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Real-World Use of Azathioprine Metabolites Changes Clinical Management of Inflammatory Bowel Disease
Publikováno v:
Journal of the Canadian Association of Gastroenterology
Background Thiopurines such as 6-mercaptopurine and azathioprine have complex metabolism, resulting in significant inter-individual differences in clinical efficacy and risk of drug toxicity, making conventional weight-based dosing inaccurate and pot