Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stephanie Schoeffmann"'
Autor:
Susanne Kratzat, Viktoriya Nikolova, Cornelius Miething, Alexander Hoellein, Stephanie Schoeffmann, Oliver Gorka, Elke Pietschmann, Anna-Lena Illert, Jürgen Ruland, Christian Peschel, Jonas Nilsson, Justus Duyster, Ulrich Keller
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37433 (2012)
The Cks1 component of the SCF(Skp2) complex is necessary for p27(Kip1) ubiquitylation and degradation. Cks1 expression is elevated in various B cell malignancies including Burkitt lymphoma and multiple myeloma. We have previously shown that loss of C
Externí odkaz:
https://doaj.org/article/afe355765585493f97bae702598c6107
Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck
Autor:
Ulrich Keller, Guido Piontek, Anja Pickhard, Christian Peschel, Henning Bier, Tobias Dechow, Fabienne von Keitz, Stefan Wagenpfeil, Alexander Hoellein, Anja Baumgart, Martina Rudelius, Stephanie Schoeffmann
Publikováno v:
Oncotarget
Alexander Hoellein 1 , Anja Pickhard 2 , Fabienne von Keitz 1 , Stephanie Schoeffmann 1 , Guido Piontek 2 , Martina Rudelius 3 , Anja Baumgart 1 , Stefan Wagenpfeil 4 , Christian Peschel 1 , Tobias Dechow 1 , Henning Bier 2 and Ulrich Keller 1 1 III.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189365f8ce82b57dd9a8bca874db0636
https://doi.org/10.18632/oncotarget.311
https://doi.org/10.18632/oncotarget.311
Autor:
Christian Peschel, Stephanie Schoeffmann, Ulrich Platz, Florian Bassermann, Steffi Graf, Gabriele Hölzlwimmer, Monika Kröger, Robert A.J. Oostendorp, Ulrich Keller, Alexander Hoellein, Leticia Quintanilla-Fend
Publikováno v:
Molecular and Cellular Biology. 32:2416-2427
Cks1 is an activator of the SCF(Skp2) ubiquitin ligase complex that targets the cell cycle inhibitor p27(Kip1) for degradation. The loss of Cks1 results in p27(Kip1) accumulation and decreased proliferation and inhibits tumorigenesis. We identify her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77757c47747c9bc3e4135b0b2668287c
https://doi.org/10.1128/mcb.06771-11
https://doi.org/10.1128/mcb.06771-11
Autor:
Graham L. Collingridge, Viktor Lakics, Tammy M. K. Cheng, Stephen M. Fitzjohn, John L. Sherwood, Nadia Malik, Sabine Bahn, Hassan Rahmoune, Thomas M. Sanderson, Mark D. Tricklebank, Elaine Holmes, Emanuele Sher, Tsz M. Tsang, Michael J. O'Neill, Stephanie Schoeffmann, Eva Hradetzky, Laura W. Harris, Paul C. Guest
Publikováno v:
Neuropsychopharmacology
Neuropsychopharmacology, Nature Publishing Group, 2011, ⟨10.1038/npp.2011.219⟩
Neuropsychopharmacology, 37(2), 364-377. Nature Publishing Group
Neuropsychopharmacology, Nature Publishing Group, 2011, ⟨10.1038/npp.2011.219⟩
Neuropsychopharmacology, 37(2), 364-377. Nature Publishing Group
Administration of the DNA-alkylating agent methylazoxymethanol acetate (MAM) on embryonic day 17 (E17) produces behavioral and anatomical brain abnormalities, which model some aspects of schizophrenia. This has lead to the premise that MAM rats are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac99e5aeede91a0360eed93dcf664a55
https://doi.org/10.1038/npp.2011.219
https://doi.org/10.1038/npp.2011.219
Autor:
Hassan Rahmoune, Paul C. Guest, Hermelindis Ruh, Dagmar Koethe, Emanuel Schwarz, Markus Leweke, Yishai Levin, Laura Kranaster, Torsten Schoenborn, Marlis Herberth, Natalia D. Krzyszton, Stephanie Schoeffmann, Sabine Bahn
Publikováno v:
PROTEOMICS. 11:94-105
