Genotype-driven pharmacokinetic simulations of warfarin levels in Puerto Ricans

Autor: Camila de las Barreras, Vilmali Lopez Mejias, Victor Mangas, Leyanis Rodríguez-Vera, Gledys Reynaldo, Cornelis P. Vlaar, Jean-Christophe Monbaliu, Torsten Stelzer, Jorge Duconge, Stephanie Reyes-González

Publikováno v: Drug Metab Pers Ther
Reyes-González, Stephanie Barreras, Camila de las Reynaldo, Gledys Rodríguez-Vera, Leyanis Vlaar, Cornelis Lopez Mejias, Vilmali Monbaliu, Jean-Christophe M. Stelzer, Torsten Mangas Sanjuan, Victor Duconge,Jorge 2020 Genotype-driven pharmacokinetic simulations of warfarin levels in Puerto Ricans Drug Metabolism and Personalized Therapy 1 7
RODERIC: Repositorio Institucional de la Universitat de Valéncia
instname
RODERIC. Repositorio Institucional de la Universitat de Valéncia

Objectives The inter-individual variability of warfarin dosing has been linked to genetic polymorphisms. This study was aimed at performing genotype-driven pharmacokinetic (PK) simulations to predict warfarin levels in Puerto Ricans. Methods Analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999afa895e50b60db8b21b973c3d6494
https://pubmed.ncbi.nlm.nih.gov/32809952