Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Stephen, Lory"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Protein Hfq regulates bacterial mRNA translation and stability by interacting with mRNAs and small noncoding RNAs. Here, the authors identify Hfq-interacting RNAs in three strains representing major phylogenetic lineages of Pseudomonas aeruginosa, hi
Externí odkaz:
https://doaj.org/article/d829dbb6db904995a46a0e2285709659
Autor:
Kook Han, Stephen Lory
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
With the recognition of the importance of posttranscriptional regulation mediated by bacterial small RNAs (sRNAs), their contribution to global gene expression regulatory networks needs to be addressed in a truly comprehensive manner. While a single
Externí odkaz:
https://doaj.org/article/fc149ce2bbb84da79d54488e4227a9c5
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Biogenesis of the outer membrane of Gram-negative bacteria depends on dedicated macromolecular transport systems. The LolABCDE proteins make up the machinery for lipoprotein trafficking from the inner membrane (IM) across the periplasm to th
Externí odkaz:
https://doaj.org/article/924bf0069511460596ca881bfcf7b2d0
Autor:
Pauline Basso, Michel Ragno, Sylvie Elsen, Emeline Reboud, Guillaume Golovkine, Stephanie Bouillot, Philippe Huber, Stephen Lory, Eric Faudry, Ina Attrée
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Clinical strains of Pseudomonas aeruginosa lacking the type III secretion system genes employ a toxin, exolysin (ExlA), for host cell membrane disruption. Here, we demonstrated that ExlA export requires a predicted outer membrane protein, Ex
Externí odkaz:
https://doaj.org/article/f6d0809c3fa644599ba0f26864033712
Autor:
Fiona S L, Brinkman, Geoffrey L, Winsor, Rachel E, Done, Alain, Filloux, Vanessa I, Francis, Joanna B, Goldberg, E Peter, Greenberg, Kook, Han, Robert E W, Hancock, Cara H, Haney, Susanne, Häußler, Jens, Klockgether, Iain L, Lamont, Roger C, Levesque, Stephen, Lory, Pablo I, Nikel, Steven L, Porter, Matthew W, Scurlock, Herbert P, Schweizer, Burkhard, Tümmler, Meng, Wang, Martin, Welch
Publikováno v:
Advances in microbial physiology. 79
Toward the end of August 2000, the 6.3 Mbp whole genome sequence of Pseudomonas aeruginosa strain PAO1 was published. With 5570 open reading frames (ORFs), PAO1 had the largest microbial genome sequenced up to that point in time-including a large pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::289733a89dc77866f8f37f1852706d9c
https://pubmed.ncbi.nlm.nih.gov/34836612
https://pubmed.ncbi.nlm.nih.gov/34836612
Publikováno v:
Nature Communications, 13
Nature Communications
Nature Communications, 2022, 13 (1), pp.1258. ⟨10.1038/s41467-022-28849-w⟩
Nature Communications
Nature Communications, 2022, 13 (1), pp.1258. ⟨10.1038/s41467-022-28849-w⟩
The major RNA-binding protein Hfq interacts with mRNAs, either alone or together with regulatory small noncoding RNAs (sRNAs), affecting mRNA translation and degradation in bacteria. However, studies tend to focus on single reference strains and assu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e803b67d77e6e9854f61e450b4eba1
https://pubmed.ncbi.nlm.nih.gov/35273147
https://pubmed.ncbi.nlm.nih.gov/35273147
Autor:
Stephen Lory, Kook Han
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
mBio
mBio
A number of computational or experimental tools have been developed to identify targets of small RNA (sRNA) regulation. Here, we modified one of these methods, based on in vivo proximity ligation of sRNAs bound to their targets, referred to as rGRIL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d08f91f5f35c97e7869fcd3539c1f1
https://journals.asm.org/doi/10.1128/mBio.03608-20
https://journals.asm.org/doi/10.1128/mBio.03608-20
Autor:
Iain L. Lamont, Rachel E Done, Susanne Häußler, Fiona S. L. Brinkman, Meng Wang, Herbert P. Schweizer, Stephen Lory, Burkhard Tümmler, Jens Klockgether, E. Peter Greenberg, Geoffrey L. Winsor, Steven L. Porter, Martin Welch, Kook Han, Robert E. W. Hancock, Alain Filloux, Vanessa I Francis, Matthew W Scurlock, Pablo I. Nikel, Cara H. Haney, Joanna B. Goldberg, Roger C. Levesque
Publikováno v:
Advances in Microbial Physiology ISBN: 9780128246023
Toward the end of August 2000, the 6.3 Mbp whole genome sequence of Pseudomonas aeruginosa strain PAO1 was published. With 5570 open reading frames (ORFs), PAO1 had the largest microbial genome sequenced up to that point in time-including a large pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b8e9fa520b31608fbb0c1e5155d3864
https://doi.org/10.1016/bs.ampbs.2021.07.001
https://doi.org/10.1016/bs.ampbs.2021.07.001
Autor:
David Skurnik, Damien Roux, Hugues Aschard, Vincent Cattoir, Deborah Yoder-Himes, Stephen Lory, Gerald B Pier
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003582 (2013)
High-throughput sequencing of transposon (Tn) libraries created within entire genomes identifies and quantifies the contribution of individual genes and operons to the fitness of organisms in different environments. We used insertion-sequencing (INSe
Externí odkaz:
https://doaj.org/article/0cc76180d9a04d8ea2ad3f60a4ef40d3
Publikováno v:
Journal of Bacteriology
A key set of lipoprotein transport components, LolCDE, were inhibited by both a small molecule as well as genetic downregulation of their expression. The data show a unique signature in the Pseudomonas aeruginosa transcriptome in response to perturba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c0249e05824ff7d945cf13af44432a
https://doi.org/10.1128/jb.00452-20
https://doi.org/10.1128/jb.00452-20