Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephanie Vos"'
Autor:
Alexander Neumann, Olena Ohlei, Fahri Küçükali, Isabelle J. Bos, Jigyasha Timsina, Stephanie Vos, Dmitry Prokopenko, Betty M. Tijms, Ulf Andreasson, Kaj Blennow, Rik Vandenberghe, Philip Scheltens, Charlotte E. Teunissen, Sebastiaan Engelborghs, Giovanni B. Frisoni, Oliver Blin, Jill C. Richardson, Régis Bordet, Alberto Lleó, Daniel Alcolea, Julius Popp, Thomas W. Marsh, Priyanka Gorijala, Christopher Clark, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Richard J. B. Dobson, Cristina Legido-Quigley, Christine Van Broeckhoven, Rudolph E. Tanzi, Mara ten Kate, Christina M. Lill, Frederik Barkhof, Carlos Cruchaga, Simon Lovestone, Johannes Streffer, Henrik Zetterberg, Pieter Jelle Visser, Kristel Sleegers, Lars Bertram, EMIF-AD & ADNI study group
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-23 (2023)
Abstract Background Genome-wide association studies (GWAS) of Alzheimer’s disease (AD) have identified several risk loci, but many remain unknown. Cerebrospinal fluid (CSF) biomarkers may aid in gene discovery and we previously demonstrated that si
Externí odkaz:
https://doaj.org/article/f26d48a8fac447809738ca263de2f029
Autor:
Elles Konijnenberg, Betty M. Tijms, Johan Gobom, Valerija Dobricic, Isabelle Bos, Stephanie Vos, Magda Tsolaki, Frans Verhey, Julius Popp, Pablo Martinez-Lage, Rik Vandenberghe, Alberto Lleó, Lutz Frölich, Simon Lovestone, Johannes Streffer, Lars Bertram, Kaj Blennow, Charlotte E. Teunissen, Robert Veerhuis, August B. Smit, Philip Scheltens, Henrik Zetterberg, Pieter Jelle Visser
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Aggregation of amyloid β into plaques in the brain is one of the earliest pathological events in Alzheimer’s disease (AD). The exact pathophysiology leading to dementia is still uncertain, but the apolipoprotein E (APOE) ε4 ge
Externí odkaz:
https://doaj.org/article/a2719f0f9fab41c2bb1efa1068070aa7
Autor:
Claire Tochel, Michael Smith, Helen Baldwin, Anders Gustavsson, Amanda Ly, Christin Bexelius, Mia Nelson, Christophe Bintener, Enrico Fantoni, Josep Garre‐Olmo, Olin Janssen, Christoph Jindra, Isabella F. Jørgensen, Alex McKeown, Buket Öztürk, Anna Ponjoan, Michele H. Potashman, Catherine Reed, Emilse Roncancio‐Diaz, Stephanie Vos, Cathie Sudlow, the ROADMAP consortium
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 231-247 (2019)
Abstract Introduction Clinical trials involving patients with Alzheimer's disease (AD) continue to try to identify disease‐modifying treatments. Although trials are designed to meet regulatory and registration requirements, many do not measure outc
Externí odkaz:
https://doaj.org/article/57e677c42d614929bedcb9d26f020449
Autor:
Jaap Schuurmans, Romy Bouwmeester, Lamar Crombach, Tessa van Rijssel, Lizzy Wingens, Kristina Georgieva, Nadine O’Shea, Stephanie Vos, Bram Tilburgs, Yvonne Engels
Publikováno v:
BMC Medical Ethics, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background In the Netherlands, in 2002, euthanasia became a legitimate medical act, only allowed when the due care criteria and procedural requirements are met. Legally, an Advanced Euthanasia Directive (AED) can replace direct communication
Externí odkaz:
https://doaj.org/article/d1c0039e13c04f5d885f57a20ae4f96e
Autor:
Daniela Bertens, Stephanie Vos, Patrick Kehoe, Henrike Wolf, Flavio Nobili, Alexandre Mendonça, Ineke van Rossum, Jacub Hort, Jose Luis Molinuevo, Michael Heneka, Ron Petersen, Philip Scheltens, Pieter Jelle Visser
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2019)
