Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stephanie Nemec"'
Autor:
Panthipa Suwannakot, Stephanie Nemec, Newton Gil Peres, Eric Y. Du, Kristopher A. Kilian, Katharina Gaus, Maria Kavallaris, J. Justin Gooding
Publikováno v:
ACS Biomaterials Science & Engineering. 9:1362-1376
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ccb729f921d511e3c89bdf6ddca3730
https://doi.org/10.1021/acsbiomaterials.2c01252
https://doi.org/10.1021/acsbiomaterials.2c01252
Autor:
Pallavi Srivastava, Sara Romanazzo, Chantal Kopecky, Stephanie Nemec, Jake Ireland, Thomas G. Molley, Kang Lin, Pavithra B. Jayathilaka, Elvis Pandzic, Avani Yeola, Vashe Chandrakanthan, John Pimanda, Kristopher Kilian
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
Gastrulation is a stage in embryo development where three germ layers arise to dictate the human body plan. In vitro models of gastrulation have been demonstrated by treating pluripotent stem cells with soluble morphogens to trigger differentiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c808ff093c11d40c87b74d22fd9a3dc6
https://pubmed.ncbi.nlm.nih.gov/36519269
https://pubmed.ncbi.nlm.nih.gov/36519269
Publikováno v:
Journal of Visualized Experiments.
Structurally, bone tissue is an inorganic-organic composite containing metabolically active cells embedded within a hierarchical, highly mineralized matrix. This organization is challenging to replicate due to the heterogeneous environment of bone. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3815be666f6fe0f2568f5a008d3f4484
https://doi.org/10.3791/63943-v
https://doi.org/10.3791/63943-v
Autor:
Stephanie Nemec, Sylvia Ganda, Karrar Al Taief, Chantal Kopecky, Rhiannon Kuchel, Hélène Lebhar, Christopher P. Marquis, Pall Thordarson, Kristopher A. Kilian
Publikováno v:
ACS applied bio materials.
Laboratory models of the tumor microenvironment require control of mechanical and biochemical properties to ensure accurate mimicry of patient disease. In contrast to pure natural or synthetic materials, hybrid approaches that pair recombinant protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e7defd4fb81716c23c2a1c697d3d73
https://pubmed.ncbi.nlm.nih.gov/35670558
https://pubmed.ncbi.nlm.nih.gov/35670558
Autor:
Kristopher A. Kilian, Gagan K. Jalandhra, Aleczandria S. Tiffany, Brendan A.C. Harley, Stephanie Nemec, Thomas G. Molley, Amrutha Patkunarajah, Kate Poole, Tzong-Tyng Hung
Publikováno v:
Biomater Sci
The tissue microenvironment contains a complex assortment of multiple cell types, matrices, and vessel structures, which is difficult to reconstruct in vitro. Here, we demonstrate model tumor microenvironments formed through direct writing of vascula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74777baca2d226e95f7ce4b1ee8f2e11
https://doi.org/10.1039/d1bm00574j
https://doi.org/10.1039/d1bm00574j
Autor:
Kristopher A. Kilian, Stephanie Nemec
Publikováno v:
Nature Reviews Materials. 6:69-83
The dynamic epigenetic landscape directs gene expression patterns that dictate cellular form and function, and drive the assembly of cells into tissues. The high degree of plasticity in the epigenetic landscape of mammalian cells is directed by mater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2f1da387d9b08ad88b5f305e9c0adfa
https://doi.org/10.1038/s41578-020-00238-z
https://doi.org/10.1038/s41578-020-00238-z
Autor:
Pavithra B. Jayathilaka, Elvis Pandzic, Jake Ireland, Sara Romanazzo, Avani Yeola, Thomas G. Molley, Kristopher A. Kilian, John E. Pimanda, Stephanie Nemec, Vashe Chandrakanthan, Pallavi Srivastava
Embryogenesis is orchestrated through local morphogen gradients and endometrial constraints that give rise to the three germ layers in a well-defined assembly. In vitro models of embryogenesis have been demonstrated by treating pluripotent stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8831ed7bef31f9e96cb7595e42d268bc
https://doi.org/10.1101/2021.10.28.466327
https://doi.org/10.1101/2021.10.28.466327
Publikováno v:
Advanced Healthcare Materials. :2201696
Nanoparticle drug formulations have many advantages for cancer therapy due to benefits in targeting selectivity, lack of systemic toxicity, and increased drug concentration in the tumor microenvironment after delivery. However, the promise of nanomed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4de0705c3eda8ee65bc27047fb1422
https://doi.org/10.1002/adhm.202201696
https://doi.org/10.1002/adhm.202201696
Autor:
George Sharbeen, Kristopher A. Kilian, Janet Youkhana, Paul Timpson, Qing Li, Joey Lam, Celine Heu, Jingxiao Zhong, Stephanie Nemec, Phoebe A. Phillips
Publikováno v:
Advanced biology. 5(6)
Interfacial cues in the tumor microenvironment direct the activity and assembly of multiple cell types. Pancreatic cancer, along with breast and prostate cancers, is enriched with cancer-associated fibroblasts (CAFs) that activate to coordinate the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8fd11e007dbea30be3b68603e53f8b
https://pubmed.ncbi.nlm.nih.gov/33754491
https://pubmed.ncbi.nlm.nih.gov/33754491
Autor:
Aleczandria S. Tiffany, Brendan A.C. Harley, Kristopher A. Kilian, Gagan K. Jalandhra, Tzong-Tyng Hung, Thomas G. Molley, Stephanie Nemec
The tissue microenvironment is comprised of a complex assortment of multiple cell types, matrices, membranes and vessel structures. Emulating this complex and often hierarchical organization in vitro has proved a considerable challenge, typically inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f10f2b2827a69357eb4bd0d7219269
https://doi.org/10.1101/2020.08.30.274654
https://doi.org/10.1101/2020.08.30.274654