Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stephanie Pascarella"'
Autor:
Ravit Geva, Antonio Jimeno, Khanh T. Do, S. Kummar, Manish R. Patel, Lisa M. Johansen, Stephanie Pascarella, Salomon M. Stemmer, Ruth Perets, Ding Wang, Patricia LoRusso, Sima Zacharek, Ryan J. Sullivan, Robert S. Meehan, Praveen Aanur, Sheryl Chen, Josh Frederick, Todd M. Bauer, Randy F. Sweis, Oleg Milberg, Shilpa Gupta, Andressa S. Laino, Patrick M. Reagan, William Randolph
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A569-A569
BackgroundmRNA-2752 is a novel mRNA-based therapeutic agent encoding OX40L T cell co-stimulator, IL-23 and IL-36γ pro-inflammatory cytokines. Preclinical data demonstrate synergy in combination with PD-L1 blockade.MethodsThis study evaluated the saf
Autor:
Stephanie Pascarella, Lisa M. Johansen, Kurt A. Schalper, Todd M. Bauer, Ding Wang, Joshua Frederick, Robert S. Meehan, William Randolph, Jing Sun, Shilpa Gupta, Honghong Zhou, Khanh T. Do, Deanna Teoh, Andressa S. Laino, Wallace Akerley, Pamela S. Cohen, Ryan J. Sullivan, Sima Zacharek, Antonio Jimeno
Publikováno v:
Cancer Research. 80:CT032-CT032
Background: While PD-1/L1 blockade is an effective therapeutic approach for many patients with solid and hematologic malignancies, it is not sufficient to induce tumor regressions in the majority of patients. Optimal T cell responses require T cell r
Publikováno v:
Viruses, Vol 1, Iss 2, Pp 126-143 (2009)
The persistent infection with hepatitis C virus is a major cause of chronic liver disease worldwide. However, the morbidity associated with hepatitis C virus widely varies and depends on several host-related cofactors, such as age, gender, alcohol co
Externí odkaz:
https://doaj.org/article/aefa8c9abbd64d849bad5f935e5f2db5
Autor:
Isabelle Morard, Sophie Clément, Alexandra Calmy, Alessandra Mangia, Andrea Cerny, Andrea De Gottardi, Meri Gorgievski, Markus Heim, Raffaele Malinverni, Darius Moradpour, Beat Müllhaupt, David Semela, Stéphanie Pascarella, Pierre-Yves Bochud, Franco Negro, Swiss Hepatitis C Cohort Study Group
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106424 (2014)
BACKGROUND:The CCR5 receptor, expressed on Th1 cells, may influence clinical outcomes of HCV infection. We explored a possible link between a CCR5 32-base deletion (CCR5delta32), resulting in the expression of a non-functioning receptor, and clinical
Externí odkaz:
https://doaj.org/article/eae7ad7ec51d41b483460d277f819dc6