Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Stephen, Barnard"'
Autor:
Mingzhu Sun, Jayne Moquet, Stephen Barnard, Hannah Mancey, David Burling, Rachel Baldwin-Cleland, Kevin Monahan, Andrew Latchford, David Lloyd, Simon Bouffler, Christophe Badie, Nicola A. Anyamene, Elizabeth Ainsbury
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionLynch syndrome patients have an inherited predisposition to cancer due to a deficiency in DNA mismatch repair (MMR) genes which could lead to a higher risk of developing cancer if exposed to ionizing radiation. This pilot study aims to re
Externí odkaz:
https://doaj.org/article/86c916560bf94bc1b6d2016778797f8d
Autor:
Alice Uwineza, Ian Cummins, Miguel Jarrin, Alexia A. Kalligeraki, Stephen Barnard, Marco Mol, Genny Degani, Alessandra A. Altomare, Giancarlo Aldini, An Schreurs, Detlef Balschun, Elizabeth A. Ainsbury, Irundika HK Dias, Roy A. Quinlan
Publikováno v:
Advances in Redox Research, Vol 7, Iss , Pp 100057- (2023)
Ionising radiation (IR) is a cause of lipid peroxidation, and epidemiological data have revealed a correlation between exposure to IR and the development of eye lens cataracts. Cataracts remain the leading cause of blindness around the world. The pla
Externí odkaz:
https://doaj.org/article/909a757273cb4520b74c0f1bdaf82b5f
Autor:
Jayne Moquet, Elizabeth Ainsburym, Katalin Balázs, Stephen Barnard, Rositsa Hristova, Katlin Lumniczky, Matthias Port, Ute Roessler, Harry Scherthan, Albena Staynova, Tünde Szatmári, Maria Wojewodzka, Michael Abend
Publikováno v:
Radiation Research.
The Running the European Network of biological and retrospective dosimetry (RENEB) network of laboratories has a range of biological and physical dosimetry assays that can be deployed in the event of a radiation incident to provide exposure assessmen
Autor:
Jochen Einbeck, Elizabeth A Ainsbury, Rachel Sales, Stephen Barnard, Felix Kaestle, Manuel Higueras
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207464 (2018)
Over the last decade, the γ-H2AX focus assay, which exploits the phosphorylation of the H2AX histone following DNA double-strand-breaks, has made considerable progress towards acceptance as a reliable biomarker for exposure to ionizing radiation. Wh
Externí odkaz:
https://doaj.org/article/c308fd5f8def455c836f82039781c5fc
Autor:
Elizabeth A. Ainsbury, Jayne Moquet, Mingzhu Sun, Stephen Barnard, David Lloyd, Michele Ellender
Publikováno v:
International Journal of Radiation Biology. 98:421-427
Purpose The aim of this brief personal, high level review is to consider the state of the art for biological dosimetry for radiation routine and emergency response, and the potential future progress in this fascinating and active field. Four areas in
Autor:
Nobuyuki Hamada, Stephen Barnard
Publikováno v:
International journal of radiation biology.
Cataract (opacification of the ocular lens) is a typical tissue reaction (deterministic effect) following ionizing radiation exposure, for which prevention dose limits have been recommended in the radiation protection system. Manifestations of radiat
Autor:
Ewa Markiewicz, Stephen Barnard, Jackie Haines, Margaret Coster, Orry van Geel, Weiju Wu, Shane Richards, Elizabeth Ainsbury, Kai Rothkamm, Simon Bouffler, Roy A. Quinlan
Publikováno v:
Open Biology, Vol 5, Iss 4 (2015)
Elevated cataract risk after radiation exposure was established soon after the discovery of X-rays in 1895. Today, increased cataract incidence among medical imaging practitioners and after nuclear incidents has highlighted how little is still unders
Externí odkaz:
https://doaj.org/article/4e5211e9d0c04347bacf7982eda8c5a7
Publikováno v:
PeerJ, Vol 2, p e282 (2014)
Following a radiation incident, preliminary dose estimates made by γ-H2AX foci analysis can supplement the early triage of casualties based on clinical symptoms. Sample processing time is important when many individuals need to be rapidly assessed.
Externí odkaz:
https://doaj.org/article/2b5ba7be6d47423fadfce0f9f74a7a6e
Autor:
A Uwineza, R McCarron, Alexia A. Kalligeraki, Stephen Barnard, Roy A. Quinlan, F Kruse, Elizabeth A. Ainsbury
Publikováno v:
Radiation Research. 197
Lens epithelial cell proliferation and differentiation are naturally well regulated and controlled, a characteristic essential for lens structure, symmetry and function. The effect of ionizing radiation on lens epithelial cell proliferation has been
Autor:
Elizabeth A. Ainsbury, Stephen Barnard
Publikováno v:
Experimental eye research. 212
When managed with appropriate radiation protection procedures, ionising radiation is of great benefit to society. Opacification of the lens, and vision impairing cataract, have recently been recognised at potential effects of relatively low dose radi