Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Stephanie Schaefer‐Ramadan"'
Publikováno v:
Cancer Medicine, Vol 11, Iss 24, Pp 4989-5000 (2022)
Abstract Objective Identify protein contact points between TP53 and minichromosome maintenance (MCM) complex proteins 2, 3, and 5 with high resolution allowing for potential novel Cancer drug design. Methods A next‐generation sequencing‐based pro
Externí odkaz:
https://doaj.org/article/69f95f3c68ac4658906a7c14111c84e8
Autor:
Nayra M. Al-Thani, Stephanie Schaefer-Ramadan, Jovana Aleksic, Yasmin A. Mohamoud, Joel A. Malek
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Colon cancer is often driven by mutations of the adenomatous polyposis coli (APC) gene, an essential tumor suppressor gene of the Wnt β-catenin signaling pathway. APC and its cytoplasmic interactions have been well studied. Howev
Externí odkaz:
https://doaj.org/article/db27634126fd4368a237a3bbedfe4ccf
Autor:
Frank Schmidt, Houari B. Abdesselem, Karsten Suhre, Nishant N. Vaikath, Muhammad U. Sohail, Maryam Al-Nesf, Ilham Bensmail, Fathima Mashod, Hina Sarwath, Joerg Bernhardt, Stephanie Schaefer-Ramadan, Ti-Myen Tan, Priscilla E. Morris, Edward J. Schenck, David Price, Vidya Mohamed-Ali, Mohammed Al-Maadheed, Abdelilah Arredouani, Julie Decock, Jonathan M. Blackburn, Augustine M. K. Choi, Omar M. El-Agnaf
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background: Coronavirus disease (COVID-19) manifests many clinical symptoms, including an exacerbated immune response and cytokine storm. Autoantibodies in COVID-19 may have severe prodromal effects that are poorly understood. The interaction between
Externí odkaz:
https://doaj.org/article/cafc2cc0758a400281587d6a1c37112f
Autor:
Joel A. Malek, Jovana Aleksic, Nayra M Al-Thani, Stephanie Schaefer-Ramadan, David E. Hill, Yasmin A. Mohamoud
Publikováno v:
Proteins. 90(4)
Protein-protein interactions (PPIs) are essential in understanding numerous aspects of protein function. Here, we significantly scaled and modified analyses of the recently developed all-vs-all sequencing (AVA-Seq) approach using a gold-standard huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be3ed517e197f2c0e9789339030cf16
https://pubmed.ncbi.nlm.nih.gov/34850971
https://pubmed.ncbi.nlm.nih.gov/34850971
Autor:
null Stephanie Schaefer‐Ramadan, null Jovana Aleksic, null Nayra M. Al‐Thani, null Yasmin A. Mohamoud, null David E. Hill, null Joel A. Malek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89ae733146873ebb321a7c19be2d830
https://doi.org/10.1002/prot.26288/v2/response1
https://doi.org/10.1002/prot.26288/v2/response1
Autor:
Farid Ghelichkhani, Fabio A. Gonzalez, Mariia A. Kapitonova, Stephanie Schaefer-Ramadan, Jun Liu, Rujin Cheng, Sharon Rozovsky
Publikováno v:
Archives of Biochemistry and Biophysics. 731:109427
Selenoprotein S (selenos) is a small, intrinsically disordered membrane protein that is associated with various cellular functions, such as inflammatory processes, cellular stress response, protein quality control, and signaling pathways. It is prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38be410f7a90a492ffea3551ca57cfc9
https://doi.org/10.1016/j.abb.2022.109427
https://doi.org/10.1016/j.abb.2022.109427
Autor:
Simeon S. Andrews, Ikhlak Ahmed, Stephanie Schaefer-Ramadan, Joel A. Malek, Yasmin A. Mohamoud, Nayra M Al-Thani
Publikováno v:
Journal of Biological Chemistry. 294:11549-11558
Two-hybrid systems can be used for investigating protein-protein interactions and may provide important information about gene products with unknown function. Despite their success in mapping protein interactions, two-hybrid systems have remained mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f69b2983b6679481246476e6e9af4f40
https://doi.org/10.1074/jbc.ra119.008792
https://doi.org/10.1074/jbc.ra119.008792
Autor:
Mohammed Al-Hashimi, Maciej Barłóg, Hassan S. Bazzi, Jim D. Roach, Khaled Machaca, Stephanie Schaefer-Ramadan
Publikováno v:
Bioorganic Chemistry. 87:366-372
TPEN is an amino chelator of transition metals that is effective at the cellular and whole organism levels. Although TPEN of often used as a selective zinc chelators, it has affinity for copper and iron and has been shown to chelate both biologically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5dbe74d4d73b8708865d41350079c7
https://doi.org/10.1016/j.bioorg.2019.03.045
https://doi.org/10.1016/j.bioorg.2019.03.045
Publikováno v:
Journal of Cellular Physiology. 233:3164-3175
The G2-M transition of the cell cycle requires the activation of members of the Cdc25 dual specificity phosphatase family. Using Xenopus oocyte maturation as a model system, we have previously shown that chelation of transition metals blocks meiosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b127fe488fbc22f81eec1defdd633eca
https://doi.org/10.1002/jcp.26157
https://doi.org/10.1002/jcp.26157
Autor:
Khaled Machaca, Abdulrahman Al-Abdulmalek, Ghizlaine Bendriss, Stephanie Schaefer-Ramadan, Satanay Hubrack
Publikováno v:
Protein Expression and Purification. 120:148-152
The Cdc25 family encodes dual specificity protein phosphatases that play critical roles in cell cycle progression. Activation of the Cdc25C represents a primary driver for meiosis progression in Xenopus oocytes. Given its central role in meiosis the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188c56aa3c9d05d17fc2f9b0ef9a75c4
https://doi.org/10.1016/j.pep.2015.12.007
https://doi.org/10.1016/j.pep.2015.12.007