VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function

Autor: Briston, Thomas, Stephen, Jenna M., Thomas, Luke W., Esposito, Cinzia, Chung, Yuen-Li, Syafruddin, Saiful E., Turmaine, Mark, Maddalena, Lucas A., Greef, Basma, Szabadkai, Gyorgy, Maxwell, Patrick H., Vanharanta, Sakari, Ashcroft, Margaret

Publikováno v: Frontiers in Oncology

Dysregulated mitochondrial function is associated with the pathology of a wide range of diseases including renal disease and cancer. Thus, investigating regulators of mitochondrial function is of particular interest. Previous work has shown that the

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https://www.repository.cam.ac.uk/handle/1810/285342

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Corrigendum: VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function.

Autor: Briston, Thomas, Stephen, Jenna M., Thomas, Luke W., Esposito, Cinzia, Chung, Yuen-Li, Syafruddin, Saiful E., Turmaine, Mark, Maddalena, Lucas A., Greef, Basma, Szabadkai, Gyorgy, Maxwell, Patrick H., Vanharanta, Sakari, Ashcroft, Margaret

Publikováno v: Frontiers in Oncology; 9/23/2021, Vol. 11, p1-2, 2p

CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism

Autor: Thomas, Luke W, Esposito, Cinzia, Stephen, Jenna M, Costa, Ana SH, Frezza, Christian, Blacker, Thomas S, Szabadkai, Gyorgy, Ashcroft, Margaret

BACKGROUND: Mitochondrial oxidative phosphorylation (OXPHOS) via the respiratory chain is required for the maintenance of tumour cell proliferation and regulation of epithelial to mesenchymal transition (EMT)-related phenotypes through mechanisms tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d22f9bfc2bde07032ead7af0afd8983e

VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function.

Autor: Briston T; Division of Medicine, Centre for Cell Signalling and Molecular Genetics, University College London, London, United Kingdom., Stephen JM; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Thomas LW; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Esposito C; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Chung YL; Cancer Research UK Cancer Imaging Centre, Institute of Cancer Research London, London, United Kingdom., Syafruddin SE; Medical Research Council Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom., Turmaine M; Division of Biosciences, Department of Cell and Developmental Biology, University College London, London, United Kingdom., Maddalena LA; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Greef B; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Szabadkai G; Division of Biosciences, Department of Cell and Developmental Biology, University College London, London, United Kingdom.; The Francis Crick Institute, London, United Kingdom.; Department of Biomedical Sciences, University of Padua, Padua, Italy., Maxwell PH; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom., Vanharanta S; Medical Research Council Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom., Ashcroft M; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: Frontiers in oncology [Front Oncol] 2018 Oct 04; Vol. 8, pp. 388. Date of Electronic Publication: 2018 Oct 04 (Print Publication: 2018).