Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stephanie Tennstedt"'
Autor:
Viktor Verovenko, Stephanie Tennstedt, Mariana Kleinecke, Thorsten Kessler, Heribert Schunkert, Jeanette Erdmann, Stephan Ensminger, Zouhair Aherrahrou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract A positive family history is a major independent risk factor for atherosclerosis, and genetic variation is an important aspect of cardiovascular disease research. We identified a heterozygous missense variant p.L245P in the MMP10 gene in two
Externí odkaz:
https://doaj.org/article/4e316c6b171f422fb36a6eafe2c9d620
Autor:
Shafaq Ramzan, Stephanie Tennstedt, Muhammad Tariq, Sheraz Khan, Hafiza Noor Ul Ayan, Aamir Ali, Matthias Munz, Holger Thiele, Asad Aslam Korejo, Abdul Razzaq Mughal, Syed Zahid Jamal, Peter Nürnberg, Shahid Mahmood Baig, Jeanette Erdmann, Ilyas Ahmad
Publikováno v:
Genes, Vol 12, Iss 8, p 1282 (2021)
Cardiac conduction disease (CCD), which causes altered electrical impulse propagation in the heart, is a life-threatening condition with high morbidity and mortality. It exhibits genetic and clinical heterogeneity with diverse pathomechanisms, but in
Externí odkaz:
https://doaj.org/article/f98553ccec044f778915ddefd35dae10
Autor:
Heribert Schunkert, Jeanette Erdmann, Stephanie Tennstedt, Jana Wobst, Thomas Meitinger, Tim M. Strom, Hendrik B. Sager, Tan An Dang, Michael Wierer, Ingrid Braenne, Thorsten Kessler
Publikováno v:
Circulation 144, 662-665 (2021)
Autor:
Victor, Krajka, Franca, Vulinovic, Mariya, Genova, Kerstin, Tanzer, A S, Jijumon, Satish, Bodakuntla, Stephanie, Tennstedt, Helge, Mueller-Fielitz, Britta, Meier, Carsten, Janke, Christine, Klein, Aleksandar, Rakovic
Publikováno v:
Science advances. 8(10)
Mutations in the brain-specific β-tubulin 4A (TUBB4A) gene cause a broad spectrum of diseases, ranging from dystonia (DYT-TUBB4A) to hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC). Currently, the mechanisms of how
Autor:
Peter Nürnberg, Abdul Razzaq Mughal, Holger Thiele, Syed Zahid Jamal, Sheraz Jamal Khan, Shafaq Ramzan, Asad Aslam Korejo, Muhammad Tariq, Hafiza Noor Ul Ayan, Stephanie Tennstedt, Ilyas Ahmad, Shahid Mahmood Baig, Jeanette Erdmann, Aamir Ali, Matthias Munz
Publikováno v:
Genes
Volume 12
Issue 8
Genes, Vol 12, Iss 1282, p 1282 (2021)
Volume 12
Issue 8
Genes, Vol 12, Iss 1282, p 1282 (2021)
Cardiac conduction disease (CCD), which causes altered electrical impulse propagation in the heart, is a life-threatening condition with high morbidity and mortality. It exhibits genetic and clinical heterogeneity with diverse pathomechanisms, but in
Autor:
Birgit Assmann, Lara Lange, Stephanie Tennstedt, Sinem Tunc, Alexander Münchau, Christine Klein, Katja Lohmann
Publikováno v:
Movement Disorders. 32:1495-1497
Publikováno v:
Biochemical and Biophysical Research Communications. 471:380-385
Genome-wide association studies identified ADAMTS7 as a risk locus for coronary artery disease. In carotid arteries of rats, neointima formation after balloon-mediated injury goes along with enhanced Adamts7 expression. Vice versa, Adamts7-deficient
Autor:
Siegmund Braun, Heribert Schunkert, Andreas Friebe, Bernhard Wolf, Christian Hengstenberg, Simon von Ameln, Jeanette Erdmann, Tan An Dang, Michael Wierer, Jana Wobst, Stephanie Tennstedt, Doris Koesling, Thorsten Kessler, Hendrik B. Sager
Publikováno v:
Basic Research in Cardiology
Stimulators of the soluble guanylyl cyclase (sGC) are emerging therapeutic agents in cardiovascular diseases. Genetic alterations of the GUCY1A3 gene, which encodes the alpha(1) subunit of the sGC, are associated with coronary artery disease. Studies
Autor:
Julia A. Horsfield, Matthew A. Deardorff, Laura Daniela Michelis, Eva Rossier, Maren Mönnich, Robert G. Ramsay, María Concepción Gil-Rodríguez, Sara Halbach, Diana Braunholz, Dinah Clark, Emma Dickinson, Yuqian Yan, Abhinav Rampuria, Stephanie Tennstedt, Michael J. McKay, Stephanie Spranger, Sally Ann Lynch, Lionel Van Maldergem, Hermann-Josef Lüdecke, Gabriele Gillessen-Kaesbach, Ian D. Krantz, Huiling Xu, Melanie Albrecht, Jonathan J. Wilde, Hakon Hakonarson, Frank J. Kaiser, Weizhen Xu
Publikováno v:
The American Journal of Human Genetics. 90(6):1014-1027
The evolutionarily conserved cohesin complex was originally described for its role in regulating sister-chromatid cohesion during mitosis and meiosis. Cohesin and its regulatory proteins have been implicated in several human developmental disorders,
Autor:
Jana Wobst, Tan A Dang, Thorsten Kessler, Simon von Ameln, Stephanie Tennstedt, Christian Hengstenberg, Jeanette Erdmann, Heribert Schunkert
Publikováno v:
Circulation. 132
Introduction: Myocardial infarction (MI) is the main complication of coronary artery disease (CAD). Recently, a locus tagging the GUCY1A3 gene has been shown to be genome-wide significantly associated with CAD. GUCY1A3 encodes the α1 subunit of the