Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stephanie Needham"'
Autor:
Lucy I. Crouch, Marcelo V. Liberato, Paulina A. Urbanowicz, Arnaud Baslé, Christopher A. Lamb, Christopher J. Stewart, Katie Cooke, Mary Doona, Stephanie Needham, Richard R. Brady, Janet E. Berrington, Katarina Madunic, Manfred Wuhrer, Peter Chater, Jeffery P. Pearson, Robert Glowacki, Eric C. Martens, Fuming Zhang, Robert J. Linhardt, Daniel I. R. Spencer, David N. Bolam
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Epithelial cells that line the gut secrete complex glycoproteins that form a mucus layer to protect the gut wall from enteric pathogens. Here, the authors provide a comprehensive characterisation of endo-acting glycoside hydrolases expressed by mucin
Externí odkaz:
https://doaj.org/article/34729e0035e248979eeaf2cddb4c661b
Autor:
Emily K. Glover, R. Alexander Speight, Despina Televantou, Stephanie Needham, Neil S. Sheerin
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-5 (2020)
Abstract Background Post-transplant lymphoproliferative disease is a recognized complication following solid organ transplantation. This is usually a B cell disease and frequently associated with Epstein Barr virus infection, although T cell PTLD can
Externí odkaz:
https://doaj.org/article/525c1909838b4f2fa0b0373ce737cd4b
Autor:
David J. Swan, Dominik Aschenbrenner, Christopher A. Lamb, Krishnendu Chakraborty, Jonathan Clark, Sumeet Pandey, Karin R. Engelhardt, Rui Chen, Athena Cavounidis, Yuchun Ding, Natalio Krasnogor, Christopher D. Carey, Meghan Acres, Stephanie Needham, Andrew J. Cant, Peter D. Arkwright, Anita Chandra, Klaus Okkenhaug, Holm H. Uhlig, Sophie Hambleton
Publikováno v:
Haematologica, Vol 104, Iss 10 (2019)
Externí odkaz:
https://doaj.org/article/4f6e2df160434dd095e8d7ffcfc30910
Autor:
Lisa Redford, Ghanim Alhilal, Stephanie Needham, Ottie O'Brien, Julie Coaker, John Tyson, Leonardo Maldaner Amorim, Iona Middleton, Osagi Izuogu, Mark Arends, Anca Oniscu, Ángel Miguel Alonso, Sira Moreno Laguna, Richard Gallon, Harsh Sheth, Mauro Santibanez-Koref, Michael S Jackson, John Burn
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0203052 (2018)
Somatic mutations in mononucleotide repeats are commonly used to assess the mismatch repair status of tumours. Current tests focus on repeats with a length above 15bp, which tend to be somatically more unstable than shorter ones. These longer repeats
Externí odkaz:
https://doaj.org/article/3e880ba13c9140f9962856f4f8dc8fd2
Autor:
Simon P Bach, Alexandra Gilbert, Kristian Brock, Stephan Korsgen, Ian Geh, James Hill, Talvinder Gill, Paul Hainsworth, Matthew G Tutton, Jim Khan, Jonathan Robinson, Mark Steward, Christopher Cunningham, Bruce Levy, Alan Beveridge, Kelly Handley, Manjinder Kaur, Natalie Marchevsky, Laura Magill, Ann Russell, Philip Quirke, Nicholas P West, David Sebag-Montefiore, Gina Brown, Peter Antonio, Alex Vince, Nick Hilken, Chakanaka Sidile, Adrian Wilcockson, Richard Peto, Tom Crosby, Brendan Moran, Julie Olliff, Katti Ashok, Simone Slawik, Andrew Smethurst, Rajaram Sripadam, Veena Tagore, Monica Terlizzo, Bearn Philip, Robert Davies, Susan Dodd, Sharadah Essapen, Pasha Nisar, Alexandra Stewart, Jonathan Trickett, Bansal Ashish, Peter Billings, Palanichamy Chandran, Conor Corr, Edward Favill, Simon Gollins, Peter Marsh, Andrew Maw, Rakha Neupane, Ramesh Rajagopal, Rachel Cooper, John Griffith, Paul Hatfield, Andy Lowe, Julian Ostrowski, Rhian Simpson, Richard Adams, Robert Bleehen, Michael Davies, Meleri Morgan, Darren Boone, Nicola Lacey, Ian Seddon, Bruce Sizer, Helen Stunell, Shaobin Wu, Maher Hadaki, Dominic Blunt, Susan Cleator, Ara Darzi, Robert Goldin, Paul Ziprin, Mike Dobson, Mark Pitt, Shabbir Susnerwala, Deborah Williamson, Georgina Howarth, Stephen Lee, Paul Wright, Tim Hoare, Alan Horgan, Fiona McDonald, Stephanie Needham, John Scott, Timothy Simmons, Debashis Biswas, James