Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephanie W. L. Chu"'
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Peripheral iridectomy (PI), routinely performed during glaucoma filtration surgery, may contribute to scarring. This study aims to determine whether PI alters the concentrations of VEGF-A and TGF-β isoforms in the rabbit aqueous
Externí odkaz:
https://doaj.org/article/92c25db14bd14c79b847de97cddc8767
Autor:
Yong Yao Chun, Zhu Li Yap, Li Fong Seet, Hiok Hong Chan, Li Zhen Toh, Stephanie W. L. Chu, Ying Shi Lee, Tina T. Wong, Timothy T. Y. Tan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Small interfering RNA (siRNA) therapy is a promising epigenetic silencing strategy. However, its widespread adoption has been severely impeded by its ineffective delivery into the cellular environment. Here, a biocompatible injectable gelati
Externí odkaz:
https://doaj.org/article/6e9d9e1df63743018713f7752bd1781a
Autor:
Li-Fong Seet, Li Zhen Toh, Stephanie W. L. Chu, Sharon N. Finger, Jocelyn L. L. Chua, Tina T. Wong
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 6, Pp 751-760 (2017)
Excessive accumulation of collagen is often used to assess the development of fibrosis. This study aims to identify collagen genes that define fibrosis in the conjunctiva following glaucoma filtration surgery (GFS). Using the mouse model of GFS, we h
Externí odkaz:
https://doaj.org/article/68c4ca46b7c44731b39d17441d4b0720
Autor:
Li-Fong Seet, Zhu Li Yap, Stephanie W. L. Chu, Li Zhen Toh, Farah Ilyana Ibrahim, Xiao Teng, Tina T. Wong
Publikováno v:
Translational Vision Science & Technology
Purpose This study aimed to compare the effectiveness of combination therapy consisting of low-dose mitomycin C (MMC) and valproic acid (VPA) against high-dose MMC for improving the scar phenotype in minimally invasive glaucoma surgery (MIGS). Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5b40310aa40300043ef58ce4dfbad6
http://europepmc.org/articles/PMC8787605
http://europepmc.org/articles/PMC8787605
Publikováno v:
Anticancer research. 30(2)
Angiogenesis in the peritoneal cavity arising from ovarian cancer leads to peritoneal carcinomatosis, malignant ascites formation, morbidity and high mortality. Recent studies in our laboratory have shown albendazole (ABZ) to be a potent inhibitor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cea1e2e53a85d5527fc48e37017d41f9
https://pubmed.ncbi.nlm.nih.gov/20332449
https://pubmed.ncbi.nlm.nih.gov/20332449
Publikováno v:
Anticancer research. 29(10)
Resistance to paclitaxel (PTX) is a major concern in treating ovarian cancer. Thus, agents effective in taxane-resistant tumours are highly sought. It has recently been shown that albendazole (ABZ) is a potent inhibitor of cell proliferation, angioge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2843c04b2ebc6858a950df78ebdae38
https://pubmed.ncbi.nlm.nih.gov/19846910
https://pubmed.ncbi.nlm.nih.gov/19846910