Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Stephanie Patfield"'
Publikováno v:
Toxins, Vol 5, Iss 10, Pp 1845-1858 (2013)
Shiga toxin-producing Escherichia coli (STEC) food contaminations pose serious health concerns, and have been the subject of massive food recalls. STEC has been identified as the major cause of the life-threatening complication of hemolytic uremic sy
Externí odkaz:
https://doaj.org/article/01a26001600545d98e2188228844399f
Publikováno v:
mSphere, Vol 1, Iss 1 (2016)
ABSTRACT Shiga toxin (Stx) is a major virulence factor of several bacterial pathogens that cause potentially fatal illness, including Escherichia coli and Shigella spp. The continual emergence of new subtypes of Stxs presents challenges for the clini
Externí odkaz:
https://doaj.org/article/0b2e261d5f4442cd85123d59dad25783
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0148092 (2016)
Shiga toxin (Stx) is a common virulence factor of all Shiga toxin producing E. coli (STEC) that cause a wide spectrum of disease, including hemorrhagic colitis and hemolytic uremic syndrome (HUS). Although several commercial kits are available for de
Externí odkaz:
https://doaj.org/article/df1fce185f4544168c6288795b5da2a4
Autor:
Xiaohua He, Gianluigi Ardissino, Stephanie Patfield, Luisa W. Cheng, Christopher J. Silva, Maurizio Brigotti
Publikováno v:
Toxins, Vol 10, Iss 2, p 59 (2018)
Shiga toxins (Stx) released by Stx-producing E. coli (STEC) are virulence factors that are most closely 3associated with hemolytic uremic syndrome (HUS), a life-threatening complication of intestinal infections by STEC. Stx have to enter into the cir
Externí odkaz:
https://doaj.org/article/b0f68e80472c43ee841423c21ff8faca
Autor:
Xiaohua He, Stephanie Patfield, Luisa W. Cheng, Larry H. Stanker, Reuven Rasooly, Thomas A. McKeon, Yuzhu Zhang, David L. Brandon
Publikováno v:
Toxins, Vol 9, Iss 12, p 386 (2017)
Abrin, a member of the ribosome-inactivating protein family, is produced by the Abrus precatorius plant. Having the potential to pose a severe threat to both human and animal health, abrin is classified as a Select Agent by the U.S. Department of Hea
Externí odkaz:
https://doaj.org/article/70a0dfd02250443bb2306c61bff93ce1
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132419 (2015)
Stx2e is a primary virulence factor in STEC strains that cause edema disease in neonatal piglets. Though Stx2a and Stx2e are similar, many antibody-based Stx detection kits are designed to detect Stx2a and do not recognize the Stx2e subtype.Four mono
Externí odkaz:
https://doaj.org/article/2e83a58c83144c44862c6997aaf52305
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99854 (2014)
BACKGROUND: Shiga toxin-producing E. coli (STEC) are a group of common and potentially deadly intestinal pathogens expressing Shiga toxin (Stx) as a primary virulence factor. Of the two types of Stx, Stx2 is responsible for more severe symptoms durin
Externí odkaz:
https://doaj.org/article/c8f904dfc3bc4f3b9dc318218d9fb093
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76368 (2013)
BACKGROUND: Shiga toxin-producing Escherichia coli (STEC) are frequent causes of severe human diseases ranging from diarrhea to hemolytic uremic syndrome. The existing strategy for detection of STEC relies on the unique sorbitol-negative fermentation
Externí odkaz:
https://doaj.org/article/20c7b973117e49a1866787f546d71fd0
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76563 (2013)
BACKGROUND: Shiga toxin 2 (Stx2) is a major virulence factor in gastrointestinal diseases caused by Escherichia coli. Although Stx2a (prototypical Stx2) is well-studied, all seven subtypes of Stx2 have been associated with disease in mammals. Several
Externí odkaz:
https://doaj.org/article/84723aa675cc46ffbc62f5bab88b6275
Autor:
Alfredo Caprioli, Damiano Picicco, Domenica Carnicelli, Maurizio Brigotti, Sara Testa, Pier Luigi Tazzari, Francesca Ricci, Xiaohua He, Gaia Scavia, Fabio Paglialonga, Elisabetta Galassi, Stephanie Patfield, Elisa Porcellini, Gianluigi Ardissino, Stefano Morabito, Valentina Arfilli
Publikováno v:
Thrombosis and Haemostasis. 120:107-120
Hemolytic uremic syndrome (HUS), the leading cause of acute renal failure in children (< 3 years), is mainly related to Shiga toxins (Stx)-producing Escherichia coli (STEC) infections. STEC are confined to the gut resulting in hemorrhagic colitis, wh