lanting
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255402 (2021)
van Blokland, I V, Lanting, P, Ori, A P S, Vonk, J M, Warmerdam, R C A, Herkert, J C, Boulogne, F, Claringbould, A, Lopera-Maya, E A, Bartels, M, Hottenga, J J, Ganna, A, Karjalainen, J, Hayward, C, Fawns-Ritchie, C, Campbell, A, Porteous, D, Cirulli, E T, Barrett, K M S, Riffle, S, Bolze, A, White, S, Tanudjaja, F, Wang, X, Ramirez, J M, Lim, Y W, Lu, J T, Washington, N L, de Geus, E J C & Deelen, P & Boezen, H M & Franke, L H 2021, ' Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility ', PLoS ONE, vol. 16, no. 8, e0255402 . https://doi.org/10.1371/journal.pone.0255402
PLoS ONE, 16(8):e0255402. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 16, Iss 8 (2021)
van Blokland, I V, Lanting, P, Ori, A P S, Vonk, J M, Warmerdam, R C A, Herkert, J C, Boulogne, F, Claringbould, A, Lopera-Maya, E A, Bartels, M, Hottenga, J J, Ganna, A, Karjalainen, J, Hayward, C, Fawns-Ritchie, C, Campbell, A, Porteous, D, Cirulli, E T, Barrett, K M S, Riffle, S, Bolze, A, White, S, Tanudjaja, F, Wang, X, Ramirez, J M, Lim, Y W, Lu, J T, Washington, N L, de Geus, E J C, Deelen, P, Boezen, H M & Franke, L H 2021, ' Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility ', PLoS ONE, vol. 16, no. 8, e0255402, pp. 1-18 . https://doi.org/10.1371/journal.pone.0255402
PLoS ONE, 16(8):e0255402, 1-18. Public Library of Science
PLoS ONE
van Blokland, I V, Lanting, P, Ori, A P S, Vonk, J M, Warmerdam, R C A, Herkert, J C, Boulogne, F, Claringbould, A, Lopera-Maya, E A, Bartels, M, Hottenga, J J, Ganna, A, Karjalainen, J, Hayward, C, Fawns-Ritchie, C, Campbell, A, Porteous, D, Cirulli, E T, Barrett, K M S, Riffle, S, Bolze, A, White, S, Tanudjaja, F, Wang, X, Ramirez, J M, Lim, Y W, Lu, J T, Washington, N L, de Geus, E J C & Deelen, P & Boezen, H M & Franke, L H 2021, ' Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility ', PLoS ONE, vol. 16, no. 8, e0255402 . https://doi.org/10.1371/journal.pone.0255402
PLoS ONE, 16(8):e0255402. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 16, Iss 8 (2021)
van Blokland, I V, Lanting, P, Ori, A P S, Vonk, J M, Warmerdam, R C A, Herkert, J C, Boulogne, F, Claringbould, A, Lopera-Maya, E A, Bartels, M, Hottenga, J J, Ganna, A, Karjalainen, J, Hayward, C, Fawns-Ritchie, C, Campbell, A, Porteous, D, Cirulli, E T, Barrett, K M S, Riffle, S, Bolze, A, White, S, Tanudjaja, F, Wang, X, Ramirez, J M, Lim, Y W, Lu, J T, Washington, N L, de Geus, E J C, Deelen, P, Boezen, H M & Franke, L H 2021, ' Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility ', PLoS ONE, vol. 16, no. 8, e0255402, pp. 1-18 . https://doi.org/10.1371/journal.pone.0255402
PLoS ONE, 16(8):e0255402, 1-18. Public Library of Science
PLoS ONE
Epidemiological and genetic studies on COVID-19 are currently hindered by inconsistent and limited testing policies to confirm SARS-CoV-2 infection. Recently, it was shown that it is possible to predict COVID-19 cases using cross-sectional self-repor
Autor:
Kelly M. Schiabor Barrett, Nicole L. Washington, James T. Lu, Shaun Dabe, Elizabeth T. Cirulli, Stephen Riffle, Alexandre Bolze, Iva Neveux, Joseph J. Grzymski
It is increasingly recognized that SARS-CoV-2 can produce long-term complications after recovery from the acute effects of infection. Here, we report the analysis of 32 self-reported short and long-term symptoms in a general adult population cohort c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d4b822d4320655b8b1c1fa4188bf94
https://doi.org/10.1101/2020.10.07.20208702
https://doi.org/10.1101/2020.10.07.20208702
Lay summaryOur researchers took a look at a sequence of DNA known as the ACE2 gene. This gene is most well known for its role in regulating blood pressure. But in recent times, it’s drawn a lot of attention from the scientific community because it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8164c7965f1225aec92fa7cb5d55b589
Autor:
Kathryn A. Wikenheiser-Brokamp, Rashmi S. Hegde, Stephen Riffle, Ram Naresh Pandey, Hemabindu Chintala, Yuhua Wang
Publikováno v:
Molecular Cancer Therapeutics. 17:1659-1669
DNA damage repair capacity is required for cells to survive catastrophic DNA damage and proliferate under conditions of intratumoral stress. The ability of the minor histone protein H2AX to serve as a hub for the assembly of a productive DNA damage r