Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Stephen, H Kazakoff"'
Autor:
David Fielding, Andrew J. Dalley, Mahendra Singh, Lakshmy Nandakumar, Vanessa Lakis, Haarika Chittoory, David Fairbairn, Ann-Marie Patch, Stephen H. Kazakoff, Kaltin Ferguson, Farzad Bashirzadeh, Michael Bint, Carl Pahoff, Jung Hwa Son, Kimberley Ryan, Alan Hodgson, Sowmya Sharma, John V. Pearson, Nicola Waddell, Sunil R. Lakhani, Gunter Hartel, Peter T. Simpson, Katia Nones
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionTumour Mutation Burden (TMB) is a potential biomarker for immune cancer therapies. Here we investigated parameters that might affect TMB using duplicate cytology smears obtained from endobronchial ultrasound transbronchial needle aspirati
Externí odkaz:
https://doaj.org/article/f59f51c4cc2242a2aa208dda6ce9e2fd
Autor:
Jenette Creaney, Ann-Marie Patch, Venkateswar Addala, Sophie A. Sneddon, Katia Nones, Ian M. Dick, Y. C. Gary Lee, Felicity Newell, Ebony J. Rouse, Marjan M. Naeini, Olga Kondrashova, Vanessa Lakis, Apostolos Nakas, David Waller, Annabel Sharkey, Pamela Mukhopadhyay, Stephen H. Kazakoff, Lambros T. Koufariotis, Aimee L. Davidson, Priya Ramarao-Milne, Oliver Holmes, Qinying Xu, Conrad Leonard, Scott Wood, Sean M. Grimmond, Raphael Bueno, Dean A. Fennell, John V. Pearson, Bruce W. Robinson, Nicola Waddell
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Malignant pleural mesothelioma (MPM) has a poor overall survival with few treatment options. Whole genome sequencing (WGS) combined with the immune features of MPM offers the prospect of identifying changes that could inform futur
Externí odkaz:
https://doaj.org/article/5bdff0d20d9746a283a822d97c8462e5
Autor:
Vanessa F. Bonazzi, Olga Kondrashova, Deborah Smith, Katia Nones, Asmerom T. Sengal, Robert Ju, Leisl M. Packer, Lambros T. Koufariotis, Stephen H. Kazakoff, Aimee L. Davidson, Priya Ramarao-Milne, Vanessa Lakis, Felicity Newell, Rebecca Rogers, Claire Davies, James Nicklin, Andrea Garrett, Naven Chetty, Lewis Perrin, John V. Pearson, Ann-Marie Patch, Nicola Waddell, Pamela M. Pollock
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Endometrial cancer (EC) is a major gynecological cancer with increasing incidence. It comprises four molecular subtypes with differing etiology, prognoses, and responses to chemotherapy. In the future, clinical trials testing new
Externí odkaz:
https://doaj.org/article/4b680dfc6fbc449d935cd19fb75a3b51
Autor:
Felicity Newell, James S. Wilmott, Peter A. Johansson, Katia Nones, Venkateswar Addala, Pamela Mukhopadhyay, Natasa Broit, Carol M. Amato, Robert Van Gulick, Stephen H. Kazakoff, Ann-Marie Patch, Lambros T. Koufariotis, Vanessa Lakis, Conrad Leonard, Scott Wood, Oliver Holmes, Qinying Xu, Karl Lewis, Theresa Medina, Rene Gonzalez, Robyn P. M. Saw, Andrew J. Spillane, Jonathan R. Stretch, Robert V. Rawson, Peter M. Ferguson, Tristan J. Dodds, John F. Thompson, Georgina V. Long, Mitchell P. Levesque, William A. Robinson, John V. Pearson, Graham J. Mann, Richard A. Scolyer, Nicola Waddell, Nicholas K. Hayward
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Acral melanoma occurs on the soles of the feet, palms of the hands and in nail beds. Here, the authors reports the genomic landscape of 87 acral melanomas and find that some tumors harbor a UV signature and that the tumors are diverse at the levels o
Externí odkaz:
https://doaj.org/article/953bcceaafac4fed9eb837e6a8612ce4
Autor:
Felicity Newell, Yan Kong, James S. Wilmott, Peter A. Johansson, Peter M. Ferguson, Chuanliang Cui, Zhongwu Li, Stephen H. Kazakoff, Hazel Burke, Tristan J. Dodds, Ann-Marie Patch, Katia Nones, Varsha Tembe, Ping Shang, Louise van der Weyden, Kim Wong, Oliver Holmes, Serigne Lo, Conrad Leonard, Scott Wood, Qinying Xu, Robert V. Rawson, Pamela Mukhopadhyay, Reinhard Dummer, Mitchell P. Levesque, Göran Jönsson, Xuan Wang, Iwei Yeh, Hong Wu, Nancy Joseph, Boris C. Bastian, Georgina V. Long, Andrew J. Spillane, Kerwin F. Shannon, John F. Thompson, Robyn P. M. Saw, David J. Adams, Lu Si, John V. Pearson, Nicholas K. Hayward, Nicola Waddell, Graham J. Mann, Jun Guo, Richard A. Scolyer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Mucosal melanomas are challenging to treat partly because so little is known about the genetic drivers underpinning them. Here, the authors perform a genomic landscape analysis of samples collected from three continents, revealing a potential role fo
