Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stephanie R. Edmondson"'
Autor:
Arthur S Waldbaum, Jane R Schwebke, Jeremy R A Paull, Clare F Price, Stephanie R Edmondson, Alex Castellarnau, Philip McCloud, George R Kinghorn
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232394 (2020)
BackgroundAstodrimer Gel contains a novel dendrimer intended to treat and prevent bacterial vaginosis. We assessed the efficacy and safety of Astodrimer Gel for treatment of bacterial vaginosis.Methods132 women with bacterial vaginosis were randomize
Externí odkaz:
https://doaj.org/article/4438991f574f452e952875afb63461b9
Autor:
Christopher J. Wraight, George A. Werther, Susan P. Thumiger, Timothy E. Adams, Stephanie R. Edmondson
Publikováno v:
Growth Factors. 23:151-159
The insulin-like growth factor receptor (IGF-IR) is critical in epidermal development and IGF binding protein-3 (IGFBP-3), a modulator of cellular activity with or without IGF-dependence, co-localises with epidermal IGF-IRs. We have investigated whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961ab3a64489b183fc42fcaee927f91f
https://doi.org/10.1080/08977190500153680
https://doi.org/10.1080/08977190500153680
Publikováno v:
Endocrine Reviews. 24:737-764
GH and IGF-I and -II were first identified by their endocrine activity. Specifically, IGF-I was found to mediate the linear growth-promoting actions of GH. It is now evident that these two growth factor systems also exert widespread activity througho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba40c38d86369b7669a219b469105ae
https://doi.org/10.1210/er.2002-0021
https://doi.org/10.1210/er.2002-0021
Publikováno v:
Journal of Investigative Dermatology. 116:491-497
The insulin-like growth factor (IGF) system is essential for epidermal homeostasis. Insulin-like growth factor binding protein 3 (IGFBP-3), a modulator of IGF action that also exhibits IGF-independent activity, is localized to selected keratinocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133b15e363f54b5cc4968a8a039fe006
https://doi.org/10.1046/j.0022-202x.2001.temp.doc.x
https://doi.org/10.1046/j.0022-202x.2001.temp.doc.x
Autor:
Paul J. White, Stephanie R. Edmondson, Christopher J. Wraight, Sandra C. McKean, Daryl J. Venables, Ingrid J. Liepe, George A. Werther, Rhys Fogarty
Publikováno v:
Nature Biotechnology. 18:521-526
Epidermal hyperplasia is a key feature of the common skin disorder psoriasis. Stimulation of epidermal keratinocytes by insulin-like growth factor I (IGF-I) is essential for cell division, and increased sensitivity to IGF-I may occur in psoriasis. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7dddb4b936915483d3adc736edc8d16
https://doi.org/10.1038/75382
https://doi.org/10.1038/75382
Autor:
George A. Werther, Andrew C. McFarlane, Stephanie R. Edmondson, Vincenzo C. Russo, Christopher J. Wraight
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 84:1638-1644
Melanocytes, highly differentiated neural crest-derived cells, are located in the basal layer of the epidermis, where they play a role in protecting against UV damage in the skin. Previous studies suggest that both growth hormone (GH) and the insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dba279b01c64570d55bdb243b3b3fdf
https://doi.org/10.1210/jcem.84.5.5692
https://doi.org/10.1210/jcem.84.5.5692
Autor:
Vincenzo C. Russo, Stephanie R. Edmondson, George A. Werther, Christopher J. Wraight, Mari Murashita
Publikováno v:
Journal of Cellular Physiology. 179:201-207
Insulin-like growth factor-I (IGF-I) is essential for normal epidermal homeostasis; however, the role of IGF binding proteins (IGFBPs), regulators of IGF action, remains unclear. Here we examine the regulation of human keratinocyte-produced IGFBPs by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfea4dcc9f2f0a6c470a75d167e7d0a8
https://doi.org/10.1002/(sici)1097-4652(199905)179:2<201::aid-jcp10>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199905)179:2<201::aid-jcp10>3.0.co
Autor:
Leon A. Bach, George Arthur Werther, Glynis J. Price, Stephanie R. Edmondson, Jennifer L. Berka
Publikováno v:
Kidney International. 48(2):402-411
Localization of mRNAs for insulin-like growth factor binding proteins 1 to 6 in rat kidney. Insulin-like growth factor-I (IGF-I) is a peptide growth factor whose activity is modulated by interaction with the family of six IGF binding proteins (IGFBPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da08d90c07c5c03e780c88540ca91ff
Autor:
George A. Werther, Vincenzo C. Russo, Christopher J. Wraight, Stephanie R. Edmondson, Mari M. Murashita
Publikováno v:
Journal of Cellular Physiology. 163:339-345
The role and mechanisms of action of insulin-like growth factors (IGFs) in skin remain unclear. Epidermal keratinocytes possess IGF-I receptors and are responsive to IGF-I, which is primarily derived from underlying dermal fibroblasts. IGF binding pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd2d9ae1b6e327172f501fc80188c32
https://doi.org/10.1002/jcp.1041630215
https://doi.org/10.1002/jcp.1041630215
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 79:1444-1449
The role of the insulin-like growth factors (IGFs) in human skin physiology has been increasingly recognized, although relatively little is known about the cell types involved or the cellular mechanisms that mediate these responses. Epidermal keratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f3120c81b31670d8474caf86033f76
https://doi.org/10.1210/jcem.79.5.7525637
https://doi.org/10.1210/jcem.79.5.7525637