Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stephanie Santarriaga"'
Publikováno v:
mSphere, Vol 4, Iss 3 (2019)
ABSTRACT The social amoeba Dictyostelium discoideum’s proteome contains a vast array of simple sequence repeats, providing a unique model to investigate proteostasis. Upon conditions of cellular stress, D. discoideum undergoes a developmental proce
Externí odkaz:
https://doaj.org/article/a268bffb7a28466b97980479c8970da0
Motor Neuron Generation from iPSCs from Identical Twins Discordant for Amyotrophic Lateral Sclerosis
Autor:
Emily R. Seminary, Stephanie Santarriaga, Lynn Wheeler, Marie Mejaki, Jenica Abrudan, Wendy Demos, Michael T. Zimmermann, Raul A. Urrutia, Dominic Fee, Paul E. Barkhaus, Allison D. Ebert
Publikováno v:
Cells, Vol 9, Iss 3, p 571 (2020)
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder characterized by the loss of the upper and lower motor neurons. Approximately 10% of cases are caused by specific mutations in known genes, with the remaining cases having no
Externí odkaz:
https://doaj.org/article/093317604a7548b89da66bc393e6a3f4
Autor:
Howard J. Jacob, James D. Shull, Michael B. Dwinell, Peter S. LaViolette, Paula E. North, Jozef Lazar, Zelmira Lazarova, Scott C. Fahrenkrug, Wenfang Tan, Daniel F. Carlson, Jeffery De Pons, Shirng-Wern Tsaih, Sophia Ran, Carol Moreno, Aron M. Geurts, Angela Lemke, Ishan Roy, Stephanie Santarriaga, Allison B. Sarkis, Nathan Rudemiller, Bradley T. Endres, Michael J. Flister
The majority of causative variants in familial breast cancer remain unknown. Of the known risk variants, most are tumor cell autonomous, and little attention has been paid yet to germline variants that may affect the tumor microenvironment. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e0154732934a5924ba7a91c179c2905
https://doi.org/10.1158/0008-5472.c.6505833
https://doi.org/10.1158/0008-5472.c.6505833
Autor:
Howard J. Jacob, James D. Shull, Michael B. Dwinell, Peter S. LaViolette, Paula E. North, Jozef Lazar, Zelmira Lazarova, Scott C. Fahrenkrug, Wenfang Tan, Daniel F. Carlson, Jeffery De Pons, Shirng-Wern Tsaih, Sophia Ran, Carol Moreno, Aron M. Geurts, Angela Lemke, Ishan Roy, Stephanie Santarriaga, Allison B. Sarkis, Nathan Rudemiller, Bradley T. Endres, Michael J. Flister
Expanded Materials and Methods, Supplemental Figures, and Supplemental Tables Figure S1. Flow cytometric analysis of peripheral blood from SS, SS.BN3, SSIL2Rγ, and SS.BN3IL2Rγ rats. Figure S2.SH2B3 specifically marks CD31+ blood vessels, but not LY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c154ffd6a88cb5cd68a80a135811e4
https://doi.org/10.1158/0008-5472.22401336
https://doi.org/10.1158/0008-5472.22401336
Publikováno v:
Schizophrenia Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::960484428a5a01255e96a9b516a131c4
https://doi.org/10.1016/j.schres.2023.02.029
https://doi.org/10.1016/j.schres.2023.02.029
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2429
Protein aggregation is one of the hallmarks of many neurodegenerative diseases. While protein aggregation is a heavily studied aspect of neurodegenerative disease, methods of detection vary from one model system to another. Induced pluripotent stem c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0eb319bb6c538b7674318a92c40dcd4f
https://pubmed.ncbi.nlm.nih.gov/35507156
https://pubmed.ncbi.nlm.nih.gov/35507156
In schizophrenia and bipolar disorder, tight junction deficits in brain microvascular endothelial cells (BMECs) lead to blood brain barrier (BBB) dysfunction. Using an in vitro model of human BBB function, we show that BMECs derived from human induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::562b9cf861353158e5b8937212bf8e60
https://doi.org/10.21203/rs.3.rs-1162029/v1
https://doi.org/10.21203/rs.3.rs-1162029/v1
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619780
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84ea71ff45c8fd2c3ab3a9b24f00cef5
https://doi.org/10.1007/978-1-0716-1979-7_6
https://doi.org/10.1007/978-1-0716-1979-7_6
Protein misfolding and aggregation are shared features of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), and protein quality control disruption contributes to neuronal toxicity. Therefore, reducing protein aggregation coul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad93bbea75b7664312dab3d36857220a
https://doi.org/10.1101/2020.12.21.423691
https://doi.org/10.1101/2020.12.21.423691
Publikováno v:
mSphere, Vol 4, Iss 3, p e00314-19 (2019)
mSphere
mSphere, Vol 4, Iss 3 (2019)
mSphere
mSphere, Vol 4, Iss 3 (2019)
During cellular stress, many microbes undergo a transition to a dormant state. This includes the social amoeba Dictyostelium discoideum that transitions from a unicellular amoeba to a multicellular fruiting body upon starvation. In this work, we iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc62925140d8ca0aa48a7fd833dceafb
https://doaj.org/article/8fe7fb4627234913a5eaa26972ecfaa8
https://doaj.org/article/8fe7fb4627234913a5eaa26972ecfaa8