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of 3
pro vyhledávání: '"Stephanie-Anna Holzhüter"'
Autor:
Julia Bischof, Sarah Müller, Luise Borufka, Farahnaz Asghari, Steffen Möller, Stephanie-Anna Holzhüter, Horst Nizze, Saleh M Ibrahim, Robert Jaster
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136298 (2015)
The mouse strain MRL/MpJ is prone to spontaneously develop autoimmune pancreatitis (AIP). To elucidate the genetic control towards the development of the phenotype and to characterize contributions of immunocompetent cell types, MRL/MpJ mice were int
Externí odkaz:
https://doaj.org/article/4e032575d43347e9a1c70ae7174f749e
Autor:
Horst Nizze, Stephanie-Anna Holzhüter, Brit Fitzner, Peter Brock, Gisela Sparmann, Jörg Emmrich, Robert Jaster, Stefan Liebe
Publikováno v:
Digestive Diseases and Sciences. 54:309-320
Pancreatic stellate cells (PSC) play a key role in pancreatic fibrosis. Activation of PSC occurs in response to pro-fibrogenic stimuli and is maintained by autocrine loops of mediators, such as endothelin (ET)-1. Here, we have evaluated effects of th
Autor:
Steffen Möller, Stephanie-Anna Holzhüter, Robert Jaster, Horst Nizze, Saleh M. Ibrahim, Susen Müller, Andreia de Castro Marques, Farahnaz Asghari, Brit Fitzner
Publikováno v:
Journal of medical genetics. 48(8)
Background and aims Autoimmune pancreatitis (AIP) represents a rare but clinically relevant cause of pancreatic inflammation. Using MRL/Mp mice as a model of spontaneous AIP, the genetic basis of the disease was studied. Methods To identify quantitat