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of 6
pro vyhledávání: '"Stephanie T Kuwahara"'
Autor:
Stephanie T Kuwahara, Maxwell A Serowoky, Venus Vakhshori, Nikita Tripuraneni, Neel V Hegde, Jay R Lieberman, J Gage Crump, Francesca V Mariani
Publikováno v:
eLife, Vol 8 (2019)
Most bones in mammals display a limited capacity for natural large-scale repair. The ribs are a notable exception, yet the source of their remarkable regenerative ability remains unknown. Here, we identify a Sox9-expressing periosteal subpopulation t
Externí odkaz:
https://doaj.org/article/87b892502c6d429ab37bb0dfbb4a59c1
Autor:
Stephanie T. Kuwahara, Shuwan Liu, Andrew Chareunsouk, Maxwell Serowoky, Francesca V. Mariani
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract Uncovering the molecular pathways that drive skeletal repair has been an ongoing challenge. Initial efforts have relied on in vitro assays to identify the key signaling pathways that drive cartilage and bone differentiation. While these assa
Externí odkaz:
https://doaj.org/article/958dcde54b1f45e4a013d69b8748fd11
Autor:
Maxwell A. Serowoky, Stephanie T. Kuwahara, Shuwan Liu, Venus Vakhshori, Jay R. Lieberman, Francesca V. Mariani
Publikováno v:
npj Regenerative Medicine. 7
Building and maintaining skeletal tissue requires the activity of skeletal stem and progenitor cells (SSPCs). Following injury, local pools of these SSPCs become active and coordinate to build new cartilage and bone tissues. While recent studies have
Autor:
Stephanie T. Kuwahara, Shuwan Liu, Andrew Chareunsouk, Maxwell Serowoky, Francesca V. Mariani
Publikováno v:
Bone research. 10(1)
Uncovering the molecular pathways that drive skeletal repair has been an ongoing challenge. Initial efforts have relied on in vitro assays to identify the key signaling pathways that drive cartilage and bone differentiation. While these assays can pr
Autor:
Lynn Rowley, Thomas Pap, Karolina Kania, Maxwell A Serowoky, René Gronewold, J. Sherwood, H. Wang, Alexandra J Rafipay, Simón Méndez-Ferrer, Fraser L. Collins, Anke J. Roelofs, Chrysa Kapeni, J. Gage Crump, Christopher B. Little, Cosimo De Bari, Stephanie T Kuwahara, Francesca V. Mariani, M. Sambale, Joanna Smeeton, John F. Bateman
Publikováno v:
Annals of the Rheumatic Diseases
Ann Rheum Dis
Ann Rheum Dis
ObjectivesOsteophytes are highly prevalent in osteoarthritis (OA) and are associated with pain and functional disability. These pathological outgrowths of cartilage and bone typically form at the junction of articular cartilage, periosteum and synovi
Autor:
Shelby C. Martin, Robert D. Ladner, Stephanie T. Kuwahara, Peter M. Wilson, Anthony B. El-Khoueiry, Heinz-Josef Lenz, Melissa J. LaBonte
Publikováno v:
Investigational new drugs. 31(4)
Despite compelling preclinical data in colorectal cancer (CRC), the efficacy of HDACIs has been disappointing in the clinic. The goal of this study was to evaluate the effectiveness of vorinostat and panobinostat in a dose- and exposure-dependent man