Little is known about the molecular factors that are altered in remitting bipolar disorder (BD) patients. We carried out proteome profiling of peripheral blood mononuclear cells (PBMCs) and serum from BD patients who were not experiencing mania or ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e2eabcde712808378a30bc1d415578
https://doi.org/10.1002/pmic.201000291
https://doi.org/10.1002/pmic.201000291
Autor:
Stephanie Schoeffmann, Stefanie M. Hauck, Cornelia A. Deeg, Johanna K. Zipplies, Barbara Amann, Manfred Stangassinger, Marius Ueffing
Publikováno v:
Journal of Proteome Research. 8:992-998
Identification of biomarkers is of critical relevance toward improving diagnosis and therapy of autoimmune disorders. Serum markers are a desirable choice as sera are easily accessible and the development of assays for routine clinical detection prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97331ad5cdb1eab107eb0f285fe1e992
https://doi.org/10.1021/pr800694y
https://doi.org/10.1021/pr800694y
Autor:
Stephanie Schoeffmann, Karsten Boldt, Stefanie M. Hauck, Per Ekström, Christian Johannes Gloeckner, Margaret E. Harley, Marius Ueffing
Publikováno v:
Mol. Cell. Proteomics 7, 1349-1361 (2008)
Glial cells support neuronal survival and function by secreting neurotrophic cytokines. Retinal Mueller glial cells (RMGs) support retinal neurons, especially photoreceptors. These highly light-sensitive sensory neurons receive vision, and their deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74533e9b86544713f99e2d3c7642a5ff
https://doi.org/10.1074/mcp.m700456-mcp200
https://doi.org/10.1074/mcp.m700456-mcp200
Autor:
Manfred Stangassinger, Barbara Amann, Cornelia A. Deeg, Marius Ueffing, Stephanie Schoeffmann, Stefanie M. Hauck, Hartmut Gerhards
Publikováno v:
Journal of Proteome Research. 6:2121-2131
Spontaneous equine recurrent uveitis (ERU) is an incurable autoimmune disease affecting the eye. Although retinal-autoantigen specific T-helper 1 cells have been demonstrated to trigger disease progression and relapses, the molecular processes leadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cde41f9509479d7c34bb6e10e53163
https://doi.org/10.1021/pr060668y
https://doi.org/10.1021/pr060668y
Autor:
Johanna K. Zipplies, Barbara Amann, Manfred Stangassinger, Stefanie M. Hauck, Stephanie Schoeffmann, Marius Ueffing, Cornelia A. Deeg, Christiaan Hendrikus van der Meijden
Publikováno v:
Investigative ophthalmologyvisual science. 51(1)
Purpose Equine recurrent uveitis (ERU) is an incurable disease affecting the inner eye that leads to blindness, through activated T cells that pass the blood-retinal barrier and destroy the retina. Serum markers are a desirable choice for monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeaffda546aa88f83fd6dc0af20ff52
https://pubmed.ncbi.nlm.nih.gov/19696180
https://pubmed.ncbi.nlm.nih.gov/19696180
Autor:
Stephanie Schoeffmann, Marius Ueffing, Manfred Stangassinger, Barbara Amann, Cornelia A. Deeg, Stefanie M. Hauck, Frank Altmann
Publikováno v:
Proteomics. 7(9)
Spontaneous equine recurrent uveitis (ERU) is an incurable autoimmune disease affecting the eye. Identifying biological markers or pathways associated with this disease may allow the understanding of its pathogenesis at a molecular level. The vitreou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1f2aae1bf31757725c8e0f7dc02c8a
https://pubmed.ncbi.nlm.nih.gov/17407186
https://pubmed.ncbi.nlm.nih.gov/17407186