Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stephanie S Cush"'
Autor:
Stephanie S Cush, Glennys V Reynoso, Olena Kamenyeva, Jack R Bennink, Jonathan W Yewdell, Heather D Hickman
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005493 (2016)
Skin infection with the poxvirus vaccinia (VV) elicits a powerful, inflammatory cellular response that clears virus infection in a coordinated, spatially organized manner. Given the high concentration of pro-inflammatory effectors at areas of viral i
Externí odkaz:
https://doaj.org/article/c142891839534da5bbde6d2ae883f015
Autor:
Stephanie S. Cush, Joseph P. Menetski, Paul L. Herrling, John A. Wagner, Christopher P. Austin, Steven C. Hoffmann, Tania Nayak Kamphaus
Publikováno v:
Clinical Pharmacology and Therapeutics
The Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium (BC) is a public-private partnership that aims to facilitate drug development with biomarkers across a range of therapeutic areas. The BC is organized to address specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa8de98557300c495e797b6a43e1145
http://europepmc.org/articles/PMC6593617
http://europepmc.org/articles/PMC6593617
Autor:
Emilio Flaño, Stephanie S. Cush
Publikováno v:
The Journal of Immunology. 186:4051-4058
Functional CD8 T cell effector and memory responses are generated and maintained during murine γ-herpesvirus 68 (γHV68) persistent infection despite continuous presentation of viral lytic Ags. However, the identity of the CD8 T cell subpopulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74aa5c8e1f95c2998154420a34e7e0c8
https://doi.org/10.4049/jimmunol.1003122
https://doi.org/10.4049/jimmunol.1003122
Autor:
Stephanie S. Cush, David H. Ravneberg, Janet L. Weslow-Schmidt, Emilio Flaño, Kathleen M. Anderson
Publikováno v:
The Journal of Immunology. 179:141-153
During infection with viruses that establish latency, the immune system needs to maintain lifelong control of the infectious agent in the presence of persistent Ag. By using a γ-herpesvirus (γHV) infection model, we demonstrate that a small number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98a134879a73ca00751a786a009f95da
https://doi.org/10.4049/jimmunol.179.1.141
https://doi.org/10.4049/jimmunol.179.1.141
Autor:
Marie-Dominique Fillipi, Brenna Carey, Joe Kitzmiller, Nicholas S. Geraci, Kara Wernke-Dollries, Michael O'Connor, Terry Richardson, Pierre-Yves Berclaz, Bruce C. Trapnell, Christina Hermoyian, Jeffrey A. Whitsett, Thomas R. Korfhagen, Stephanie S. Cush
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 36:114-121
Alveolar macrophages (AMs) normally respond to lipopolysaccharide (LPS) by activating Toll-like receptor (TLR)-4 signaling, a mechanism critical to lung host defense against gram-negative bacteria such as Pseudomonas aeruginosa. Because granulocyte m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed1e1707ec102dd0bb156347788e2ae
https://doi.org/10.1165/rcmb.2006-0174oc
https://doi.org/10.1165/rcmb.2006-0174oc
Autor:
Jiajie Wei, James S. Gibbs, Heather D. Hickman, Stephanie S. Cush, Jonathan W. Yewdell, Jack R. Bennink
Publikováno v:
The Journal of biological chemistry. 290(26)
Green fluorescent protein (GFP) and other fluorescent proteins are essential tools for biological research. When fused to peptides or proteins as a reporter, GFP enables localization and quantitation of gene products in otherwise unmanipulated live c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812d033885e2dc071c6fa7e5ca554cb3
https://pubmed.ncbi.nlm.nih.gov/25971973
https://pubmed.ncbi.nlm.nih.gov/25971973
Autor:
Jack R. Bennink, Jonathan W. Yewdell, Heather D. Hickman, Stephanie S. Cush, Barbara F. Ngudiankama, James S. Gibbs, Glennys V. Reynoso
Publikováno v:
Immunity. 42(3)
CD8(+) T cells play a critical role in limiting peripheral virus replication, yet how they locate virus-infected cells within tissues is unknown. Here, we have examined the environmental signals that CD8(+) T cells use to localize and eliminate virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e149f3394ea0042095422af7cbfb8cb
https://pubmed.ncbi.nlm.nih.gov/25786170
https://pubmed.ncbi.nlm.nih.gov/25786170
Autor:
Kathleen A. Stuller, Marcia A. Blackman, Fang Ye, Emilio Flaño, Janet L. Weslow-Schmidt, Stephanie S. Cush
It is still unknown whether a noninfectious gammaherpesvirus vaccine is able to prevent or reduce virus persistence. This led us to use dendritic cells loaded with tumor B cells as a vaccine approach for the murine gammaherpesvirus 68 (γHV68) model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07b8e35b277a8ca18ad490429094634
https://europepmc.org/articles/PMC2918994/
https://europepmc.org/articles/PMC2918994/
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(7)
The direct effector mechanisms of CD4 T cells during γ-herpesvirus 68 (γHV68)-persistent infection are less well understood than those of their CD8 T cell counterparts, although there is substantial evidence that CD4 T cells are critical for the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec77ddc10e165e133f2f3ad74a163cab
https://pubmed.ncbi.nlm.nih.gov/20208003
https://pubmed.ncbi.nlm.nih.gov/20208003
Autor:
Stephanie S. Cush, Emilio Flaño
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(7)
Ag persistence during high-titer chronic viral infections induces CD8 T cell dysfunction and lack of Ag-independent CD8 T cell memory formation. However, we have a poor understanding of the generation and maintenance of CD8 T cell memory during asymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f33896338ca749145d114c5730850d6
https://pubmed.ncbi.nlm.nih.gov/19299697
https://pubmed.ncbi.nlm.nih.gov/19299697