Follicle-Stimulating Hormone Induces Lipid Droplets via Gαi/o and β-Arrestin in an Endometrial Cancer Cell Line

Autor: Niamh S. Sayers, Priyanka Anujan, Henry N. Yu, Stephen S. Palmer, Jaya Nautiyal, Stephen Franks, Aylin C. Hanyaloglu

Publikováno v: Frontiers in Endocrinology, Vol 12 (2022)

Follicle-stimulating hormone (FSH) and its G protein-coupled receptor, FSHR, represents a paradigm for receptor signaling systems that activate multiple and complex pathways. Classically, FSHR activates Gαs to increase intracellular levels of cAMP,

Externí odkaz: https://doaj.org/article/68b2b6b7698f46bb95b942fa91ee3022

Insights into Manipulating Postprandial Energy Expenditure to Manage Weight Gain in Polycystic Ovary Syndrome

Autor: Katarzyna Siemienowicz, Michael T. Rae, Fiona Howells, Chloe Anderson, Linda M. Nicol, Stephen Franks, William C. Duncan

Publikováno v: iScience, Vol 23, Iss 6, Pp 101164- (2020)

Summary: Women with polycystic ovary syndrome (PCOS) are more likely to be obese and have difficulty in losing weight. They demonstrate an obesity-independent deficit in adaptive energy expenditure. We used a clinically realistic preclinical model to

Externí odkaz: https://doaj.org/article/65b07f3771c544dbb4583db245f77b9c

Effect of polycystic ovary syndrome on cardiac autonomic function at a late fertile age: a prospective Northern Finland Birth Cohort 1966 study

Autor: Elisabet Stener-Victorin, Meri-Maija Ollila, Antti Kiviniemi, Mikko Tulppo, Katri Puukka, Juha Tapanainen, Stephen Franks, Laure Morin-Papunen, Terhi Piltonen

Publikováno v: BMJ Open, Vol 9, Iss 12 (2019)

Objectives Previous studies of women in their 20s and 30s have reported impaired autonomic function in women with polycystic ovary syndrome (PCOS). We aimed to study, for the first time, whether PCOS is associated with impaired cardiac autonomic func

Externí odkaz: https://doaj.org/article/618bee619ce343678adaaddc39d04e26

Dopamine transporter activity regulates neuroimmune communication

Autor: Adithya Gopinath, Phillip M. Mackie, Emily Miller, Leah T. Phan, Stephen Franks, Tabish Riaz, Aidan R. Smith, Michael Okun, Habibeh Khoshbouei

Publikováno v: ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::960a762cda8c39e8c8c152b9a32bf7bb
https://doi.org/10.1124/jpet.122.523230

Intrafollicular Concentrations of the Oocyte-secreted Factors GDF9 and BMP15 Vary Inversely in Polycystic Ovaries

Autor: Stine Gry Kristensen, Ajay Kumar, Linn Salto Mamsen, Bhanu Kalra, Susanne Elisabeth Pors, Jane Alrø Bøtkjær, Kirsten Tryde Macklon, Jens Fedder, Erik Ernst, Kate Hardy, Stephen Franks, Claus Yding Andersen

Publikováno v: E3383
E3374
Kristensen, S G, Kumar, A, Mamsen, L S, Kalra, B, Pors, S E, Bøtkjær, J A, Macklon, K T, Fedder, J, Ernst, E, Hardy, K, Franks, S & Andersen, C Y 2022, ' Intrafollicular Concentrations of the Oocyte-secreted Factors GDF9 and BMP15 Vary Inversely in Polycystic Ovaries ', The Journal of Clinical Endocrinology & Metabolism, vol. 107, no. 8, pp. e3374-e3383 . https://doi.org/10.1210/clinem/dgac272
Kristensen, S G, Kumar, A, Mamsen, L S, Kalra, B, Pors, S E, Bøtkjær, J A, Macklon, K T, Fedder, J, Ernst, E, Hardy, K, Franks, S & Andersen, C Y 2022, ' Intrafollicular Concentrations of the Oocytesecreted Factors GDF9 and BMP15 Vary Inversely in Polycystic Ovaries ', Journal of Clinical Endocrinology and Metabolism, vol. 107, no. 8, pp. E3374-E3383 . https://doi.org/10.1210/clinem/dgac272

Context The oocyte-secreted factors growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) play essential roles in follicle development and oocyte maturation, and aberrant regulation might contribute to the pathogenesis of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b977d4cedec2e54f5ca12fcb36babf63
https://doi.org/10.1210/clinem/dgac272