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of 4
pro vyhledávání: '"Stephanie Perkail"'
Autor:
Anna Gams, Alejandro Nevarez, Stephanie Perkail, Aileen Venegas, Sharon A. George, Tatiana Efimova, Igor R. Efimov
Publikováno v:
Physiological Reports, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract Abnormal heart rate variability (HRV) is commonly observed in cancer patients who have undergone targeted therapy and/or surgery, yet the effects of cancer itself on cardiac function remain underexplored. Specifically, there is limited knowl
Externí odkaz:
https://doaj.org/article/64547d8cd16c4133ae398ea5eda71d25
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Chronic pancreatitis is linked with an increased risk of pancreatic cancer. Here the authors show that genomic instability due to the loss of BRCA1 associated protein-1, frequently observed in patients with pancreatic cancer, is associated with chron
Externí odkaz:
https://doaj.org/article/a67a5dd4c14849d2a389e9a68040dda2
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Chronic pancreatitis represents a risk factor for the development of pancreatic cancer. We find that heterozygous loss of histone H2A lysine 119 deubiquitinase BAP1 (BRCA1 Associated Protein-1) associates with a history of chronic pancreatitis and oc
Autor:
Nicole Casasanta, Stephanie Perkail, Jaclyn Andricovich, Alexandros Tzatsos, Weiqun Peng, Yan Kai
Publikováno v:
Cancer cell. 33(3)
Summary KDM6A, an X chromosome-encoded histone demethylase and member of the COMPASS-like complex, is frequently mutated in a broad spectrum of malignancies and contributes to oncogenesis with poorly characterized mechanisms. We found that KDM6A loss