Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stephanie Rainwater"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 30-38 (2021)
Efficient delivery of nucleic acids for the engineering of primary T cells is central to the study of the basic biology of these key immune effector cells and has clinical implications. To date, lentiviral vectors delivering guide RNAs for CRISPR-Cas
Externí odkaz:
https://doaj.org/article/0633a04dc9214277b9f0c2aa3455c1f8
Autor:
Katherine L. Williams, Bingjie Wang, Dana Arenz, James A. Williams, Adam S. Dingens, Valerie Cortez, Cassandra A. Simonich, Stephanie Rainwater, Dara A. Lehman, Kelly K. Lee, Julie Overbaugh
Publikováno v:
Cell Reports, Vol 23, Iss 3, Pp 682-691 (2018)
Summary: Eliciting broad and potent HIV-specific neutralizing antibody responses represents the holy grail of HIV vaccine efforts. Data from singly infected individuals with broad and potent plasma neutralizing activity targeting one epitope have gui
Externí odkaz:
https://doaj.org/article/d2f932fc2bb3434597cf2cf86c15ef2e
Autor:
Katherine L. Williams, Valerie Cortez, Adam S. Dingens, Johannes S. Gach, Stephanie Rainwater, Julie F. Weis, Xuemin Chen, Paul Spearman, Donald N. Forthal, Julie Overbaugh
Publikováno v:
EBioMedicine, Vol 2, Iss 10, Pp 1464-1477 (2015)
HIV-specific antibodies (Abs) can reduce viral burden by blocking new rounds of infection or by destroying infected cells via activation of effector cells through Fc–FcR interaction. This latter process, referred to as antibody-dependent cellular c
Externí odkaz:
https://doaj.org/article/6174c86b170e432ebd34d500fcb54b17
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 30-38 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Efficient delivery of nucleic acids for the engineering of primary T cells is central to the study of the basic biology of these key immune effector cells and has clinical implications. To date, lentiviral vectors delivering guide RNAs for CRISPR-Cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd85dada74568bf79f26a15152cfa474
http://www.sciencedirect.com/science/article/pii/S2329050120302242
http://www.sciencedirect.com/science/article/pii/S2329050120302242
Publikováno v:
Virology. 398:115-124
The origin of broadly neutralizing HIV-specific antibodies and their relation to HIV evolution are not well defined. Here we examined virus evolution and neutralizing antibody escape in a subtype A infected individual with a broad, cross subtype, ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fec914b6000cf81b292342ff69cd38
https://doi.org/10.1016/j.virol.2009.11.032
https://doi.org/10.1016/j.virol.2009.11.032
Autor:
Zahra Jalalian-Lechak, Minh An Nguyen, Ozge C. Dogan, Catherine A. Blish, Julie Overbaugh, Stephanie Rainwater
Publikováno v:
Journal of Virology. 83:7783-7788
The human immunodeficiency virus type 1 (HIV-1) variants that are transmitted to newly infected individuals are the primary targets of interventions, such as vaccines and microbicides, aimed at preventing new infections. Newly acquired subtype A, B,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f77cc23e5ff1b04ce45defffd2e660
https://doi.org/10.1128/jvi.00673-09
https://doi.org/10.1128/jvi.00673-09
Autor:
Shannon DeVange, Joan K. Kreiss, Julie Overbaugh, Stephanie Rainwater, Manish Sagar, Kishorchandra Mandaliya, Jeckoniah O. Ndinya-Achola
Publikováno v:
AIDS Research and Human Retroviruses. 21:1060-1065
There are multiple subtypes of HIV-1 circulating worldwide, but recently, subtype C has become highly prevalent, particularly in certain geographic regions. It is unclear whether the dominance of subtype C or other subtypes is due to increased fitnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f17e83ff6531d59ee6758216cbaf6f
https://doi.org/10.1089/aid.2005.21.1060
https://doi.org/10.1089/aid.2005.21.1060
Publikováno v:
Journal of Virology. 79:10701-10708
A major premise underlying current human immunodeficiency virus type 1 (HIV-1) vaccine approaches is that preexisting HIV-1-specific immunity will block or reduce infection. However, the recent identification of several cases of HIV-1 reinfection sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a4daf04129fb8a30100f3c86a1bec6
https://doi.org/10.1128/jvi.79.16.10701-10708.2005
https://doi.org/10.1128/jvi.79.16.10701-10708.2005
Autor:
Dorothy Mbori-Ngacha, Stephanie Rainwater, Julie Overbaugh, Ruth Nduati, Dana Panteleeff, Grace John-Stewart, Barbra A. Richardson, Christine M. Rousseau
Publikováno v:
The Journal of Infectious Diseases. 192:492-496
HIV-1 is divided into types and subtypes on the basis of sequence relatedness, and typically only small regions of the viral genome are compared. There are conflicting data on the role played by HIV-1 subtype in HIV-1 disease progression [1, 2]. Ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42efb9794eed0a2d3df6283975210221
https://doi.org/10.1086/431514
https://doi.org/10.1086/431514
Autor:
Stephanie Rainwater, E. Michelle Long, Ludo Lavreys, Kishorchandra Mandaliya, Julie Overbaugh
Publikováno v:
AIDS Research and Human Retroviruses. 18:567-576
Although nearly half of the HIV-1-infected adults in the world are women, little is known about the virologic determinants of transmission to women. Studies suggest that women are frequently infected with multiple HIV-1 genotypes, whereas men are inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c02c519094911160c83661ca9b826d9
https://doi.org/10.1089/088922202753747914
https://doi.org/10.1089/088922202753747914