Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Stephanie Niklaus"'
Autor:
Stephanie Niklaus, Stella M. K. Glasauer, Peter Kovermann, Kulsum F. Farshori, Lucia Cadetti, Simon Früh, Nicolas N. Rieser, Matthias Gesemann, Jingjing Zang, Christoph Fahlke, Stephan C. F. Neuhauss
Publikováno v:
Open Biology, Vol 14, Iss 7 (2024)
In the central nervous system of vertebrates, glutamate serves as the primary excitatory neurotransmitter. However, in the retina, glutamate released from photoreceptors causes hyperpolarization in post-synaptic ON-bipolar cells through a glutamate-g
Externí odkaz:
https://doaj.org/article/865a9d9b0c7d4231b313d2574304693f
Autor:
Karin Tuschl, Richard J. White, Chintan Trivedi, Leonardo E. Valdivia, Stephanie Niklaus, Isaac H. Bianco, Chris Dadswell, Ramón González-Méndez, Ian M. Sealy, Stephan C. F. Neuhauss, Corinne Houart, Jason Rihel, Stephen W. Wilson, Elisabeth M. Busch-Nentwich
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 6 (2022)
Manganese neurotoxicity is a hallmark of hypermanganesemia with dystonia 2, an inherited manganese transporter defect caused by mutations in SLC39A14. To identify novel potential targets of manganese neurotoxicity, we performed transcriptome analysis
Externí odkaz:
https://doaj.org/article/f65f7e53350a476f8c1a355ab69555a3
Autor:
Peter M. Maloca, Philipp L. Müller, Aaron Y. Lee, Adnan Tufail, Konstantinos Balaskas, Stephanie Niklaus, Pascal Kaiser, Susanne Suter, Javier Zarranz-Ventura, Catherine Egan, Hendrik P. N. Scholl, Tobias K. Schnitzer, Thomas Singer, Pascal W. Hasler, Nora Denk
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Maloca et al. implement convolutional neural network (CNN) to automatically segment OCT images obtained from cynomolgus monkeys. The results are compared to annotations generated by human graders. The ambiguity in ground truth had noteworthy impact o
Externí odkaz:
https://doaj.org/article/05979fb5418e464a9cf6a4f9447c2d75
Autor:
Stephanie Niklaus, Pascal W Hasler, Timothy Bryant, Sébastien Desgent, Mark Vezina, Tobias K Schnitzer, Peter M Maloca, Nora Denk
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237858 (2020)
The main objective of the study was to analyze deviations in retinal nerve fiber layer (RNFL) thickness measurements caused by the displacement of circular optic disc optical coherence tomography scans. High-density radial scans of the optic nerve he
Externí odkaz:
https://doaj.org/article/0cce6dc3be5b465eb578bae94dd50464
Publikováno v:
Animals, Vol 10, Iss 3, p 422 (2020)
Due to the lack of L-cones in the rodent retina, it is generally assumed that red light is invisible to rodents. Thus, red lights and red filter foils are widely used in rodent husbandry and experimentation allowing researchers to observe animals in
Externí odkaz:
https://doaj.org/article/5ec4fcd1bf1a4b77a46c659856c3f0f7
Autor:
Stephanie Niklaus, Stella M.K. Glasauer, Peter Kovermann, Kulsum F. Farshori, Lucia Cadetti, Simon Früh, Nicolas N. Rieser, Matthias Gesemann, Christoph Fahlke, Stephan C.F. Neuhauss
In the central nervous system of vertebrates, glutamate serves as the primary excitatory neurotransmitter. However, in the retina, glutamate released from photoreceptors causes hyperpolarization in postsynaptic ON-bipolar cells through a glutamate-ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::010987db56cdca0522516e138a7c115c
https://doi.org/10.1101/2023.05.01.538911
https://doi.org/10.1101/2023.05.01.538911
Autor:
Ecem Aydin, Stephan C.F. Neuhauss, Ahmed Jamali, Adriana L. Hotz, Nathalie Jurisch-Yaksi, Laetitia Lalla, Nicolas N. Rieser, Sverre Myren-Svelstad, Emre Yaksi, Stephanie Niklaus
Publikováno v:
Glia, 70 (1)
Glia
Glia
Astroglial excitatory amino acid transporter 2 (EAAT2, GLT-1, and SLC1A2) regulates the duration and extent of neuronal excitation by removing glutamate from the synaptic cleft. Hence, an impairment in EAAT2 function could lead to an imbalanced brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4936e621e265ff168a781bd02db68048
https://www.zora.uzh.ch/id/eprint/210148/
https://www.zora.uzh.ch/id/eprint/210148/
Autor:
Adriana L. Hotz, Ahmed Jamali, Nicolas N. Rieser, Stephanie Niklaus, Ecem Aydin, Sverre Myren‐Svelstad, Laetitia Lalla, Nathalie Jurisch‐Yaksi, Emre Yaksi, Stephan C. F. Neuhauss
Publikováno v:
Glia. 70
Autor:
Ecem Aydin, Sverre Myren-Svelstad, Emre Yaksi, Stephanie Niklaus, Adriana L. Hotz, Stephan C.F. Neuhauss, Ahmed Jamali, Nathalie Jurisch-Yaksi, Laetitia Lalla, Nicolas N. Rieser
Astroglial excitatory amino acid transporter 2 (EAAT2, GLT-1, SLC1A2) regulates the duration and extent of neuronal excitation by removing glutamate from the synaptic cleft. Hence, an impairment in EAAT2 function could lead to an imbalanced neural ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b811614e6e0a53addb382938d09b1e79
https://doi.org/10.1101/2021.03.16.435577
https://doi.org/10.1101/2021.03.16.435577
Autor:
Karin Tuschl, Richard J. White, Chintan Trivedi, Leonardo E. Valdivia, Stephanie Niklaus, Isaac H. Bianco, Chris Dadswell, Ramón González-Méndez, Ian M. Sealy, Stephan C. F. Neuhauss, Corinne Houart, Jason Rihel, Stephen W. Wilson, Elisabeth M. Busch-Nentwich
Publikováno v:
Disease modelsmechanisms. 15(6)
Manganese neurotoxicity is a hallmark of hypermanganesemia with dystonia 2, an inherited manganese transporter defect caused by mutations in SLC39A14. To identify novel potential targets of manganese neurotoxicity, we performed transcriptome analysis