Výsledky vyhledávání - "Stephanie N. Weiss"

Akademický článek

In Vivo Photoacoustic Ultrasound (PAUS) Assay for Monitoring Tendon Collagen Compositional Changes during Injury and Healing

Autor: Joseph B. Newton, Courtney A. Nuss, Stephanie N. Weiss, Rebecca L. Betts, Chandra M. Sehgal, Louis J. Soslowsky

Publikováno v: Diagnostics, Vol 14, Iss 14, p 1498 (2024)

Tendon injury and healing involve significant changes to tissue biology and composition. Current techniques often require animal sacrifice or tissue destruction, limiting assessment of dynamic changes in tendons, including treatment response, disease

Externí odkaz: https://doaj.org/article/6021c8e13e6149cda34d33673f962499

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Akademický článek

Decorin knockdown is beneficial for aged tendons in the presence of biglycan expression

Autor: Zakary M. Beach, Mihir S. Dekhne, Ashley B. Rodriguez, Stephanie N. Weiss, Thomas H. Adams, Sheila M. Adams, Mei Sun, David E. Birk, Louis J. Soslowsky

Publikováno v: Matrix Biology Plus, Vol 15, Iss , Pp 100114- (2022)

Decorin and biglycan are two major small leucine-rich proteoglycans (SLRPs) present in the tendon extracellular matrix that facilitate collagen fibrillogenesis, tissue turnover, and cell signal transduction. Previously, we demonstrated that knockout

Externí odkaz: https://doaj.org/article/78329dac72374b3ebe73282ada16ec88

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Akademický článek

Coordinate roles for collagen VI and biglycan in regulating tendon collagen fibril structure and function

Autor: Ryan J. Leiphart, Hai Pham, Tyler Harvey, Taishi Komori, Tina M. Kilts, Snehal S. Shetye, Stephanie N. Weiss, Sheila M. Adams, David E. Birk, Louis J. Soslowsky, Marian F. Young

Publikováno v: Matrix Biology Plus, Vol 13, Iss , Pp 100099- (2022)

Tendon is a vital musculoskeletal tissue that is prone to degeneration. Proper tendon maintenance requires complex interactions between extracellular matrix components that remain poorly understood. Collagen VI and biglycan are two matrix molecules t

Externí odkaz: https://doaj.org/article/8ff4cec26ecb461e91a26fcea0bdab01

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Post-injury tendon mechanics are not affected by tamoxifen treatment

Autor: Zakary M, Beach, Ashley K, Fung, Stephanie N, Weiss, Louis J, Soslowsky

Publikováno v: Connective Tissue Research. 64:75-81

A growing interest in the mechanisms that govern tendon healing has resulted in the develop-ment of tools, such as the tamoxifen-inducible mouse knockdown model, to address these questions. However, tamoxifen is a selective estrogen receptor modulato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac3bbfceb6a0822fbc9758b9104a196
https://doi.org/10.1080/03008207.2022.2097907

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Biglycan has a major role in maintenance of mature tendon mechanics

Autor: Zakary M. Beach, Kelsey A. Bonilla, Mihir S. Dekhne, Mei Sun, Thomas H. Adams, Sheila M. Adams, Stephanie N. Weiss, Ashley B. Rodriguez, Snehal S. Shetye, David E. Birk, Louis J. Soslowsky

Publikováno v: Journal of Orthopaedic Research. 40:2546-2556

Decorin and biglycan are two small leucine-rich proteoglycans (SLRPs) that regulate collagen fibrillogenesis and extracellular matrix assembly in tendon. The objective of this study was to determine the individual roles of these molecules in maintain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4f7c47cbc7d6cdea3b5143372d4bfb
https://doi.org/10.1002/jor.25299

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Pulsed electromagnetic field therapy alters early healing in a rat model of rotator cuff injury and repair: Potential mechanisms

Autor: Stephanie N. Weiss, Harina A. Raja, James T. Ryaby, Erik I. Waldorff, Julianne Huegel, Andrew F. Kuntz, Nianli Zhang, Courtney A. Nuss, Peter Y. W. Chan, Louis J. Soslowsky

Publikováno v: J Orthop Res

Rotator cuff repair failure remains common due to poor tendon healing, particularly at the enthesis. We previously showed that pulsed electromagnetic field (PEMF) therapy improved the mechanical properties of the rat supraspinatus tendon postoperativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9959085e248a50f1fc9d2e5649e05ae9
https://doi.org/10.1002/jor.25185

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Increasing Vascular Response to Injury Improves Tendon Early Healing Outcome in Aged Rats

Autor: Corinne N. Riggin, Stephanie N. Weiss, Ashley B. Rodriguez, Harina Raja, Mengcun Chen, Susan M. Schultz, Chandra M. Sehgal, Louis J. Soslowsky

Publikováno v: Ann Biomed Eng

Tendon injuries positively correlate with patient age, as aging has significant effects on tendon homeostatic maintenance and healing potential after injury. Vascularity is also influenced by age, with both clinical and animal studies demonstrating r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e55caeb2420fdedfcc93bc66abc5d8
https://pubmed.ncbi.nlm.nih.gov/35303172

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