Výsledky vyhledávání - "Stephanie R. Lochhead"

Paradoxical Response to Prophylactic Didox (N-3, 4 Trihydroxybenzamide) Treatment in Murine Cytomegalovirus-Infected Mice

Autor: Yajarayma J. Tang-Feldman, G. Raymond Lochhead, Claire Pomeroy, Stephanie R. Lochhead, Mohammed S. Inayat, Vera S Go, Cindy Yu, Oliver R. Oakley, Howard L. Elford

Publikováno v: Antiviral Therapy. 16:1277-1286

Background In this study, we investigated the effect of Didox (DX) on the pathogenicity of and host responses to murine cytomegalovirus (MCMV) infection. Methods In vitro efficacy of DX against MCMV was determined using plaque reduction assays. For i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e961bfaf3076aba413aebbff9e85eea0
https://doi.org/10.3851/imp1893

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In vivo characterization of cytokine profiles and viral load during murine cytomegalovirus-induced acute myocarditis

Autor: Claire Pomeroy, Dipika Tuteja, Stephanie R. Lochhead, Yajarayma J. Tang-Feldman, Amanda Ashton-Sager, Jethro Trees Ritter, Marko Estrada, Cindy Yu, G. Raymond Lochhead, Christian M. Leutenegger

Publikováno v: Cardiovascular Pathology. 19:83-93

Murine cytomegalovirus (MCMV) is an etiologic agent of acute and chronic myocarditis in BALB/c mice. Immunologic host responses appear to play a key role in pathogenesis but have been incompletely defined.BALB/c mice were infected with a sublethal do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5db969a9265202f1194712b96f6d37
https://doi.org/10.1016/j.carpath.2008.12.001

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Murine Cytomegalovirus (MCMV) Infection Upregulates P38 MAP kinase in Aortas of Apo E KO Mice: a Molecular Mechanism for MCMV-Induced Acceleration of Atherosclerosis

Autor: Claire Pomeroy, Michael D. George, Cindy Yu, G. Raymond Lochhead, Amparo C Villablanca, Stephanie R. Lochhead, Yajarayma J. Tang-Feldman

Multiple studies suggest an association between cytomegalovirus (CMV) infection and atherogenesis; however, the molecular mechanisms by which viral infection might exacerbate atherosclerosis are not well understood. Aortas of MCMV-infected and uninfe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44079a224eb5fbd79efdd9944888f280
https://europepmc.org/articles/PMC4591060/

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Autor: Adria Honda, Magnolia Bostick, Judy Callis, Stephanie R. Lochhead, Scott Palmer

Related to Ubiquitin (RUB)/Nedd8 is a ubiquitin-like protein that covalently attaches to cullins, a subunit of the SCF (for Skp, Cdc53p/Cul1, and F-box protein) complex, an E3 ubiquitin ligase, and has been shown to be required for robust function of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cd99d0bcaec22616c95af69f74de12
https://europepmc.org/articles/PMC520943/

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Interleukin-10 repletion suppresses pro-inflammatory cytokines and decreases liver pathology without altering viral replication in murine cytomegalovirus (MCMV)-infected IL-10 knockout mice

Autor: Stephanie R. Lochhead, Yajarayma J. Tang-Feldman, Cindy Yu, Claire Pomeroy, G. Raymond Lochhead

Publikováno v: Inflammation Research

Objective and design To determine the role of interleukin-10 (IL-10) in protecting against the deleterious pro-inflammatory cytokine response to murine cytomegalovirus (MCMV), we studied the impact of IL-10 repletion in MCMV-infected IL-10 knockout (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e39e59edc7dc602c247571385b6dfb0

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