Abstract Introduction The diagnosis of mild cognitive impairment (MCI) refers to cognitive impairment not meeting dementia criteria. A survey among members of the American Association of Neurology (AAN) showed that MCI was considered a useful diagnos
Externí odkaz:
https://doaj.org/article/87c0ca6ad013469f85147c58f24fbb07
Autor:
Isabelle Bos, Stephanie Vos, Rik Vandenberghe, Philip Scheltens, Sebastiaan Engelborghs, Giovanni Frisoni, José Luis Molinuevo, Anders Wallin, Alberto Lleó, Julius Popp, Pablo Martinez-Lage, Alison Baird, Richard Dobson, Cristina Legido-Quigley, Kristel Sleegers, Christine Van Broeckhoven, Lars Bertram, Mara ten Kate, Frederik Barkhof, Henrik Zetterberg, Simon Lovestone, Johannes Streffer, Pieter Jelle Visser
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-9 (2018)
Abstract Background There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer’s disease (AD) in the predementia stages and to predict the rate of decline. Therefore, we set up the European Medical Information Framework for Alz
Externí odkaz:
https://doaj.org/article/f1b06ad5df1d41228bd51b0b4f85d6f6
Autor:
Betty Marije Tijms, Johan Gobom, Charlotte Teunissen, Valerija Dobricic, Magda Tsolaki, Frans Verhey, Julius Popp, Pablo Martinez-Lage, Rik Vandenberghe, Alberto Lleó, José Luís Molinuévo, Sebastiaan Engelborghs, Yvonne Freund-Levi, Lutz Froelich, Lars Bertram, Simon Lovestone, Johannes Streffer, Stephanie Vos, ADNI, Kaj Blennow, Philip Scheltens, Henrik Zetterberg, Pieter Jelle Visser
Publikováno v:
Proteomes, Vol 9, Iss 3, p 36 (2021)
We recently discovered three distinct pathophysiological subtypes in Alzheimer’s disease (AD) using cerebrospinal fluid (CSF) proteomics: one with neuronal hyperplasticity, a second with innate immune system activation, and a third subtype with blo
Externí odkaz:
https://doaj.org/article/ebb8c4b24c124b4abfc43b06cd30834d
Autor:
Ron Handels, Sabine Grimm, Arjan Blokland, Nina Possemis, Inez Ramakers, Anke Sambeth, Frans Verhey, Stephanie Vos, Manuela Joore, Jos Prickaerts, Linus Jönsson
Publikováno v:
Alzheimer's & Dementia. Elsevier Science
INTRODUCTION: Early health-technology assessment can support discussing scarce resource allocation among stakeholders. We explored the value of maintaining cognition in patients with mild cognitive impairment (MCI) by estimating: (1) the innovation h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b39cafdcd89be3cabc74620d81b09c
https://doi.org/10.1002/alz.13001
https://doi.org/10.1002/alz.13001
Autor:
Alexander Neumann, Fahri Küçükali, Stephanie Vos, Dmitry Prokopenko, Betty Tijms, Rik Vandenberghe, Cristina Legido-Quigley
Genome-wide association studies (GWAS) of Alzheimer’s disease (AD) have identified several risk loci, but many remain unknown. Cerebrospinal fluid (CSF) biomarkers may aid in gene discovery and we previously demonstrated that six CSF biomarkers (β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::429646ec7c7e3f5df88968168a708b28
https://doi.org/10.1101/2022.08.02.22278185
https://doi.org/10.1101/2022.08.02.22278185
Autor:
Madison L. Doolittle, Dominik Saul, Japneet Kaur, Jennifer L. Rowsey, Brittany Eckhardt, Stephanie Vos, Sarah Grain, Kveta Kroupova, Ming Ruan, Megan Weivoda, Merry Jo Oursler, Joshua N. Farr, David G. Monroe, Sundeep Khosla
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 37(9)
Estrogen is known to regulate bone metabolism in both women and men, but substantial gaps remain in our knowledge of estrogen and estrogen receptor alpha (ERα) regulation of adult bone metabolism. Studies using global ERα-knockout mice were confoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a1ca971724306a9305746f3ce92bc7
https://pubmed.ncbi.nlm.nih.gov/35789113
https://pubmed.ncbi.nlm.nih.gov/35789113