Externí odkaz:
https://doaj.org/article/2e6c660727314c7ebfed4a9f82ef05a8
Autor:
Felicity Newell, Kalpana Patel, Michael Gartside, Lutz Krause, Sandra Brosda, Lauren G. Aoude, Kelly A. Loffler, Vanessa F. Bonazzi, Ann-Marie Patch, Stephen H. Kazakoff, Oliver Holmes, Qinying Xu, Scott Wood, Conrad Leonard, Guy Lampe, Reginald V. Lord, David C. Whiteman, John V. Pearson, Katia Nones, Nicola Waddell, Andrew P. Barbour
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Background Oesophageal adenocarcinoma (EAC) incidence is increasing and has a poor survival rate. Barrett’s oesophagus (BE) is a precursor condition that is associated with EAC and often occurs in conjunction with chronic gastro-oesophagea
Externí odkaz:
https://doaj.org/article/d3f969ebfdee44c79042fd747735c98a
Autor:
Jessamine E Hazlewood, Troy Dumenil, Thuy T Le, Andrii Slonchak, Stephen H Kazakoff, Ann-Marie Patch, Lesley-Ann Gray, Paul M Howley, Liang Liu, John D Hayball, Kexin Yan, Daniel J Rawle, Natalie A Prow, Andreas Suhrbier
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009215 (2021)
Poxvirus systems have been extensively used as vaccine vectors. Herein a RNA-Seq analysis of intramuscular injection sites provided detailed insights into host innate immune responses, as well as expression of vector and recombinant immunogen genes,
Externí odkaz:
https://doaj.org/article/51873aa015164c15b3f0332db477b26b
Autor:
Felicity Newell, Peter A. Johansson, James S. Wilmott, Katia Nones, Vanessa Lakis, Antonia L. Pritchard, Serigne N. Lo, Robert V. Rawson, Stephen H. Kazakoff, Andrew J. Colebatch, Lambros T. Koufariotis, Peter M. Ferguson, Scott Wood, Conrad Leonard, Matthew H. Law, Kelly M. Brooks, Natasa Broit, Jane M. Palmer, Kasey L. Couts, Ismael A. Vergara, Georgina V. Long, Andrew P. Barbour, Omgo E. Nieweg, Brindha Shivalingam, William A. Robinson, Jonathan R. Stretch, Andrew J. Spillane, Robyn P.M. Saw, Kerwin F. Shannon, John F. Thompson, Graham J. Mann, John V. Pearson, Richard A. Scolyer, Nicola Waddell, Nicholas K. Hayward
Publikováno v:
Cancer Discovery. 12:2856-2879
Melanoma is a cancer of melanocytes, with multiple subtypes based on body site location. Cutaneous melanoma is associated with skin exposed to ultraviolet radiation; uveal melanoma occurs in the eyes; mucosal melanoma occurs in internal mucous membra
Autor:
Nicholas K. Hayward, Nicola Waddell, Richard A. Scolyer, John V. Pearson, Graham J. Mann, John F. Thompson, Kerwin F. Shannon, Robyn P.M. Saw, Andrew J. Spillane, Jonathan R. Stretch, William A. Robinson, Brindha Shivalingam, Omgo E. Nieweg, Andrew P. Barbour, Georgina V. Long, Ismael A. Vergara, Kasey L. Couts, Jane M. Palmer, Natasa Broit, Kelly M. Brooks, Matthew H. Law, Conrad Leonard, Scott Wood, Peter M. Ferguson, Lambros T. Koufariotis, Andrew J. Colebatch, Stephen H. Kazakoff, Robert V. Rawson, Serigne N. Lo, Antonia L. Pritchard, Vanessa Lakis, Katia Nones, James S. Wilmott, Peter A. Johansson, Felicity Newell
Supplementary Data from Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039a2ce67c76ce6b5dc56b00dcb51d0e
https://doi.org/10.1158/2159-8290.22541617.v1
https://doi.org/10.1158/2159-8290.22541617.v1
Autor:
Nicholas K. Hayward, Nicola Waddell, Richard A. Scolyer, John V. Pearson, Graham J. Mann, John F. Thompson, Kerwin F. Shannon, Robyn P.M. Saw, Andrew J. Spillane, Jonathan R. Stretch, William A. Robinson, Brindha Shivalingam, Omgo E. Nieweg, Andrew P. Barbour, Georgina V. Long, Ismael A. Vergara, Kasey L. Couts, Jane M. Palmer, Natasa Broit, Kelly M. Brooks, Matthew H. Law, Conrad Leonard, Scott Wood, Peter M. Ferguson, Lambros T. Koufariotis, Andrew J. Colebatch, Stephen H. Kazakoff, Robert V. Rawson, Serigne N. Lo, Antonia L. Pritchard, Vanessa Lakis, Katia Nones, James S. Wilmott, Peter A. Johansson, Felicity Newell
Melanoma is a cancer of melanocytes, with multiple subtypes based on body site location. Cutaneous melanoma is associated with skin exposed to ultraviolet radiation; uveal melanoma occurs in the eyes; mucosal melanoma occurs in internal mucous membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3d732adf31f4564decd8911f07bea9
https://doi.org/10.1158/2159-8290.c.6549709
https://doi.org/10.1158/2159-8290.c.6549709