Hernon, Gaurav Kapur, Sandeep Kapur, James Sington, Christopher Speakman, William Stebbings, Stuart Williams, Madhavi Adusumalli, Anil Agarwal, David Borowski, Dharmendra Garg, Mohammed Hegab, Catherine Hobday, Veena Rao, Jyotsna Shrimankar, Mohamed Tabaqchali, David Wilson, Oliver Jones, Neil Mortensen, Andrew Slater, Aron Szuts, Lai Wang, Bryan Warren, Andrew Weaver, Mukhtar Ahmad, Julian Alexander, Maxine Flubacher, David Tarver, Suhail Baluch, Richard Beable, David Cowlishaw, Antony Higginson, Prokopios Vogiatzis, Neil Cruickshank, Howard Joy, David Peake, Ulises Zanetto, Mark Saunders, Arthur Sun-Myint, Mark Teo, Arthur Allan, John Glaholm, Mark Goldstein, Rahul Hejmadi, Gerald Langman, Dion Morton, Cyril Nelson, Deborah Tattersall, Stephen Falk, Robert Longman, Huw Roach, Jamshed Shabbir, Golda Shelley-Fraser, Michael Thomas, Neil Cripps, Yasser Haba, Guy Harris, Max Hookway, Jay Simson, Angela Skull, Tijani Umar
Publikováno v:
The Lancet. Gastroenterology & Hepatology
Summary Background Radical surgery via total mesorectal excision might not be the optimal first-line treatment for early-stage rectal cancer. An organ-preserving strategy with selective total mesorectal excision could reduce the adverse effects of tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0429cb08c4dbffa6cf68653420de5021
https://eprints.whiterose.ac.uk/170564/1/PIIS2468125320303332.pdf
https://eprints.whiterose.ac.uk/170564/1/PIIS2468125320303332.pdf
Autor:
Katarina Madunić, Mary Doona, Stephanie Needham, Manfred Wuhrer, Robert J. Linhardt, Robert W. P. Glowacki, David N. Bolam, Daniel Spencer, Christopher A. Lamb, Paulina A. Urbanowicz, Marcelo Vizoná Liberato, Christopher J. Stewart, Eric C. Martens, Fuming Zhang, J. P. Pearson, Peter I. Chater, Katie Cooke, Janet E. Berrington, Arnaud Baslé, Lucy I. Crouch, Richard R. W. Brady
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Nature Communications
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Nature Communications
The thick mucus layer of the gut provides a barrier to infiltration of the underlying epithelia by both the normal microbiota and enteric pathogens. Some members of the microbiota utilise mucin glycoproteins as a nutrient source, but a detailed under
Autor:
Stephanie Needham, Neil S. Sheerin, Emily K. Glover, R. Alexander Speight, Despina Televantou
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-5 (2020)
BMC Nephrology
BMC Nephrology
Background Post-transplant lymphoproliferative disease is a recognized complication following solid organ transplantation. This is usually a B cell disease and frequently associated with Epstein Barr virus infection, although T cell PTLD can occur. T
Autor:
Jonathan Clark, Christopher D. Carey, Athena Cavounidis, Meghan Acres, Klaus Okkenhaug, Yuchun Ding, Sophie Hambleton, Anita Chandra, Peter D. Arkwright, Stephanie Needham, Rui Chen, Holm H. Uhlig, Natalio Krasnogor, Sumeet Pandey, Krishnendu Chakraborty, Dominik Aschenbrenner, David J. Swan, Andrew J. Cant, Karin R. Engelhardt, Christopher A. Lamb
Phosphoinositide 3-kinase δ (PI3Kδ), a lipid kinase consisting of a catalytic (p110δ, encoded by PIK3CD) and a regulatory subunit (p85, encoded by PIK3R1), generates the second messenger phosphatidylinositol (3,4,5)-trisphosphate (PIP3) in the pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373d071c8a04c295d863147584cfd616
https://www.repository.cam.ac.uk/handle/1810/292933
https://www.repository.cam.ac.uk/handle/1810/292933
Autor:
Sharon A Melmore, Nikita Agrawal, Jessica K Dyson, David Jones, Tim Hoare, Stephanie Needham, Nick P Thompson
Publikováno v:
World Journal of Gastroenterology
We report a case of ileo-colonic Histoplasmosis without apparent respiratory involvement in a patient who had previously undergone an orthotopic liver transplant (OLT) for primary biliary cholangitis 15 years earlier. The recipient lived in the Unite